用于无线视网膜假体的激光驱动微型金刚石植入物
Laser driven miniature diamond implant for wireless retinal prostheses
AI总结：
该研究设计并验证近红外激光供能的无线微型视网膜上刺激器，通过ASIC、高效PV电池、光电遥测与金刚石封装连接256个电极，实现高集成、低创伤和灵活刺激。
摘要：
本文报道了一种无线微型视网膜上刺激器植入物的设计与台式运行情况。该植入物采用近红外波长的安全照明进行光学供能和控制。使用搭载数字控制单元的专用集成电路（ASIC）来控制植入物的电极。该ASIC由先进光伏（PV）电池供电，并通过单个光电二极管进行编程。研究采用金刚石封装技术，在4.6 mm×3.7 mm×0.9 mm的植入物封装内实现了植入物光电电路的高密度集成，以及刺激芯片与256个电极之间的独立连接。植入物由单色功率转换效率达55%的超高效PV电池供电。板载光电检测电路具有3.7 MHz带宽，用于刺激参数的前向数据遥测。与采用感应耦合线圈的植入物相比，激光功率传输可实现高度小型化并降低手术复杂性。所提出的器件结合了植入物小型化的优势以及专用刺激芯片所提供的灵活刺激策略。这一进展为实现具备复杂功能的全无线、小型化、微创植入物提供了途径。
英文摘要：
The design and benchtop operation of a wireless miniature epiretinal stimulator implant is reported. The implant is optically powered and controlled using safe illumination at near-infrared wavelengths. An application-specific integrated circuit (ASIC) hosting a digital control unit is used to control the implant's electrodes. The ASIC is powered using an advanced photovoltaic (PV) cell and programmed using a single photodiode. Diamond packaging technology is utilized to achieve high-density integration of the implant optoelectronic circuitry, as well as individual connections between a stimulator chip and 256 electrodes, within a 4.6 mm x 3.7 mm x 0.9 mm implant package. An ultrahigh efficiency PV cell with a monochromatic power conversion efficiency of 55% is used to power the implant. On-board photodetection circuity with a bandwidth of 3.7 MHz is used for forward data telemetry of stimulation parameters. In comparison to implants which utilize inductively coupled coils, laser power delivery enables a high degree of miniaturization and lower surgical complexity. The device presented combines the benefits of implant miniaturization and a flexible stimulation strategy provided by a dedicated stimulator chip. This development provides a route to fully wireless miniaturized minimally invasive implants with sophisticated functionalities.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
