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arXiv 2406.13645eess.IVcs.CV

利用无源主动域适应与新型多中心数据集推进UWF-SLO血管分割

Advancing UWF-SLO Vessel Segmentation with Source-Free Active Domain Adaptation and a Novel Multi-Center Dataset

Hong Kong University of Science and Technology (Guangzhou)(香港科技大学(广州));University of Electronic Science and Technology of China(电子科技大学);West China Hospital, Sichuan University(四川大学华西医院);Chengdu First People’s Hospital(成都市第一人民医院);Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences(中国科学院深圳先进技术研究院);The Hong Kong University of Science and Technology(香港科技大学)

Hongqiu Wang, Xiangde Luo, Wu Chen, Qingqing Tang, Mei Xin, Qiong Wang, Lei Zhu

AI总结:

针对UWF-SLO血管分割的域偏移与标注难题,提出基于CUP策略的无源主动域适应框架,构建首个多中心MU-VS数据集,实验证明该方法以极少标注超越现有方法,具备临床实用价值。

摘要:

超宽视野扫描激光检眼镜(Ultra-Wide-Field Scanning Laser Ophthalmoscopy, UWF-SLO)图像的精准血管分割对视网膜疾病诊断至关重要。尽管近期技术在血管分割中已展现出令人鼓舞的效果,但受域偏移影响,在某一医学数据集上训练的模型在其他数据集上往往表现不佳。同时,手动标注高分辨率UWF-SLO图像是一项极具挑战性、耗时且成本高昂的工作。针对上述问题,本研究提出了首个基于图像块的主动域适应框架。通过设计的级联不确定性-优势度(Cascade Uncertainty-Predominance, CUP)选择策略主动推荐少量有价值的图像块用于标注和模型微调,我们的方法显著提升了不同医学中心间UWF-SLO血管分割的准确率。此外,我们标注并构建了首个多中心UWF-SLO血管分割(Multi-center UWF-SLO Vessel Segmentation, MU-VS)数据集以推动该领域研究,该数据集涵盖多家机构的数据,可作为跨中心评估的宝贵资源,用于验证我们方法的有效性和鲁棒性。实验结果表明,我们的方法优于现有的域适应和主动学习方法,以最少的标注量大幅缩小了上限与下限之间的性能差距,凸显了该方法的临床实用价值。我们将发布数据集和代码以推动相关研究:https://github.com/whq-xxh/SFADA-UWF-SLO。

英文摘要:

Accurate vessel segmentation in Ultra-Wide-Field Scanning Laser Ophthalmoscopy (UWF-SLO) images is crucial for diagnosing retinal diseases. Although recent techniques have shown encouraging outcomes in vessel segmentation, models trained on one medical dataset often underperform on others due to domain shifts. Meanwhile, manually labeling high-resolution UWF-SLO images is an extremely challenging, time-consuming and expensive task. In response, this study introduces a pioneering framework that leverages a patch-based active domain adaptation approach. By actively recommending a few valuable image patches by the devised Cascade Uncertainty-Predominance (CUP) selection strategy for labeling and model-finetuning, our method significantly improves the accuracy of UWF-SLO vessel segmentation across diverse medical centers. In addition, we annotate and construct the first Multi-center UWF-SLO Vessel Segmentation (MU-VS) dataset to promote this topic research, comprising data from multiple institutions. This dataset serves as a valuable resource for cross-center evaluation, verifying the effectiveness and robustness of our approach. Experimental results demonstrate that our approach surpasses existing domain adaptation and active learning methods, considerably reducing the gap between the Upper and Lower bounds with minimal annotations, highlighting our method's practical clinical value. We will release our dataset and code to facilitate relevant research: https://github.com/whq-xxh/SFADA-UWF-SLO.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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