使用受试者调整的肌肉骨骼模型验证踝足矫形器对脊髓损伤步态估计效果
Validation of the estimated Effect of Ankle Foot Orthoses on Spinal Cord Injury Gait Using Subject-Adjusted Musculoskeletal Models
AI总结：
本文提出一种受试者调整的肌肉骨骼建模方法，用于在制造前预测踝足矫形器对脊髓损伤患者步态的生物力学影响，并通过仿真验证了其在运动学预测和对称性改善评估中的有效性。
摘要：
通过肌肉骨骼模型对病理性步态中的辅助装置进行仿真，具有在制造前估计该装置在多个生物力学变量中的效果以及装置特性的潜力和优势。在本研究中，我们引入了一种新颖的肌肉骨骼建模方法，用于模拟踝足矫形器（AFO）对脊髓损伤（SCI）个体步态的生物力学影响。利用瑞士截瘫中心的数据，我们为SCI-AFO使用者构建了解剖学和肌肉学上缩放的模型，旨在预测步态运动学和动力学变化。这项工作的重要性在于其有潜力通过实现辅助装置的制造前评估来增强康复策略并改善生活质量。尽管肌肉骨骼模型已在其他疾病中应用于模拟助行器效果，但目前尚无针对SCI步态的预测模型。通过RMSE进行的评估显示，与其他病理情况相比结果相似，运动学中的仿真误差范围在0.23至2.3度之间。此外，该模型能够捕捉踝关节肌肉不对称性，并预测使用AFO后的对称性改善。然而，仿真并未揭示所有AFO效果，表明需要更个性化的模型参数和优化的肌肉激活，以完全复现矫形器对SCI步态的影响。
英文摘要：
Simulation of assistive devices on pathological gait through musculoskeletal models offers the potential and advantages of estimating the effect of the device in several biomechanical variables and the device characteristics ahead of manufacturing. In this study, we introduce a novel musculoskeletal modelling approach to simulate the biomechanical impact of ankle foot orthoses (AFO) on gait in individuals with spinal cord injury (SCI). Leveraging data from the Swiss Paraplegic Center, we constructed anatomically and muscularly scaled models for SCI-AFO users, aiming to predict changes in gait kinematics and kinetics. The importance of this work lies in its potential to enhance rehabilitation strategies and improve quality of life by enabling the pre-manufacturing assessment of assistive devices. Despite the application of musculoskeletal models in simulating walking aids effects in other conditions, no predictive model currently exists for SCI gait. Evaluation through RMSE showed similar results compared with other pathologies, simulation errors ranged between 0.23 to 2.3 degrees in kinematics. Moreover, the model was able to capture ankle joint muscular asymmetries and predict symmetry improvements with AFO use. However, the simulation did not reveal all the AFO effects, indicating a need for more personalized model parameters and optimized muscle activation to fully replicate orthosis effects on SCI gait.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
