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arXiv 2403.12908stat.ME
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高维点过程的正则化谱估计

Regularised Spectral Estimation for High-Dimensional Point Processes

Carla Pinkney, Carolina Euan, Alex Gibberd, Ali Shojaie

AI总结:

针对高维脉冲列数据谱估计的困难,提出适用于点过程的正则化谱估计新方法,建立渐近性质并在合成与真实神经数据上验证其推断大脑连接性的有效性。

摘要:

现代技术的进步使得同时记录神经脉冲活动成为可能,这在统计上可以由多元点过程来表示。我们通过谱密度矩阵来刻画该过程的二阶结构,它是协方差矩阵在频域中的等价物。在神经元分析的背景下,基于谱密度矩阵的统计量可用于推断大脑网络中单个神经元之间的连接性。然而,脉冲列数据的高维特性意味着计算这些统计量通常很困难,有时甚至是不可能的。在本研究中,我们讨论了基于正则化的谱估计方法的重要性,并提出适用于点过程场景的新颖方法。我们为所提出的估计量建立了渐近性质,并在由多元Hawkes过程模拟的合成数据上评估了它们的性能。最后,我们将该方法应用于神经科学脉冲列数据,以说明其推断大脑连接性的能力。

英文摘要:

Advances in modern technology have enabled the simultaneous recording of neural spiking activity, which statistically can be represented by a multivariate point process. We characterise the second order structure of this process via the spectral density matrix, a frequency domain equivalent of the covariance matrix. In the context of neuronal analysis, statistics based on the spectral density matrix can be used to infer connectivity in the brain network between individual neurons. However, the high-dimensional nature of spike train data mean that it is often difficult, or at times impossible, to compute these statistics. In this work, we discuss the importance of regularisation-based methods for spectral estimation, and propose novel methodology for use in the point process setting. We establish asymptotic properties for our proposed estimators and evaluate their performance on synthetic data simulated from multivariate Hawkes processes. Finally, we apply our methodology to neuroscience spike train data in order to illustrate its ability to infer brain connectivity.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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