用于定量磁化率成像（QSM）和R2*成像的运动与时间B0漂移校正：基于双回波螺旋导航仪和共轭相位重建
Motion and temporal B0 shift corrections for quantitative susceptibility mapping (QSM) and R2* mapping using dual-echo spiral navigators and conjugate-phase reconstruction
AI总结：
本研究提出一种基于双回波三维螺旋导航仪和共轭相位重建的方法，联合校正运动和时间B0漂移，有效提升QSM和R2*成像质量。
摘要：
目的：开发一种高效的基于导航仪的运动和时间B0漂移校正技术，用于三维多回波梯度回波（ME-GRE）MRI，以实现定量磁化率成像（QSM）和R2*成像。理论与方法：设计了一种双回波三维螺旋导航仪，与笛卡尔ME-GRE采集交错进行，从而能够同时采集低和高回波时间信号。此外，我们设计了一种新颖的基于共轭相位的重建方法，用于联合校正运动和时间B0漂移。我们进行了数值模拟和人体在体扫描，以评估这些方法的性能。结果：数值模拟和人体脑部扫描表明，所提出的技术成功校正了由头部运动和时间B0变化引起的伪影。基于共轭相位的B0变化校正可在少于10个聚类k空间段上高效执行。在体扫描显示，将时间B0校正与运动校正相结合，进一步减少了伪影，并提高了R2*和QSM图像的质量。结论：我们提出的使用三维螺旋导航仪和新型共轭相位重建方法的方法，可以改善基于MR的磁化率相关测量。
英文摘要：
Purpose: To develop an efficient navigator-based motion and temporal B0 shift correction technique for 3D multi-echo gradient-echo (ME-GRE) MRI for quantitative susceptibility mapping (QSM) and R2* mapping. Theory and Methods: A dual-echo 3D spiral navigator was designed to interleave with the Cartesian ME-GRE acquisitions, allowing the acquisition of both low- and high-echo time signals. We additionally designed a novel conjugate-phase based reconstruction method for the joint correction of motion and temporal B0 shifts. We performed both numerical simulation and in vivo human scans to assess the performance of the methods. Results: Numerical simulation and human brain scans demonstrated that the proposed technique successfully corrected artifacts induced by both head motions and temporal B0 changes. Efficient B0-change correction with conjugate-phase reconstruction can be performed on less than 10 clustered k-space segments. In vivo scans showed that combining temporal B0 correction with motion correction further reduced artifacts and improved image quality in both R2* and QSM images. Conclusion: Our proposed approach of using 3D spiral navigators and a novel conjugate-phase reconstruction method can improve susceptibility-related measurements using MR.
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