arXivDaily arXiv每日学术速递 周一至周五更新
arXiv 2403.02544eess.IVcs.CVcs.LG
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使用深度学习在非对比剂钙化评分CT图像中进行冠状动脉分割

Coronary artery segmentation in non-contrast calcium scoring CT images using deep learning

Graylight Imaging(格雷莱特成像公司);University of Silesia(西里西亚大学);Silesian University of Technology(西里西亚工业大学);Silesian Center for Heart Diseases(西里西亚心脏病中心)

Mariusz Bujny, Katarzyna Jesionek, Jakub Nalepa, Karol Miszalski-Jamka, Katarzyna Widawka-Żak, Sabina Wolny, Marcin Kostur

AI总结:

针对非对比剂钙化评分CT中冠状动脉难以分割的问题,提出结合图像配准半自动生成GT的深度学习分割方法,并以人工网格到图像配准构建测试GT,使模型精度超过训练GT且接近评估者间一致性。

摘要:

在计算机断层扫描(CT)中精确定位冠状动脉,对于冠状动脉疾病的医学评估至关重要。尽管已有多种方法能够在心脏增强CT扫描中实现高质量的冠状动脉分割,但侵入性较低的非对比剂CT在这一领域的潜力仍未得到充分开发。由于此类精细解剖结构在这类医学图像中几乎不可见,现有方法通常具有高召回率和低精确率的特点,并且主要用于钙化评分背景下的动脉粥样硬化斑块筛选。本文针对这一研究空白,提出一种用于在多厂商、心电门控非对比剂心脏CT图像中分割冠状动脉的深度学习算法,该算法得益于一种通过图像配准半自动生成Ground Truth(GT,真值)的新颖框架。我们假设,在这种情况下,所提出的GT生成过程比人工分割高效得多,因为它能够快速生成大量多样化数据,从而获得具有良好泛化能力的模型。为了研究并全面评估基于这种方法的分割质量,我们提出一种新颖的人工网格到图像配准方法,并将其用于创建测试GT。实验研究表明,训练后的模型准确率显著高于训练所用GT,并且其Dice和clDice指标接近评估者间变异水平。

英文摘要:

Precise localization of coronary arteries in Computed Tomography (CT) scans is critical from the perspective of medical assessment of coronary artery disease. Although various methods exist that offer high-quality segmentation of coronary arteries in cardiac contrast-enhanced CT scans, the potential of less invasive, non-contrast CT in this area is still not fully exploited. Since such fine anatomical structures are hardly visible in this type of medical images, the existing methods are characterized by high recall and low precision, and are used mainly for filtering of atherosclerotic plaques in the context of calcium scoring. In this paper, we address this research gap and introduce a deep learning algorithm for segmenting coronary arteries in multi-vendor ECG-gated non-contrast cardiac CT images which benefits from a novel framework for semi-automatic generation of Ground Truth (GT) via image registration. We hypothesize that the proposed GT generation process is much more efficient in this case than manual segmentation, since it allows for a fast generation of large volumes of diverse data, which leads to well-generalizing models. To investigate and thoroughly evaluate the segmentation quality based on such an approach, we propose a novel method for manual mesh-to-image registration, which is used to create our test-GT. The experimental study shows that the trained model has significantly higher accuracy than the GT used for training, and leads to the Dice and clDice metrics close to the interrater variability.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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