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arXiv 2402.17643eess.SPeess.IV

用于超声定位显微成像的滤波延迟乘加波束形成的性能评估:初步结果

A Performance Evaluation of Filtered Delay Multiply and Sum Beamforming for Ultrasound Localization Microscopy: Preliminary Results

A. N. Madhavanunni, Niya Mariam Benoy, Mahesh Raveendranatha Panicker, Himanshu Shekhar

AI总结:

本文评估了滤波延迟乘加(F-DMAS)波束形成在超声定位显微成像中的性能,并与传统DAS方法比较,提出两种新图像质量度量,初步体外实验显示其对比度和横向分辨率均有提升。

摘要:

超快超声定位显微成像(ULM)在微血管成像中已展现出有前景的结果,克服了分辨率与穿透深度之间的典型权衡。将超声造影剂与高帧率成像相结合,使ULM能够可视化微血管并量化血流。然而,所获得的微血管图质量取决于接收信号的信噪比、图像重建技术以及所使用的微泡(MB)定位与跟踪算法。已报道的大多数ULM研究采用传统的延迟求和(DAS)波束形成技术进行图像重建,尽管其对比度和分辨率有限。在本工作中,采用非偏转平面波发射的滤波延迟乘加(F-DMAS)波束形成方法用于ULM,并针对超声定位显微成像定位与跟踪工具箱中可用的不同定位算法,将其性能与基于传统DAS的方法进行了比较。我们还引入了两种新颖的图像质量度量,能够克服需要合适目标进行评估的传统质量指标的局限性。我们还报告了F-DMAS在B模式和功率多普勒图下用于微血管成像的初步体外研究。结果令人鼓舞,对比度和横向分辨率均得到增强,表明有必要开展进一步的实验研究。

英文摘要:

Ultrafast ultrasound localization microscopy (ULM), which has shown promising results in microvascular imaging, overcomes the typical trade-off between resolution and penetration depth. Combining ultrasound contrast agents and high frame rate imaging enables ULM to visualize microvasculature and quantify flow. However, the quality of the microvascular maps obtained depends on the signal-to-noise ratio of the received signals, image reconstruction techniques, and the microbubble (MB) localization and tracking algorithms used. Most reported research in ULM employs the conventional delay and sum (DAS) beamforming technique for image reconstruction despite its limited contrast and resolution. In this work, a filtered delay multiply and sum (F-DMAS) beamforming approach with non-steered plane wave transmit was employed for ULM, and its performance was compared with the conventional DAS-based approach for the different localization algorithms available in the Localization and Tracking Toolbox for Ultrasound Localization Microscopy. We also introduce two novel image quality measures that can overcome the limitations of conventional quality metrics that require suitable targets for evaluation. We also report the preliminary in-vitro investigation of F-DMAS with B-mode and power Doppler maps for microvascular imaging. The results are promising with enhanced contrast and lateral resolution, and suggest that further experimental studies are warranted.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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