基于矢量调制器的磁粒子成像中直接馈通的有源补偿
Vector Modulator Based Active Compensation of Direct Feedthrough in Magnetic Particle Imaging
AI总结：
本研究将基于矢量调制器和查找表算法的有源补偿技术从MRI适配至MPI，有效减少直接馈通干扰，成功恢复基频并显著提升检测灵敏度，满足干细胞跟踪等应用需求。
摘要：
在磁粒子成像（MPI）中，同时激励和信号采集会导致直接馈通干扰。虽然这种干扰在一定程度上可以通过无源补偿来缓解，但其时变特性需要有源补偿方法，以达到干细胞跟踪等应用所需的灵敏度水平。我们最近提出了一种用于MRI的有源补偿技术，该技术使用矢量调制器和基于查找表的算法来减少模拟域中的直接馈通。在这里，我们将该技术应用于MPI，展示了基频的成功恢复和检测灵敏度的显著提高。
英文摘要：
In magnetic particle imaging (MPI), simultaneous excitation and signal acquisition leads to direct feedthrough interference. While this interference can be mitigated up to some extent with passive compensation, its time-varying nature necessitates active compensation methods to achieve the sensitivity levels needed for applications such as stem cell tracking. We have recently proposed an active compensation technique for MRI, which uses a vector modulator and a lookup-table-based algorithm for reducing the direct feedthrough in the analog domain. Here, we adapt this technique to MPI, demonstrating a successful recovery of the fundamental frequency and a significant increase in detection sensitivity.
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