从二十年血压数据中学习：7500万次患者就诊中特定于人口统计学的模式
Learning from Two Decades of Blood Pressure Data: Demography-Specific Patterns Across 75 Million Patient Encounters
AI总结：
本研究分析了Emory Healthcare二十年间的7560万条血压记录，揭示了收缩压和舒张压随性别、年龄和种族变化的特定模式及其显著相关性，为个性化医疗干预提供了依据。
摘要：
高血压是一个日益普遍的全球健康问题，凸显了对血压（BP）动态进行有效监测和分析的必要性。我们分析了一个庞大的血压数据集，包含来自美国佐治亚州Emory Healthcare在2000年至2022年间收集的2,054,462名独立患者的75,636,128条记录，代表了人口学上的多样化群体。我们检查并比较了收缩压（SBP）和舒张压（DBP）二元变化的全人群统计数据，涵盖性别、年龄和种族/族裔。分析表明，男性的血压水平高于女性，并表现出随年龄变化的独特血压特征。值得注意的是，平均SBP随年龄持续上升，而平均DBP在四十岁年龄组达到峰值。在所研究的族裔群体中，黑人的血压略高且标准差更大。我们还在人群层面发现了SBP与DBP之间存在显著相关性，这一现象此前未被研究过。这些结果强调了特定于人口统计学的血压分析对临床诊断的重要性，并为开发个性化、特定于人口统计学的医疗干预措施提供了有价值的见解。
英文摘要：
Hypertension is a global health concern with an increasing prevalence, underscoring the need for effective monitoring and analysis of blood pressure (BP) dynamics. We analyzed a substantial BP dataset comprising 75,636,128 records from 2,054,462 unique patients collected between 2000 and 2022 at Emory Healthcare in Georgia, USA, representing a demographically diverse population. We examined and compared population-wide statistics of bivariate changes in systolic BP (SBP) and diastolic BP (DBP) across sex, age, and race/ethnicity. The analysis revealed that males have higher BP levels than females and exhibit a distinct BP profile with age. Notably, average SBP consistently rises with age, whereas average DBP peaks in the forties age group. Among the ethnic groups studied, Blacks have marginally higher BPs and a greater standard deviation. We also discovered a significant correlation between SBP and DBP at the population level, a phenomenon not previously researched. These results emphasize the importance of demography-specific BP analysis for clinical diagnosis and provide valuable insights for developing personalized, demography-specific healthcare interventions.
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