arXivDaily arXiv每日学术速递 周一至周五更新
arXiv周末暂无论文更新,休息一下吧,周末愉快~~
arXiv 2401.10014cs.LGeess.SP

通过路径发展网络优化心房颤动患者的用药决策

Optimizing Medication Decisions for Patients with Atrial Fibrillation through Path Development Network

University College London(伦敦大学学院)

Tian Xie

AI总结:

本文提出融合STOME、CNN与路径发展层的模型,利用12导联心电图预测房颤患者抗凝治疗建议,并在NPV为1时显著提升特异度。

摘要:

心房颤动(AF)是一种常见的心律失常,其特征是心房快速且不规则地收缩。由于心房内血流减缓,尤其是在易于形成血栓的左心耳中,AF会显著升高卒中风险。这些血栓可能迁移至脑动脉,导致缺血性卒中。为评估AF患者是否应被开具抗凝药,医生通常使用CHA2DS2-VASc评分系统。然而,抗凝药的使用必须谨慎,因为其会影响凝血功能。本研究提出一种机器学习算法,利用12导联心电图数据预测是否应建议AF患者接受抗凝治疗。在该模型中,我们使用STOME增强时间序列数据,随后通过卷积神经网络(CNN)进行处理。通过引入路径发展层,该模型在NPV为1的条件下实现了30.6%的特异度。相比之下,未采用路径发展的LSTM算法在相同NPV条件下仅产生2.7%的特异度。

英文摘要:

Atrial fibrillation (AF) is a common cardiac arrhythmia characterized by rapid and irregular contractions of the atria. It significantly elevates the risk of strokes due to slowed blood flow in the atria, especially in the left atrial appendage, which is prone to blood clot formation. Such clots can migrate into cerebral arteries, leading to ischemic stroke. To assess whether AF patients should be prescribed anticoagulants, doctors often use the CHA2DS2-VASc scoring system. However, anticoagulant use must be approached with caution as it can impact clotting functions. This study introduces a machine learning algorithm that predicts whether patients with AF should be recommended anticoagulant therapy using 12-lead ECG data. In this model, we use STOME to enhance time-series data and then process it through a Convolutional Neural Network (CNN). By incorporating a path development layer, the model achieves a specificity of 30.6% under the condition of an NPV of 1. In contrast, LSTM algorithms without path development yield a specificity of only 2.7% under the same NPV condition.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

↑