arXivDaily arXiv每日学术速递 周一至周五更新
arXiv 2311.03217eess.IVcs.CVcs.LG
收藏

利用Transformer改进基于多模态和纵向数据的乳腺癌分类与风险评估

Leveraging Transformers to Improve Breast Cancer Classification and Risk Assessment with Multi-modal and Longitudinal Data

New York University(纽约大学);NYU Langone Health(纽约大学朗格尼医学中心);NYU Grossman School of Medicine(纽约大学格罗斯曼医学院);New York University Abu Dhabi(纽约大学阿布扎比分校)

Yiqiu Shen, Jungkyu Park, Frank Yeung, Eliana Goldberg, Laura Heacock, Farah Shamout, Krzysztof J. Geras

AI总结:

提出多模态Transformer(MMT),融合乳腺X线摄影和超声数据并利用纵向影像,在130万次检查上训练,实现癌症检测AUROC 0.943和5年风险预测AUROC 0.826,优于单模态基线。

摘要:

乳腺癌筛查主要通过乳腺X线摄影进行,对于乳腺组织致密的女性,通常辅以超声检查。然而,现有的深度学习模型独立分析每种模态,错失了跨成像模态和时间整合信息的机会。在本研究中,我们提出了多模态Transformer(MMT),这是一种协同利用乳腺X线摄影和超声的神经网络,用于识别当前患有癌症的患者,并评估目前未患癌症患者未来患癌的风险。MMT通过自注意力聚合多模态数据,并通过将当前检查与既往影像进行比较来追踪组织的时间变化。MMT在130万次检查上训练,在检测现有癌症方面达到了0.943的AUROC,超过了强大的单模态基线。在5年风险预测方面,MMT达到了0.826的AUROC,优于先前基于乳腺X线摄影的风险模型。我们的研究凸显了多模态和纵向影像在癌症诊断和风险分层中的价值。

英文摘要:

Breast cancer screening, primarily conducted through mammography, is often supplemented with ultrasound for women with dense breast tissue. However, existing deep learning models analyze each modality independently, missing opportunities to integrate information across imaging modalities and time. In this study, we present Multi-modal Transformer (MMT), a neural network that utilizes mammography and ultrasound synergistically, to identify patients who currently have cancer and estimate the risk of future cancer for patients who are currently cancer-free. MMT aggregates multi-modal data through self-attention and tracks temporal tissue changes by comparing current exams to prior imaging. Trained on 1.3 million exams, MMT achieves an AUROC of 0.943 in detecting existing cancers, surpassing strong uni-modal baselines. For 5-year risk prediction, MMT attains an AUROC of 0.826, outperforming prior mammography-based risk models. Our research highlights the value of multi-modal and longitudinal imaging in cancer diagnosis and risk stratification.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

↑