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arXiv 2310.03559eess.IVcs.CV

MedSyn:文本引导的解剖感知高保真3D CT图像合成

MedSyn: Text-guided Anatomy-aware Synthesis of High-Fidelity 3D CT Images

Boston University(波士顿大学);Stanford University(斯坦福大学);Carnegie Mellon University(卡内基梅隆大学);University of Pittsburgh Medical Center(匹兹堡大学医学中心);University of Pittsburgh(匹兹堡大学)

Yanwu Xu, Li Sun, Wei Peng, Shuyue Jia, Katelyn Morrison, Adam Perer, Afrooz Zandifar, Shyam Visweswaran, Motahhare Eslami, Kayhan Batmanghelich

AI总结:

本文提出MedSyn方法,通过改进UNet架构的分层方案和结合分割掩码,实现文本引导的高保真3D肺部CT图像合成,在保留解剖细节方面优于现有GAN和扩散模型。

摘要:

本文介绍了一种创新方法,用于生成由文本信息引导的高质量3D肺部CT图像。尽管基于扩散的生成模型在医学成像中日益普及,但当前最先进的方法仅限于低分辨率输出,且未充分利用放射学报告中的丰富信息。放射学报告可通过提供额外指导并实现对图像合成的细粒度控制来增强生成过程。然而,将文本引导生成扩展到高分辨率3D图像会带来显著的内存和保留解剖细节方面的挑战。为解决内存问题,我们引入了一种使用改进UNet架构的分层方案。我们首先合成以文本为条件的低分辨率图像,作为后续生成器生成完整体积数据的基础。为确保生成样本的解剖合理性,我们通过将血管、气道和肺叶分割掩码与CT图像结合生成,提供进一步指导。该模型展示了使用文本输入和分割任务生成合成图像的能力。比较评估结果表明,与基于GAN和扩散技术的最先进模型相比,我们的方法表现出更优越的性能,特别是在准确保留裂隙线、气道和血管结构等关键解剖特征方面。这一创新引入了新的可能性。本研究聚焦于两个主要目标:(1)开发一种基于文本提示和解剖组件创建图像的方法,以及(2)具备以解剖元素为条件生成新图像的能力。图像生成的进步可应用于增强众多下游任务。

英文摘要:

This paper introduces an innovative methodology for producing high-quality 3D lung CT images guided by textual information. While diffusion-based generative models are increasingly used in medical imaging, current state-of-the-art approaches are limited to low-resolution outputs and underutilize radiology reports' abundant information. The radiology reports can enhance the generation process by providing additional guidance and offering fine-grained control over the synthesis of images. Nevertheless, expanding text-guided generation to high-resolution 3D images poses significant memory and anatomical detail-preserving challenges. Addressing the memory issue, we introduce a hierarchical scheme that uses a modified UNet architecture. We start by synthesizing low-resolution images conditioned on the text, serving as a foundation for subsequent generators for complete volumetric data. To ensure the anatomical plausibility of the generated samples, we provide further guidance by generating vascular, airway, and lobular segmentation masks in conjunction with the CT images. The model demonstrates the capability to use textual input and segmentation tasks to generate synthesized images. The results of comparative assessments indicate that our approach exhibits superior performance compared to the most advanced models based on GAN and diffusion techniques, especially in accurately retaining crucial anatomical features such as fissure lines, airways, and vascular structures. This innovation introduces novel possibilities. This study focuses on two main objectives: (1) the development of a method for creating images based on textual prompts and anatomical components, and (2) the capability to generate new images conditioning on anatomical elements. The advancements in image generation can be applied to enhance numerous downstream tasks.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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