原位诊疗一体化平台：在三维空间中联合高度局域化磁流体热疗、磁粒子成像与测温技术
In situ theranostic platform uniting highly localized magnetic fluid hyperthermia, magnetic particle imaging, and thermometry in 3D
AI总结：
本文首次在同一诊疗一体化平台中于三维空间内交错结合磁粒子成像、高度局域化磁流体热疗及基于MPI的测温安全控制，为肿瘤无创诊疗提供了新方案。
摘要：
在整个医学领域中，大量研究致力于寻求创伤更小、风险更低的治疗方式，其最终目标是实现无创治疗，尤其是在肿瘤性疾病方面。因此，将诊断与治疗方法整合在同一系统中的诊疗一体化平台引起了广泛关注，用以增强或替代侵入性外科手术、化学治疗和电离辐射干预。磁粒子成像（MPI）凭借其多功能示踪材料（超顺磁性氧化铁纳米粒子，SPIOs），为已建立的基于辐射的诊断模式提供了一种较新的替代方案。此外，MPI还提供了一个双模态诊疗一体化框架，允许使用完全相同的SPIOs将断层成像与治疗技术相结合。在本工作中，我们首次展示了基于MPI的成像、治疗（高度局域化磁流体热疗）和治疗安全控制（基于MPI的测温）在同一诊疗一体化平台中于全部三个空间维度上的交错组合。
英文摘要：
In all of medical profession a broad field of research is dedicated to seek less invasive and low-risk forms of therapy with the ultimate goal of non-invasive therapy, particularly in neoplasmic diseases. Theranostic platforms, combining diagnostic and therapeutic approaches within one system, have thus garnered interest to augment invasive surgical, chemical, and ionizing interventions. Magnetic particle imaging (MPI) offers, with its versatile tracer material (superparamagnetic iron oxide nanoparticles, SPIOs), a quite recent alternative to established radiation based diagnostic modalities. In addition, MPI lends a bimodal theranostic frame allowing to combine tomographic imaging with therapy techniques using the very same SPIOs. In this work, we show for the first time the interleaved combination of MPI-based imaging, therapy (highly localized magnetic fluid hyperthermia) and therapy safety control (MPI-based thermometry) within one theranostic platform in all three spatial dimensions.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
