通过中间复合物形成实现的生长与休眠之间的普适转变
Universal Transitions between Growth and Dormancy via Intermediate Complex Formation
AI总结:
本文通过数值研究含中间复合物形成的催化反应网络模型,揭示了细胞从指数生长到休眠的普适转变机制,即中间复合物积累导致反应堵塞,并伴随滞后现象。
摘要:
本文对一个由具有中间复合物形成的催化反应网络构成的简单细胞模型进行了数值研究。随着营养物质耗尽,从指数生长阶段到生长停滞的休眠阶段的转变伴随着滞后现象和生长恢复的滞后时间而发生。这种转变是由中间复合物的积累引起的,导致反应堵塞和组分多样化。这些性质在随机反应网络中具有普适性,相应的平均场模型的动力系统分析支持了这一结论。
英文摘要:
A simple cell model consisting of a catalytic reaction network with intermediate complex formation is numerically studied. As nutrients are depleted, the transition from the exponential growth phase to the growth-arrested dormant phase occurs along with hysteresis and a lag time for growth recovery. This transition is caused by the accumulation of intermediate complexes, leading to the jamming of reactions and the diversification of components. These properties are generic in random reaction networks, as supported by dynamical systems analyses of corresponding mean-field models.
机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。