空气等离子体灭活SARS-CoV-2的机制与安全性
Mechanisms and safety of air plasma inactivated SARS-CoV-2
AI总结：
本文研究空气冷大气等离子体直接灭活SARS-CoV-2的机制，发现其可消除病毒刺突并修饰蛋白体，并通过大鼠实验验证装置安全性，证明其可有效防止病毒传播与感染。
摘要：
冷大气等离子体（CAP）具有抗菌、抗肿瘤和抗病毒特性，但其潜在机制很少被清晰阐明。本工作采用以空气为供气气体的CAP直接灭活SARS-CoV-2。结果表明，等离子体处理后典型的SARS-CoV-2形态刺突消失，SARS-CoV-2的蛋白体被修饰。此外，我们还通过大鼠实验评估了该空气等离子体装置在模拟日常生活环境中的安全性。我们评估了大鼠的日常生理行为、体重、食物消耗、器官组织病理学、血液生化指标等。这些结果表明，空气等离子体装置是一种安全有效的手段，可防止病毒传播和感染。
英文摘要：
Cold atmospheric plasma (CAP) displays antimicrobial, antitumor, and antiviral properties, while the underlying mechanism is seldom clearly elucidated. In this work, we employed CAP with air-feeding gas to directly inactivate SARS-CoV-2. The results indicate that the typical SARS-CoV-2 morphological spikes disappeared after plasma treatment and the proteosomes of SRAS-CoV-2 were modified. In addition, we also evaluated the safety of the air plasma device in simulating daily life environments through rat experiments. We evaluated rats' daily physiological behavior, body weight, food consumption, organ histopathology, blood biochemical indicators, and so on. These results demonstrate air plasma device is a safe and effective mean prevents virus transmissions and infections.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
