健康社会决定因素本体（SDoHO）的系统化设计与评估
Systematic Design and Evaluation of Social Determinants of Health Ontology (SDoHO)
AI总结：
为解决健康社会决定因素（SDoH）的术语缺口，研究提出了标准化呈现SDoH因素及关系的本体SDoHO，经专家评审与数据评估效果良好，可为理解SDoH与健康的关联、推进健康公平提供支撑。
摘要：
健康社会决定因素（SDoH）对健康结局和福祉具有重大影响。应对SDoH是减少医疗保健不平等、将“疾病护理”体系转变为“健康促进”体系的关键。为解决SDoH术语缺口并更好地将相关要素融入前沿生物医学信息学，我们提出了健康社会决定因素本体SDoHO，它以标准化、可测量的方式呈现基础SDoH因素及其相互关系。该本体基于多种SDoH相关资源，对类、关系和约束进行了形式化建模。借助临床笔记数据和一项全国性调查开展的专家评审与覆盖度评估取得了令人满意的结果。SDoHO有望为全面理解SDoH与健康结局之间的关联奠定基础，并为实现人群层面的健康公平提供路径，发挥关键作用。
英文摘要：
Social determinants of health (SDoH) have a significant impact on health outcomes and well-being. Addressing SDoH is the key to reducing healthcare inequalities and transforming a "sick care" system into a "health promoting" system. To address the SDOH terminology gap and better embed relevant elements in advanced biomedical informatics, we propose an SDoH ontology (SDoHO), which represents fundamental SDoH factors and their relationships in a standardized and measurable way. The ontology formally models classes, relationships, and constraints based on multiple SDoH-related resources. Expert review and coverage evaluation, using clinical notes data and a national survey, showed satisfactory results. SDoHO could potentially play an essential role in providing a foundation for a comprehensive understanding of the associations between SDoH and health outcomes and providing a path toward health equity across populations.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
