PediaFlow小儿心室辅助装置定子叶片的自动CFD形状优化
Automated CFD shape optimization of stator blades for the PediaFlow pediatric ventricular assist device
摘要：
PediaFlow是一种用于新生儿和幼儿的微型混流心室辅助装置。PediaFlow有一个完全磁悬浮的转子，这提高了生物相容性，但转子长度的增加产生了一个长的环形通道，流体能量在那里损失。因此，提出了一组螺旋定子叶片紧接在叶轮级之后，以消除旋流并将动压头恢复为静压。对定子叶片进行了自动计算流体动力学（CFD）形状优化，以最大化1.5 LPM和16，000 RPM工作点处的压力恢复。此外，使用数值建模评估了对溶血和血栓形成的影响。优化算法倾向于更少的更长的叶片，而不是更大数量的短叶片。包角与轴向长度之比成为确保设计可行性的关键约束。最佳设计有2个叶片，在隔离级中产生73 mmHg的压力恢复。当重新引入完整流路的CFD模拟时，增加的定子级将泵扬程增加了46%，并将选定工作点处的泵效率从21.9%提高到25.7%。自动计算流体力学形状优化结合血液相容性的计算机模拟评价可以成为探索设计选择和告知早期开发过程的有效工具。
英文摘要：
PediaFlow is a miniature mixed-flow ventricular assist device for neonates and toddlers. PediaFlow has a fully magnetically levitated rotor which improves biocompatibility, but the increased length of the rotor creates a long annular passage where fluid energy is lost. Therefore, a set of helical stator blades was proposed immediately after the impeller stage to remove the swirling flow and recover the dynamic head as static pressure. Automated computational fluid dynamics (CFD) shape optimization of the stator blades was performed to maximize pressure recovery at the operating point of 1.5 LPM and 16,000 RPM. Additionally, the effect on hemolysis and thrombogenicity was assessed using numerical modeling. The optimization algorithm favored fewer blades of greater length over a larger number of short blades. The ratio of wrap angle to axial length emerged as a key constraint to ensure the viability of a design. The best design had 2 blades and generated 73 mmHg of pressure recovery in an isolated stage. When re-introduced to the CFD simulation of the complete flow path, the added stator stage increased the pump head by 46% and improved the pump efficiency from 21.9% to 25.7% at the selected operating point. Automated CFD shape optimization combined with in silico evaluation of hemocompatibility can be an effective tool for exploring design choices and informing early development process.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
