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arXiv 2204.03082cs.CV
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基于循环分割的无标记模态实例分割方法GAN

Instance Segmentation of Unlabeled Modalities via Cyclic Segmentation GAN

Harvard University(哈佛大学);Technical University of Munich(慕尼黑工业大学);MIT(麻省理工学院);University of Cambridge(剑桥大学);Donostia International Physics Center(多诺斯蒂亚国际物理中心);University of the Basque Country(巴斯克大学);Ikerbasque, Basque Foundation for Science(巴斯克科学基金会伊克巴斯克);HHMI(霍华德·休斯医学研究所);Boston College(波士顿学院)

Leander Lauenburg, Zudi Lin, Ruihan Zhang, Márcia dos Santos, Siyu Huang, Ignacio Arganda-Carreras, Edward S. Boyden, Hanspeter Pfister, Donglai Wei

摘要:

针对未标记成像模态的实例分割是一项具有挑战性但必不可少的任务,因为收集专家注释可能是昂贵且耗时的。现有的作品分割一个新的模式,通过部署一个预先训练的模型优化不同的训练数据或进行域转换和图像分割作为两个独立的步骤。在这项工作中,我们提出了一种新的循环分割生成对抗网络(CySGAN),进行图像翻译和实例分割联合使用一个统一的框架。除了图像翻译的CycleGAN损失和注释源域的监督损失外,我们还引入了额外的自监督和基于分割的对抗目标,通过利用未标记的目标域图像来提高模型性能。我们基准我们的方法上的任务,3D神经元细胞核分割与注释的电子显微镜(EM)图像和未标记的扩展显微镜(ExM)数据。我们的CySGAN优于预训练的通才模型和顺序进行图像翻译和分割的基线。我们的实现和新收集的,密集注释的ExM核数据集,名为NucExM,可在https://connectomics-bazaar.github.io/proj/CySGAN/index.html上获得。

英文摘要:

Instance segmentation for unlabeled imaging modalities is a challenging but essential task as collecting expert annotation can be expensive and time-consuming. Existing works segment a new modality by either deploying a pre-trained model optimized on diverse training data or conducting domain translation and image segmentation as two independent steps. In this work, we propose a novel Cyclic Segmentation Generative Adversarial Network (CySGAN) that conducts image translation and instance segmentation jointly using a unified framework. Besides the CycleGAN losses for image translation and supervised losses for the annotated source domain, we introduce additional self-supervised and segmentation-based adversarial objectives to improve the model performance by leveraging unlabeled target domain images. We benchmark our approach on the task of 3D neuronal nuclei segmentation with annotated electron microscopy (EM) images and unlabeled expansion microscopy (ExM) data. Our CySGAN outperforms both pretrained generalist models and the baselines that sequentially conduct image translation and segmentation. Our implementation and the newly collected, densely annotated ExM nuclei dataset, named NucExM, are available at https://connectomics-bazaar.github.io/proj/CySGAN/index.html.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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