arXivDaily arXiv每日学术速递 周一至周五更新
arXiv 2203.14044cs.LGeess.IV
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基于种群的fMRI分类的对比图学习

Contrastive Graph Learning for Population-based fMRI Classification

University of New South Wales(新南威尔士大学);Istanbul Technical University(伊斯坦布尔技术大学);Lehigh University(理海大学)

Xuesong Wang, Lina Yao, Islem Rekik, Yu Zhang

摘要:

对比自监督学习最近受益于fMRI分类与归纳偏见。它的弱标签依赖性防止了小型医学数据集的过度拟合,并解决了高组内方差。尽管如此,现有的对比方法仅在3D医学图像的像素级特征上生成相似对,而揭示关键认知信息的功能连接性则未得到充分探索。此外,现有的方法预测标签上的个人对比表示,而不认识相邻的信息,在患者组,而患者间的对比度可以作为一个相似性度量适合于基于人群的分类。因此,我们提出了基于人群的fMRI分类的对比功能连接图学习。功能连接图上的表示对于异质患者对是“排斥”的,而同质对则彼此“吸引”。然后更新一个动态的人口图,加强相似患者之间的联系,以进行分类。在多站点数据集ADHD200上的实验验证了该方法在各种指标上的优越性。我们首先将种群关系可视化,并利用潜在的亚型。

英文摘要:

Contrastive self-supervised learning has recently benefited fMRI classification with inductive biases. Its weak label reliance prevents overfitting on small medical datasets and tackles the high intraclass variances. Nonetheless, existing contrastive methods generate resemblant pairs only on pixel-level features of 3D medical images, while the functional connectivity that reveals critical cognitive information is under-explored. Additionally, existing methods predict labels on individual contrastive representation without recognizing neighbouring information in the patient group, whereas interpatient contrast can act as a similarity measure suitable for population-based classification. We hereby proposed contrastive functional connectivity graph learning for population-based fMRI classification. Representations on the functional connectivity graphs are "repelled" for heterogeneous patient pairs meanwhile homogeneous pairs "attract" each other. Then a dynamic population graph that strengthens the connections between similar patients is updated for classification. Experiments on a multi-site dataset ADHD200 validate the superiority of the proposed method on various metrics. We initially visualize the population relationships and exploit potential subtypes.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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