使用氦、氩和氮作为癌症治疗的供给气体的冷大气等离子体活化的去离子水
Cold atmospheric plasma activated deionized water using helium, argon, and nitrogen as feeding gas for cancer therapy
摘要：
含有活性氧（ROS）和活性氮（RNS）的等离子体活化培养基已作为间接治疗方法用于癌症治疗。在这里，我们报告了冷大气等离子体（CAP）激活去离子（DI）水使用氦气（He），氩气（Ar），氮气（N2）作为进料气体的癌症治疗。本实验研究了CAP活化去离子水在不同供气条件下的基本特性，并观察了三种溶液对乳腺癌细胞和胃癌细胞的作用。我们的研究结果表明，去离子水处理的CAP与氦进气有更强的影响凋亡的预培养的乳腺癌细胞和胃癌细胞。这些结果归因于使用He作为进料气体在CAP活化的DI水中产生的较高浓度的ROS。
英文摘要：
Plasma activated medium, containing reactive oxygen species (ROS) and reactive nitrogen species (RNS), has been used for cancer treatment as an indirect treatment method. Here we report cold atmospheric plasma (CAP) activated deionized (DI) water using helium (He), argon (Ar), and nitrogen (N2) as feeding gas for the cancer therapy. Basic characteristics of CAP activated DI water with different feeding gases were diagnosed and the effects of three solutions on the breast cancer cells and gastric cancer cells were also recorded. Our findings show that DI water treated by CAP with He feeding gas has a much stronger effect on apoptosis in precultured breast cancer cells and gastric cancer cells. These results are attributed to the higher concentration of ROS generated in CAP-activated DI water using He as feeding gas.
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