This paper evaluates synthetically generated healthcare data for biases and investigates the effect of fairness mitigation techniques on utility-fairness. Privacy laws limit access to health data such as Electronic Medical Records (EMRs) to preserve patient privacy. Albeit essential, these laws hinder research reproducibility. Synthetic data is a viable solution that can enable access to data similar to real healthcare data without privacy risks. Healthcare datasets may have biases in which certain protected groups might experience worse outcomes than others. With the real data having biases, the fairness of synthetically generated health data comes into question. In this paper, we evaluate the fairness of models generated on two healthcare datasets for gender and race biases. We generate synthetic versions of the dataset using a Generative Adversarial Network called HealthGAN, and compare the real and synthetic model's balanced accuracy and fairness scores. We find that synthetic data has different fairness properties compared to real data and fairness mitigation techniques perform differently, highlighting that synthetic data is not bias free.
KenSci Inc（KenSci公司）；University of Washington - Tacoma（华盛顿大学塔科马分校）；University of Washington - Bothell（华盛顿大学博塞尔分校）
Fairness in AI and machine learning systems has become a fundamental problem in the accountability of AI systems. While the need for accountability of AI models is near ubiquitous, healthcare in particular is a challenging field where accountability of such systems takes upon additional importance, as decisions in healthcare can have life altering consequences. In this paper we present preliminary results on fairness in the context of classification parity in healthcare. We also present some exploratory methods to improve fairness and choosing appropriate classification algorithms in the conte…
FairDiffusion: Enhancing Equity in Latent Diffusion Models via Fair Bayesian Perturbation
Harvard Medical School（哈佛医学院）；New York University（纽约大学）；New York University Abu Dhabi（纽约大学阿布扎比分校）；Harvard University（哈佛大学）；Broad Institute of MIT and Harvard（麻省理工学院与哈佛大学博德研究所）
Common fairness definitions in machine learning focus on balancing notions of disparity and utility. In this work, we study fairness in the context of risk disparity among sub-populations. We are interested in learning models that minimize performance discrepancies across sensitive groups without causing unnecessary harm. This is relevant to high-stakes domains such as healthcare, where non-maleficence is a core principle. We formalize this objective using Pareto frontiers, and provide analysis, based on recent works in fairness, to exemplify scenarios were perfect fairness might not be feasib…
Brigham and Women’s Hospital（布莱根妇女医院）；Harvard Medical School（哈佛医学院）；Broad Institute of Harvard and MIT（哈佛-麻省理工学院博德研究所）；Dana-Farber Cancer Institute（丹娜-法伯癌症研究所）；Boston University School of Medicine（波士顿大学医学院）；Massachusetts Institute of Technology（麻省理工学院）；Massachusetts General Hospital（麻省总医院）；Harvard University（哈佛大学）
In the current development and deployment of many artificial intelligence (AI) systems in healthcare, algorithm fairness is a challenging problem in delivering equitable care. Recent evaluation of AI models stratified across race sub-populations have revealed inequalities in how patients are diagnosed, given treatments, and billed for healthcare costs. In this perspective article, we summarize the intersectional field of fairness in machine learning through the context of current issues in healthcare, outline how algorithmic biases (e.g. - image acquisition, genetic variation, intra-observer l…
The recent release of large-scale healthcare datasets has greatly propelled the research of data-driven deep learning models for healthcare applications. However, due to the nature of such deep black-boxed models, concerns about interpretability, fairness, and biases in healthcare scenarios where human lives are at stake call for a careful and thorough examinations of both datasets and models. In this work, we focus on MIMIC-IV (Medical Information Mart for Intensive Care, version IV), the largest publicly available healthcare dataset, and conduct comprehensive analyses of dataset representati…
Stanford Center for Biomedical Informatics Research（斯坦福生物医学信息学研究中心）；Stanford University（斯坦福大学）
A growing body of work uses the paradigm of algorithmic fairness to frame the development of techniques to anticipate and proactively mitigate the introduction or exacerbation of health inequities that may follow from the use of model-guided decision-making. We evaluate the interplay between measures of model performance, fairness, and the expected utility of decision-making to offer practical recommendations for the operationalization of algorithmic fairness principles for the development and evaluation of predictive models in healthcare. We conduct an empirical case-study via development of …
Imputation Strategies Under Clinical Presence: Impact on Algorithmic Fairness
MRC Biostatistics Unit（MRC生物统计学单元）；University of Cambridge（剑桥大学）；The Alan Turing Institute（阿兰·图灵研究所）；McCombs School of Business（麦库姆斯商学院）；University of Texas at Austin（德克萨斯大学奥斯汀分校）；Rady School of Management（雷迪管理学院）；University of California, San Diego（加利福尼亚大学圣迭戈分校）
An ExplainableFair Framework for Prediction of Substance Use Disorder Treatment Completion
1 College of Computing；Informatics Drexel University, Philadelphia PA, USA Email: mml367,xw388,cc3859；2 Butler Center for Research Hazelden Betty Ford Foundation, Minnesota, USA Email: jbraughton
American University of the Middle East（美国中东大学）；University of Toronto（多伦多大学）
This paper presents a new approach to prevent transportation accidents and monitor driver's behavior using a healthcare AI system that incorporates fairness and ethics. Dangerous medical cases and unusual behavior of the driver are detected. Fairness algorithm is approached in order to improve decision-making and address ethical issues such as privacy issues, and to consider challenges that appear in the wild within AI in healthcare and driving. A healthcare professional will be alerted about any unusual activity, and the driver's location when necessary, is provided in order to enable the hea…
The use of machine learning to guide clinical decision making has the potential to worsen existing health disparities. Several recent works frame the problem as that of algorithmic fairness, a framework that has attracted considerable attention and criticism. However, the appropriateness of this framework is unclear due to both ethical as well as technical considerations, the latter of which include trade-offs between measures of fairness and model performance that are not well-understood for predictive models of clinical outcomes. To inform the ongoing debate, we conduct an empirical study to…
Debias-CLR: A Contrastive Learning Based Debiasing Method for Algorithmic Fairness in Healthcare Applications
Wright State University（莱特州立大学）；Cincinnati Children’s Hospital Medical Center（辛辛那提儿童医院医疗中心）；Kairos Research LLC（Kairos Research有限责任公司）；University of Illinois Chicago（伊利诺伊大学芝加哥分校）
University of Cambridge（剑桥大学）；MRC Biostatistics Unit, University of Cambridge（剑桥大学医学研究委员会生物统计组）；Sapienza University of Rome（罗马第一大学）；The Alan Turing Institute（阿兰·图灵研究所）；Technical University of Munich（慕尼黑工业大学）；Helmholtz Munich（亥姆霍兹慕尼黑中心）
While interest in the application of machine learning to improve healthcare has grown tremendously in recent years, a number of barriers prevent deployment in medical practice. A notable concern is the potential to exacerbate entrenched biases and existing health disparities in society. The area of fairness in machine learning seeks to address these issues of equity; however, appropriate approaches are context-dependent, necessitating domain-specific consideration. We focus on clinical trials, i.e., research studies conducted on humans to evaluate medical treatments. Clinical trials are a rela…
Fairness-aware Anomaly Detection via Fair Projection
The Chinese University of Hong Kong, Shenzhen（香港中文大学（深圳））；Shenzhen Research Institute of Big Data（深圳大数据研究院）；The Shenzhen Institute of Artificial Intelligence and Robotics for Society（深圳人工智能与机器人社会研究院）；The Guangdong Provincial Key Laboratory of Future Networks of Intelligence（广东省未来网络智能化重点实验室）
Beyond Static Knowledge Messengers: Towards Adaptive, Fair, and Scalable Federated Learning for Medical AI
Department of Computer Science and Software Engineering, Auburn University（计算机科学与软件工程系，阿伯丁大学）；Department of Information and Communication Technology, Bangladesh University of Professionals（信息与通信技术系，孟加拉国专业大学）；Mymensingh Medical College and Hospital（迈明辛医疗学院和医院）
Massachusetts Institute of Technology（麻省理工学院）；University of Toronto（多伦多大学）；Vector Institute（向量研究所）；Unity Health Toronto（多伦多团结健康医院）
Machine learning models in safety-critical settings like healthcare are often blackboxes: they contain a large number of parameters which are not transparent to users. Post-hoc explainability methods where a simple, human-interpretable model imitates the behavior of these blackbox models are often proposed to help users trust model predictions. In this work, we audit the quality of such explanations for different protected subgroups using real data from four settings in finance, healthcare, college admissions, and the US justice system. Across two different blackbox model architectures and fou…
Qatar Computing Research Institute（卡塔尔计算研究所）；University of Gabes（加贝斯大学）；Sidra Medicine（西德拉医院）
Patient no-shows is a major burden for health centers leading to loss of revenue, increased waiting time and deteriorated health outcome. Developing machine learning (ML) models for the prediction of no -shows could help addressing this important issue. It is crucial to consider fair ML models for no-show prediction in order to ensure equality of opportunity in accessing healthcare services. In this wo rk, we are interested in developing deep learning models for no-show prediction based on tabular data while ensuring fairness properties. Our baseline model, TabNet, uses on attentive feature tr…
FedFiTS: Fitness-Selected, Slotted Client Scheduling for Trustworthy Federated Learning in Healthcare AI
Department of Computer Science University of the Western Cape（计算机科学系，西开普敦大学）；Department of Computer Science Missouri University of Science and Technology（计算机科学系，密苏里科学与技术大学）
Xi’an Jiaotong-Liverpool University（西交利物浦大学）；Xi’an Jiaotong University（西安交通大学）；University of Oklahoma（俄克拉荷马大学）；University of Washington（华盛顿大学）
Scoring systems, as a type of predictive model, have significant advantages in interpretability and transparency and facilitate quick decision-making. As such, scoring systems have been extensively used in a wide variety of industries such as healthcare and criminal justice. However, the fairness issues in these models have long been criticized, and the use of big data and machine learning algorithms in the construction of scoring systems heightens this concern. In this paper, we propose a general framework to create fairness-aware, data-driven scoring systems. First, we develop a social welfa…
When Does Multimodal Learning Help in Healthcare? A Benchmark on EHR and Chest X-Ray Fusion
Department of Computer Science（计算机科学系）；Hong Kong Baptist University（香港 Baptist 大学）；Division of Artificial Intelligence（人工智能 division）；Lingnan University（Lingnan 大学）；School of Nursing（护理学院）；The Hong Kong Polytechnic University（香港理工大学）
We study the problem of learning fair prediction models for unseen test sets distributed differently from the train set. Stability against changes in data distribution is an important mandate for responsible deployment of models. The domain adaptation literature addresses this concern, albeit with the notion of stability limited to that of prediction accuracy. We identify sufficient conditions under which stable models, both in terms of prediction accuracy and fairness, can be learned. Using the causal graph describing the data and the anticipated shifts, we specify an approach based on featur…
Can I trust my fake data -- A comprehensive quality assessment framework for synthetic tabular data in healthcare
University of Oslo（奥斯陆大学）；DNV AS（挪威船级社）；Cancer Registry of Norway（挪威癌症登记处）；Oslo University Hospital（奥斯陆大学医院）；UiT The Arctic University of Norway（挪威北极大学）
Mila – Quebec AI Institute（米拉-魁北克人工智能研究所）；University of Washington Tacoma（华盛顿大学塔科马分校）；Ghent University（根特大学）
Machine learning (ML) has become prominent in applications that directly affect people's quality of life, including in healthcare, justice, and finance. ML models have been found to exhibit discrimination based on sensitive attributes such as gender, race, or disability. Assessing if an ML model is free of bias remains challenging to date, and by definition has to be done with sensitive user characteristics that are subject of anti-discrimination and data protection law. Existing libraries for fairness auditing of ML models offer no mechanism to protect the privacy of the audit data. We presen…
FairFML: Fair Federated Machine Learning with a Case Study on Reducing Gender Disparities in Cardiac Arrest Outcome Prediction
Duke-NUS Medical School（杜克-新加坡国立大学医学院）；Duke University（杜克大学）；Kyoto University（京都大学）；Singapore Health Services（新加坡保健服务）；Singapore General Hospital（新加坡中央医院）；NUS Artificial Intelligence Institute（新加坡国立大学人工智能研究所）；National University of Singapore（新加坡国立大学）
