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arXiv 2201.06255q-bio.GN
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FastRemap:一种在基因组组装之间快速重映射读段的工具

FastRemap: A Tool for Quickly Remapping Reads between Genome Assemblies

Jeremie S. Kim, Can Firtina, Meryem Banu Cavlak, Damla Senol Cali, Can Alkan, Onur Mutlu

AI总结:

FastRemap是一种快速高效的读段重映射工具,相比CrossMap平均加速6.47倍,内存消耗降低至80.7%,适用于基因组组装间的读段重映射。

摘要:

基因组读段数据集可以使用多种工具(例如常用的CrossMap工具)从一个参考基因组快速高效地重映射到另一个相似的参考基因组(例如,在两个参考版本或两个相似物种之间)。随着可用基因组数据集和参考基因组的爆炸式增长,高性能重映射工具对于跟上基因组组装和分析的计算需求将更加重要。我们提供了FastRemap,一种用于在基因组组装之间重映射读段的快速高效工具。与最先进的重映射工具CrossMap相比,FastRemap提供了高达7.82倍的加速(平均6.47倍),并且峰值内存消耗低至61.7%(平均80.7%)。FastRemap使用C++编写。源代码和用户手册可在github.com/CMU-SAFARI/FastRemap免费获取。Docker镜像可在https://hub.docker.com/r/alkanlab/fast获取。也可在Bioconda的https://anaconda.org/bioconda/fastremap-bio获取。

英文摘要:

A genome read data set can be quickly and efficiently remapped from one reference to another similar reference (e.g., between two reference versions or two similar species) using a variety of tools, e.g., the commonly-used CrossMap tool. With the explosion of available genomic data sets and references, high-performance remapping tools will be even more important for keeping up with the computational demands of genome assembly and analysis. We provide FastRemap, a fast and efficient tool for remapping reads between genome assemblies. FastRemap provides up to a 7.82$\times$ speedup (6.47$\times$, on average) and uses as low as 61.7% (80.7%, on average) of the peak memory consumption compared to the state-of-the-art remapping tool, CrossMap. FastRemap is written in C++. The source code and user manual are freely available at: github.com/CMU-SAFARI/FastRemap. Docker image available at: https://hub.docker.com/r/alkanlab/fast. Also available in Bioconda at: https://anaconda.org/bioconda/fastremap-bio.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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