智利的结直肠癌趋势:一个社会经济不平等的拉丁美洲国家
Colorectal cancer trends in Chile: a Latin-American country with marked socioeconomic inequities
摘要:
结直肠癌是世界上第三大常见的恶性肿瘤。在一些建立了筛查计划的国家,其发病率和死亡率有所下降,生存率有所提高。目标:为了获得关于智利CRC流行病学的可靠数据,我们分析了过去十年的趋势以及可观察因素对生存率的影响,包括CRC治疗获得的明确保证(GES计划)。使用了卫生部和国家统计研究所公布的公开数据。从死亡率和出院登记处获得数据,使个人的后续行动成为可能。计算粗和年龄标准化发病率和死亡率,并通过构建Kaplan-Meier曲线研究个体生存率。最后,建立Cox统计模型来估计可观察因素的影响。
英文摘要:
Colorectal cancer (CRC) is the third most frequent malignant disease in the world. In some countries with established screening programs, its incidence and mortality have decreased, and survival has improved. AIMS: To obtain reliable data about the epidemiology of CRC in Chile, we analyzed the trends in the last ten years and the influence of observable factors on survival, including explicit guarantees in CRC treatment access (GES program). Publicly available data published by the Health Ministry and National Institute of Statistics were used. Data were obtained from registries of mortality and hospital discharges, making follow-up of the individuals possible. Crude and age-standardized incidence and mortality rates were calculated, and individual survival was studied by constructing Kaplan-Meier curves. Finally, a Cox statistical model was established to estimate the impact of the observable factors.
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