This paper presents the use of Multi-Agent Reinforcement Learning (MARL) to perform navigation in 3D anatomical volumes from medical imaging. We utilize Neural Style Transfer to create synthetic Computed Tomography (CT) agent gym environments and assess the generalization capabilities of our agents to clinical CT volumes. Our framework does not require any labelled clinical data and integrates easily with several image translation techniques, enabling cross modality applications. Further, we solely condition our agents on 2D slices, breaking grounds for 3D guidance in much more difficult imaging modalities, such as ultrasound imaging. This is an important step towards user guidance during the acquisition of standardised diagnostic view planes, improving diagnostic consistency and facilitating better case comparison.
Indian Institute of Technology Madras（印度理工学院马德拉斯分校）；Healthcare Technology Innovation Centre（医疗技术创新中心）；Sri Rama Chandra Institute of Higher Education and Research（斯里·拉马·钱德拉高等教育与研究所）
MRI entails a great amount of cost, time and effort for the generation of all the modalities that are recommended for efficient diagnosis and treatment planning. Recent advancements in deep learning research show that generative models have achieved substantial improvement in the aspects of style transfer and image synthesis. In this work, we formulate generating the missing MR modality from existing MR modalities as an imputation problem using style transfer. With a multiple-to-one mapping, we model a network that accommodates domain specific styles in generating the target image. We analyse …
Southern University of Science and Technology（南方科技大学）；The University of Hong Kong（香港大学）
Various deep learning models have been developed to segment anatomical structures from medical images, but they typically have poor performance when tested on another target domain with different data distribution. Recently, unsupervised domain adaptation methods have been proposed to alleviate this so-called domain shift issue, but most of them are designed for scenarios with relatively small domain shifts and are likely to fail when encountering a large domain gap. In this paper, we propose DCDA, a novel cross-modality unsupervised domain adaptation framework for tasks with large domain shif…
Modality-Agnostic Style Transfer for Holistic Feature Imputation
Pohang University of Science and Technology（浦项科技大学）；University of North Carolina at Chapel Hill（北卡罗来纳大学教堂山分校）；University of North Carolina at Greensboro（北卡罗来纳大学格林斯伯勒分校）
UC Santa Barbara（加州大学圣巴巴拉分校）；UC Santa Cruz（加州大学圣克鲁兹分校）；UC San Diego（加州大学圣地亚哥分校）；Google（谷歌）
One of the most challenging topics in Natural Language Processing (NLP) is visually-grounded language understanding and reasoning. Outdoor vision-and-language navigation (VLN) is such a task where an agent follows natural language instructions and navigates a real-life urban environment. Due to the lack of human-annotated instructions that illustrate intricate urban scenes, outdoor VLN remains a challenging task to solve. This paper introduces a Multimodal Text Style Transfer (MTST) learning approach and leverages external multimodal resources to mitigate data scarcity in outdoor navigation ta…
Deep learning (DL)-based models have demonstrated good performance in medical image segmentation. However, the models trained on a known dataset often fail when performed on an unseen dataset collected from different centers, vendors and disease populations. In this work, we present a random style transfer network to tackle the domain generalization problem for multi-vendor and center cardiac image segmentation. Style transfer is used to generate training data with a wider distribution/ heterogeneity, namely domain augmentation. As the target domain could be unknown, we randomly generate a mod…
Texas A&M University（德克萨斯A&M大学）；The University of Texas at Austin（德克萨斯大学奥斯汀分校）；Adobe Research（Adobe研究院）
Generating font glyphs of consistent style from one or a few reference glyphs, i.e., font completion, is an important task in topographical design. As the problem is more well-defined than general image style transfer tasks, thus it has received interest from both vision and machine learning communities. Existing approaches address this problem as a direct image-to-image translation task. In this work, we innovate to explore the generation of font glyphs as 2D graphic objects with the graph as an intermediate representation, so that more intrinsic graphic properties of font styles can be captu…
Image-to-image translation and voice conversion enable the generation of a new facial image and voice while maintaining some of the semantics such as a pose in an image and linguistic content in audio, respectively. They can aid in the content-creation process in many applications. However, as they are limited to the conversion within each modality, matching the impression of the generated face and voice remains an open question. We propose a cross-modal style transfer framework called XFaVoT that jointly learns four tasks: image translation and voice conversion tasks with audio or image guida…
Multiscale Structure-Guided Latent Diffusion for Multimodal MRI Translation
Computer Science and Engineering, Northeastern University, Shenyang, China（东北大学计算机科学与工程系，沈阳，中国）；Key Laboratory of Intelligent Computing in Medical Image of Ministry of Education, Northeastern University, Shenyang, China（教育部医学图像智能计算重点实验室，东北大学，沈阳，中国）；National Frontiers Science Center for Industrial Intelligence and Systems Optimization, Shenyang, China（工业智能与系统优化国家级前沿科学中心，沈阳，中国）；Amii, University of Alberta, Edmonton, Alberta, Canada（阿尔伯塔大学阿米人工智能研究所，埃德蒙顿，阿尔伯塔，加拿大）；AiShiWeiLai AI Research, Beijing, China（人工智能研究（北京）有限公司，北京，中国）
We propose a domain adaptation method, MoDA, which adapts a pretrained embodied agent to a new, noisy environment without ground-truth supervision. Map-based memory provides important contextual information for visual navigation, and exhibits unique spatial structure mainly composed of flat walls and rectangular obstacles. Our adaptation approach encourages the inherent regularities on the estimated maps to guide the agent to overcome the prevalent domain discrepancy in a novel environment. Specifically, we propose an efficient learning curriculum to handle the visual and dynamics corruptions …
Recent learning-based image fusion methods have marked numerous progress in pre-registered multi-modality data, but suffered serious ghosts dealing with misaligned multi-modality data, due to the spatial deformation and the difficulty narrowing cross-modality discrepancy. To overcome the obstacles, in this paper, we present a robust cross-modality generation-registration paradigm for unsupervised misaligned infrared and visible image fusion (IVIF). Specifically, we propose a Cross-modality Perceptual Style Transfer Network (CPSTN) to generate a pseudo infrared image taking a visible image as i…
Domains such as logo synthesis, in which the data has a high degree of multi-modality, still pose a challenge for generative adversarial networks (GANs). Recent research shows that progressive training (ProGAN) and mapping network extensions (StyleGAN) enable both increased training stability for higher dimensional problems and better feature separation within the embedded latent space. However, these architectures leave limited control over shaping the output of the network, which is an undesirable trait in the case of logo synthesis. This paper explores a conditional extension to the StyleGA…
University of California, Davis（加州大学戴维斯分校）；University of San Francisco Data Institute（旧金山大学数据研究所）；Wicklow AI in Medicine Research Initiative（威克洛医学人工智能研究计划）；University of Texas, San Antonio Health（德克萨斯大学圣安东尼奥健康分校）
MUSE is a novel slide-free imaging technique for histological examination of tissues that can serve as an alternative to traditional histology. In order to bridge the gap between MUSE and traditional histology, we aim to convert MUSE images to resemble authentic hematoxylin- and eosin-stained (H&E) images. We evaluated four models: a non-machine-learning-based color-mapping unmixing-based tool, CycleGAN, DualGAN, and GANILLA. CycleGAN and GANILLA provided visually compelling results that appropriately transferred H&E style and preserved MUSE content. Based on training an automated critic on re…
Karlsruhe Institute of Technology（卡尔斯鲁厄理工学院）；Istanbul Technical University（伊斯坦布尔理工大学）
In this paper, we explore the correlation between different visual biometric modalities. For this purpose, we present an end-to-end deep neural network model that learns a mapping between the biometric modalities. Namely, our goal is to generate a frontal face image of a subject given his/her ear image as the input. We formulated the problem as a paired image-to-image translation task and collected datasets of ear and face image pairs from the Multi-PIE and FERET datasets to train our GAN-based models. We employed feature reconstruction and style reconstruction losses in addition to adversaria…
Memorial Sloan Kettering Cancer Center（纪念斯隆-凯特琳癌症中心）
Our contribution is a unified cross-modality feature disentagling approach for multi-domain image translation and multiple organ segmentation. Using CT as the labeled source domain, our approach learns to segment multi-modal (T1-weighted and T2-weighted) MRI having no labeled data. Our approach uses a variational auto-encoder (VAE) to disentangle the image content from style. The VAE constrains the style feature encoding to match a universal prior (Gaussian) that is assumed to span the styles of all the source and target modalities. The extracted image style is converted into a latent style sc…
HuTuMotion: Human-Tuned Navigation of Latent Motion Diffusion Models with Minimal Feedback
Northwest A&F University（西北农林科技大学）；Tencent AI Lab（腾讯AI实验室）；The University of Melbourne（墨尔本大学）；Mohamed bin Zayed University of Artificial Intelligence（穆罕默德·本·扎耶德人工智能大学）
Department of Biomedical Engineering, Yale University（耶鲁大学生物医学工程系）；Department of Radiology & Biomedical Imaging, Yale School of Medicine（耶鲁大学医学院放射科与生物医学成像系）；Department of Electrical Engineering, Yale University（耶鲁大学电气工程系）；Department of Statistics & Data Science, Yale University（耶鲁大学统计与数据科学系）；Yale School of Medicine（耶鲁大学医学院）；Yale University（耶鲁大学）
A deep learning model trained on some labeled data from a certain source domain generally performs poorly on data from different target domains due to domain shifts. Unsupervised domain adaptation methods address this problem by alleviating the domain shift between the labeled source data and the unlabeled target data. In this work, we achieve cross-modality domain adaptation, i.e. between CT and MRI images, via disentangled representations. Compared to learning a one-to-one mapping as the state-of-art CycleGAN, our model recovers a many-to-many mapping between domains to capture the complex c…
Unsupervised domain adaptation (UDA) methods have shown their promising performance in the cross-modality medical image segmentation tasks. These typical methods usually utilize a translation network to transform images from the source domain to target domain or train the pixel-level classifier merely using translated source images and original target images. However, when there exists a large domain shift between source and target domains, we argue that this asymmetric structure could not fully eliminate the domain gap. In this paper, we present a novel deep symmetric architecture of UDA for …
Colorization involves the synthesis of colors on a target image while preserving structural content as well as the semantics of the target image. This is a well-explored problem in 2D with many state-of-the-art solutions. We propose a novel deep learning-based approach for the colorization of 3D medical volumes. Our system is capable of directly mapping the colors of a 2D photograph to a 3D MRI volume in real-time, producing a high-fidelity color volume suitable for photo-realistic visualization. Since this work is first of its kind, we discuss the full pipeline in detail and the challenges th…
