作为生物学相变的铁凋亡I：无血管性和血管性肿瘤生长
Ferroptosis as a Biological Phase Transition I: avascular and vascular tumor growth
摘要：
在此，我们讨论了一个网络模型的铁凋亡无血管和血管肿瘤生长的基础上，我们以前提出的框架。Chillance，ferroptosis应被视为一个一级相变的特点是超临界Andronov-Hopf分岔，极限环的出现。作为控制参数，氧化的PUFA片段的人口的增加，涉及逆Feigenbaum，（一个级联的鞍焦点Shilnikov的分叉）的情况下，这导致在稳定的动力学和复杂性的降低。
英文摘要：
Herewith we discuss a network model of the ferroptosis avascular and vascular tumor growth based on our previous proposed framework. Chiefly, ferroptosis should be viewed as a first order phase transition characterized by a supercritical Andronov Hopf bifurcation, with the emergence of limit cycle. The increase of the population of the oxidized PUFA fragments, take as the control parameter, involves an inverse Feigenbaum, (a cascade of saddle foci Shilnikov's bifurcations) scenario, which results in the stabilization of the dynamics and in a decrease of complexity.
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