Analysis of cardiac ultrasound images is commonly performed in routine clinical practice for quantification of cardiac function. Its increasing automation frequently employs deep learning networks that are trained to predict disease or detect image features. However, such models are extremely data-hungry and training requires labelling of many thousands of images by experienced clinicians. Here we propose the use of contrastive learning to mitigate the labelling bottleneck. We train view classification models for imbalanced cardiac ultrasound datasets and show improved performance for views/classes for which minimal labelled data is available. Compared to a naive baseline model, we achieve an improvement in F1 score of up to 26% in those views while maintaining state-of-the-art performance for the views with sufficiently many labelled training observations.
Lawrence Berkeley National Lab（劳伦斯伯克利国家实验室）；California Institute for Quantitative Biosciences (QB3)（加利福尼亚定量生物科学研究所）；University of California at Berkeley（加州大学伯克利分校）；Beth Israel Deaconess Medical Center（贝斯以色列女执事医疗中心）；Cardiovascular Research Institute（心血管研究所）；University of California, San Francisco（加州大学旧金山分校）
Echocardiography is essential to modern cardiology. However, human interpretation limits high throughput analysis, limiting echocardiography from reaching its full clinical and research potential for precision medicine. Deep learning is a cutting-edge machine-learning technique that has been useful in analyzing medical images but has not yet been widely applied to echocardiography, partly due to the complexity of echocardiograms' multi view, multi modality format. The essential first step toward comprehensive computer assisted echocardiographic interpretation is determining whether computers c…
Tufts University（塔夫茨大学）；CVAI Solutions（CVAI解决方案公司）；Tufts Medical Center（塔夫茨医疗中心）
Semi-supervised image classification has shown substantial progress in learning from limited labeled data, but recent advances remain largely untested for clinical applications. Motivated by the urgent need to improve timely diagnosis of life-threatening heart conditions, especially aortic stenosis, we develop a benchmark dataset to assess semi-supervised approaches to two tasks relevant to cardiac ultrasound (echocardiogram) interpretation: view classification and disease severity classification. We find that a state-of-the-art method called MixMatch achieves promising gains in heldout accura…
S2MNet: Speckle-To-Mesh Net for Three-Dimensional Cardiac Morphology Reconstruction via Echocardiogram
Department of Statistics, University of Georgia（佐治亚大学统计学系）；Department of Statistics, Havard University（哈佛大学统计学系）；Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing Hospital（中国医学科学院老年医学研究所）
ETH Zürich（苏黎世联邦理工学院）；University Children’s Hospital Regensburg (KUNO)（雷根斯堡大学儿童医院（KUNO））
Pulmonary hypertension (PH) in newborns and infants is a complex condition associated with several pulmonary, cardiac, and systemic diseases contributing to morbidity and mortality. Therefore, accurate and early detection of PH is crucial for successful management. Using echocardiography, the primary diagnostic tool in pediatrics, human assessment is both time-consuming and expertise-demanding, raising the need for an automated approach. In this work, we present an interpretable multi-view video-based deep learning approach to predict PH for a cohort of 194 newborns using echocardiograms. We u…
EchoingECG: An Electrocardiogram Cross-Modal Model for Echocardiogram Tasks
Peter Munk Cardiac Centre, University Health Network (UHN)（彼得·默克心脏中心，大学健康网络）；Department of Medical Biophysics, UofT（医学生物物理学系）；Ted Rogers Centre for Heart Research, UHN（泰德·罗杰斯心脏病研究中心，大学健康网络）；Department of Computer Science, University of Toronto (UofT)（计算机科学系，多伦多大学）；Toronto General Hospital Research Institute, UHN（多伦多总医院研究 institute）；Department of Medical Imaging, UofT（医学影像学系）；Vector Institute, Toronto（向量研究所）
Automated interpretation of congenital heart disease from multi-view echocardiograms
Capital Medical University（首都医科大学）；Carnegie Mellon University（卡内基梅隆大学）；Harvard University（哈佛大学）；Harvard Medical School（哈佛医学院）；Beijing Children’s Hospital（北京儿童医院）；National Center for Children’s Health（国家儿童健康中心）；Harbin Engineering University（哈尔滨工程大学）；National Research Institute for Family Planning（国家计划生育委员会科学技术研究所）
Standard views in two-dimensional echocardiography are well established but the quality of acquired images are highly dependent on operator skills and are assessed subjectively. This study is aimed at providing an objective assessment pipeline for echocardiogram image quality by defining a new set of domain-specific quality indicators. Consequently, image quality assessment can thus be automated to enhance clinical measurements, interpretation, and real-time optimization. We have developed deep neural networks for the automated assessment of echocardiographic frame which were randomly sampled …
Multi-view feature extraction is an efficient approach for alleviating the issue of dimensionality in highdimensional multi-view data. Contrastive learning (CL), which is a popular self-supervised learning method, has recently attracted considerable attention. In this study, we propose a novel multi-view feature extraction method based on triple contrastive heads, which combines the sample-, recovery- , and feature-level contrastive losses to extract the sufficient yet minimal subspace discriminative information in compliance with information bottleneck principle. In MFETCH, we construct the f…
Beijing Jiaotong University（北京交通大学）；Harbin Institute of Technology, Shenzhen（哈尔滨工业大学（深圳））
Multi-view representation learning has developed rapidly over the past decades and has been applied in many fields. However, most previous works assumed that each view is complete and aligned. This leads to an inevitable deterioration in their performance when encountering practical problems such as missing or unaligned views. To address the challenge of representation learning on partially aligned multi-view data, we propose a new cross-view graph contrastive learning framework, which integrates multi-view information to align data and learn latent representations. Compared with current appro…
In this paper, we propose an augmentation-free graph contrastive learning framework, namely ACTIVE, to solve the problem of partial multi-view clustering. Notably, we suppose that the representations of similar samples (i.e., belonging to the same cluster) and their multiply views features should be similar. This is distinct from the general unsupervised contrastive learning that assumes an image and its augmentations share a similar representation. Specifically, relation graphs are constructed using the nearest neighbours to identify existing similar samples, then the constructed inter-instan…
EchoPrime: A Multi-Video View-Informed Vision-Language Model for Comprehensive Echocardiography Interpretation
Cedars-Sinai Medical Center（西达赛奈医疗中心）；University of California Los Angeles（加州大学洛杉矶分校）；Stanford University（斯坦福大学）；University of California, San Francisco（加州大学旧金山分校）；San Francisco Veterans Affairs Medical Center（旧金山退伍军人事务医疗中心）
Inria（法国国家信息与自动化研究所）；Université Côte d’Azur（蔚蓝海岸大学）；European Systems Integration（欧洲系统集成公司）
Recent self-supervised contrastive learning provides an effective approach for unsupervised person re-identification (ReID) by learning invariance from different views (transformed versions) of an input. In this paper, we incorporate a Generative Adversarial Network (GAN) and a contrastive learning module into one joint training framework. While the GAN provides online data augmentation for contrastive learning, the contrastive module learns view-invariant features for generation. In this context, we propose a mesh-based view generator. Specifically, mesh projections serve as references toward…
Institute of Data Science and Intelligent Decision Support（数据科学与智能决策支持研究所）；Frontiers Science Center for Smart High-speed Railway System（智慧高铁系统前沿科学中心）；Beijing Jiaotong University（北京交通大学）
Multi-view representation learning is essential for many multi-view tasks, such as clustering and classification. However, there are two challenging problems plaguing the community: i)how to learn robust multi-view representation from mass unlabeled data and ii) how to balance the view consistency and the view specificity. To this end, in this paper, we proposed a hybrid contrastive fusion algorithm to extract robust view-common representation from unlabeled data. Specifically, we found that introducing an additional representation space and aligning representations on this space enables the m…
National University of Singapore（新加坡国立大学）；Tsinghua University（清华大学）；Alibaba Group（阿里巴巴集团）
Recent self-supervised contrastive learning methods greatly benefit from the Siamese structure that aims at minimizing distances between positive pairs. For high performance Siamese representation learning, one of the keys is to design good contrastive pairs. Most previous works simply apply random sampling to make different crops of the same image, which overlooks the semantic information that may degrade the quality of views. In this work, we propose ContrastiveCrop, which could effectively generate better crops for Siamese representation learning. Firstly, a semantic-aware object localizati…
Trunk-branch Contrastive Network with Multi-view Deformable Aggregation for Multi-view Action Recognition
Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences（中国科学院深圳先进技术研究院）；University of Chinese Academy of Sciences（中国科学院大学）；School of Mechanical Engineering and Automation, Harbin Institute of Technology at Shenzhen（哈尔滨工业大学（深圳）机械工程与自动化学院）
Peking University（北京大学）；Microsoft Research Asia（微软亚洲研究院）
Contrastive learning between different views of the data achieves outstanding success in the field of self-supervised representation learning and the learned representations are useful in broad downstream tasks. Since all supervision information for one view comes from the other view, contrastive learning approximately obtains the minimal sufficient representation which contains the shared information and eliminates the non-shared information between views. Considering the diversity of the downstream tasks, it cannot be guaranteed that all task-relevant information is shared between views. The…
Self-supervised skeleton-based action recognition with contrastive learning has attracted much attention. Recent literature shows that data augmentation and large sets of contrastive pairs are crucial in learning such representations. In this paper, we found that directly extending contrastive pairs based on normal augmentations brings limited returns in terms of performance, because the contribution of contrastive pairs from the normal data augmentation to the loss get smaller as training progresses. Therefore, we delve into hard contrastive pairs for contrastive learning. Motivated by the su…
Transformed Multi-view 3D Shape Features with Contrastive Learning
Instituto de Ciências Matemáticas e de Computação (ICMC), Universidade de São Paulo (USP), São Carlos, SP, Brazil（数学与计算机科学研究所（ICMC），圣保罗大学（USP），圣卡洛斯，SP，巴西）
Qiannan Normal University for Nationalities（黔南民族师范学院）；Guizhou University（贵州大学）；Peng Cheng Laboratory（鹏城实验室）；Guangxi Normal University（广西师范大学）
In this paper, we propose a Global-Supervised Contrastive loss and a view-aware-based post-processing (VABPP) method for the field of vehicle re-identification. The traditional supervised contrastive loss calculates the distances of features within the batch, so it has the local attribute. While the proposed Global-Supervised Contrastive loss has new properties and has good global attributes, the positive and negative features of each anchor in the training process come from the entire training set. The proposed VABPP method is the first time that the view-aware-based method is used as a post-…
Harbin Institute of Technology, Shenzhen（哈尔滨工业大学（深圳））；Sun Yat-sen University（中山大学）；Pengcheng Laboratory（鹏城实验室）
In recent years, multi-view multi-label learning has aroused extensive research enthusiasm. However, multi-view multi-label data in the real world is commonly incomplete due to the uncertain factors of data collection and manual annotation, which means that not only multi-view features are often missing, and label completeness is also difficult to be satisfied. To deal with the double incomplete multi-view multi-label classification problem, we propose a deep instance-level contrastive network, namely DICNet. Different from conventional methods, our DICNet focuses on leveraging deep neural net…
University of Electronic Science and Technology of China（电子科技大学）；Harbin Institute of Technology Shenzhen（哈尔滨工业大学（深圳））；Pengcheng Lab（鹏城实验室）
The goal of few-shot classification is to classify new categories with few labeled examples within each class. Nowadays, the excellent performance in handling few-shot classification problems is shown by metric-based meta-learning methods. However, it is very hard for previous methods to discriminate the fine-grained sub-categories in the embedding space without fine-grained labels. This may lead to unsatisfactory generalization to fine-grained subcategories, and thus affects model interpretation. To tackle this problem, we introduce the contrastive loss into few-shot classification for learni…
Shenzhen International Graduate School, Tsinghua University（清华大学深圳国际研究生院）；Research Institute of Tsinghua, Pearl River Delta（清华大学珠三角研究院）
Learning-based multi-view stereo (MVS) methods have made impressive progress and surpassed traditional methods in recent years. However, their accuracy and completeness are still struggling. In this paper, we propose a new method to enhance the performance of existing networks inspired by contrastive learning and feature matching. First, we propose a Contrast Matching Loss (CML), which treats the correct matching points in depth-dimension as positive sample and other points as negative samples, and computes the contrastive loss based on the similarity of features. We further propose a Weighted…
Generative Diffusion Contrastive Network for Multi-View Clustering
Zhejiang Lab（浙江实验室）；Hong Kong University of Science and Technology（香港科技大学）；University of Science and Technology of China（中国科学技术大学）；Huazhong University of Science and Technology（华中科技大学）
The Hong Kong Polytechnic University（香港理工大学）；Research Institute for Smart Ageing, The Hong Kong Polytechnic University（香港理工大学智慧老龄研究学院）；Nantong University（南通大学）
The prediction of adaptive radiation therapy (ART) prior to radiation therapy (RT) for nasopharyngeal carcinoma (NPC) patients is important to reduce toxicity and prolong the survival of patients. Currently, due to the complex tumor micro-environment, a single type of high-resolution image can provide only limited information. Meanwhile, the traditional softmax-based loss is insufficient for quantifying the discriminative power of a model. To overcome these challenges, we propose a supervised multi-view contrastive learning method with an additive margin (MMCon). For each patient, four medical…
Recent Vision-Language Pre-trained (VLP) models based on dual encoder have attracted extensive attention from academia and industry due to their superior performance on various cross-modal tasks and high computational efficiency. They attempt to learn cross-modal representation using contrastive learning on image-text pairs, however, the built inter-modal correlations only rely on a single view for each modality. Actually, an image or a text contains various potential views, just as humans could capture a real-world scene via diverse descriptions or photos. In this paper, we propose ERNIE-ViL …
Tianjin University（天津大学）；Key Research Center for Surface Monitoring and Analysis of Cultural Relics (SMARC), State Administration of Cultural Heritage, China（中国国家文物局文物表面监测与分析重点研究中心）；University of South Carolina（南卡罗来纳大学）
Skeleton-based human action recognition has been drawing more interest recently due to its low sensitivity to appearance changes and the accessibility of more skeleton data. However, even the 3D skeletons captured in practice are still sensitive to the viewpoint and direction gave the occlusion of different human-body joints and the errors in human joint localization. Such view variance of skeleton data may significantly affect the performance of action recognition. To address this issue, we propose in this paper a new view-invariant representation learning approach, without any manual action …
Rutgers University（罗格斯大学）；Google Research（谷歌研究院）；Caltech（加州理工学院）；University of Delaware（特拉华大学）
We introduce a novel representation learning method to disentangle pose-dependent as well as view-dependent factors from 2D human poses. The method trains a network using cross-view mutual information maximization (CV-MIM) which maximizes mutual information of the same pose performed from different viewpoints in a contrastive learning manner. We further propose two regularization terms to ensure disentanglement and smoothness of the learned representations. The resulting pose representations can be used for cross-view action recognition. To evaluate the power of the learned representations, in…
Bosch Center for Artificial Intelligence（博世人工智能中心）；University of Bonn（波恩大学）
Self-supervised video representation methods typically focus on the representation of temporal attributes in videos. However, the role of stationary versus non-stationary attributes is less explored: Stationary features, which remain similar throughout the video, enable the prediction of video-level action classes. Non-stationary features, which represent temporally varying attributes, are more beneficial for downstream tasks involving more fine-grained temporal understanding, such as action segmentation. We argue that a single representation to capture both types of features is sub-optimal, a…
Huazhong Univerisity of Science and Technology（华中科技大学）；Tsinghua University（清华大学）
Discriminative representation is crucial for the association step in multi-object tracking. Recent work mainly utilizes features in single or neighboring frames for constructing metric loss and empowering networks to extract representation of targets. Although this strategy is effective, it fails to fully exploit the information contained in a whole trajectory. To this end, we propose a strategy, namely multi-view trajectory contrastive learning, in which each trajectory is represented as a center vector. By maintaining all the vectors in a dynamically updated memory bank, a trajectory-level c…
Self-supervised learning based on instance discrimination has shown remarkable progress. In particular, contrastive learning, which regards each image as well as its augmentations as an individual class and tries to distinguish them from all other images, has been verified effective for representation learning. However, pushing away two images that are de facto similar is suboptimal for general representation. In this paper, we propose a hierarchical semantic alignment strategy via expanding the views generated by a single image to \textbf{Cross-samples and Multi-level} representation, and mod…
Shenzhen University（深圳大学）；Harbin Institute of Technology (Shenzhen)（哈尔滨工业大学（深圳））
A two-stage training paradigm consisting of sequential pre-training and meta-training stages has been widely used in current few-shot learning (FSL) research. Many of these methods use self-supervised learning and contrastive learning to achieve new state-of-the-art results. However, the potential of contrastive learning in both stages of FSL training paradigm is still not fully exploited. In this paper, we propose a novel contrastive learning-based framework that seamlessly integrates contrastive learning into both stages to improve the performance of few-shot classification. In the pre-train…
University of Utah（犹他大学）；Scientific Computing and Imaging Institute, University of Utah（犹他大学科学计算与成像研究所）；Huntsman Cancer Institute, University of Utah（犹他大学亨茨曼癌症研究所）
We propose a novel semi-supervised learning approach for classification of histopathology images. We employ strong supervision with patch-level annotations combined with a novel co-training loss to create a semi-supervised learning framework. Co-training relies on multiple conditionally independent and sufficient views of the data. We separate the hematoxylin and eosin channels in pathology images using color deconvolution to create two views of each slide that can partially fulfill these requirements. Two separate CNNs are used to embed the two views into a joint feature space. We use a contr…
Huazhong University of Science and Technology（华中科技大学）；National University of Singapore（新加坡国立大学）；Alibaba Group（阿里巴巴集团）
The central idea of contrastive learning is to discriminate between different instances and force different views from the same instance to share the same representation. To avoid trivial solutions, augmentation plays an important role in generating different views, among which random cropping is shown to be effective for the model to learn a generalized and robust representation. Commonly used random crop operation keeps the distribution of the difference between two views unchanged along the training process. In this work, we show that adaptively controlling the disparity between two augment…
Self-supervised contrastive learning has demonstrated great potential in learning visual representations. Despite their success in various downstream tasks such as image classification and object detection, self-supervised pre-training for fine-grained scenarios is not fully explored. We point out that current contrastive methods are prone to memorizing background/foreground texture and therefore have a limitation in localizing the foreground object. Analysis suggests that learning to extract discriminative texture information and localization are equally crucial for fine-grained self-supervis…
