We propose an atlas-based method to segment the intracochlear anatomy (ICA) in the post-implantation CT (Post-CT) images of cochlear implant (CI) recipients that preserves the point-to-point correspondence between the meshes in the atlas and the segmented volumes. To solve this problem, which is challenging because of the strong artifacts produced by the implant, we use a pair of co-trained deep networks that generate dense deformation fields (DDFs) in opposite directions. One network is tasked with registering an atlas image to the Post-CT images and the other network is tasked with registering the Post-CT images to the atlas image. The networks are trained using loss functions based on voxel-wise labels, image content, fiducial registration error, and cycle-consistency constraint. The segmentation of the ICA in the Post-CT images is subsequently obtained by transferring the predefined segmentation meshes of the ICA in the atlas image to the Post-CT images using the corresponding DDFs generated by the trained registration networks. Our model can learn the underlying geometric features of the ICA even though they are obscured by the metal artifacts. We show that our end-to-end network produces results that are comparable to the current state of the art (SOTA) that relies on a two-steps approach that first uses conditional generative adversarial networks to synthesize artifact-free images from the Post-CT images and then uses an active shape model-based method to segment the ICA in the synthetic images. Our method requires a fraction of the time needed by the SOTA, which is important for end-user acceptance.
AREPAS: Anomaly Detection in Fine-Grained Anatomy with Reconstruction-Based Semantic Patch-Scoring
Computational Imaging Research Lab, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna(医学影像与影像引导治疗系计算成像研究实验室,维也纳医学大学);Comprehensive Center for Artificial Intelligence in Medicine, Medical University of Vienna(医学人工智能综合中心,维也纳医学大学)
4DLoG: Generative Modeling of Neurodegenerative Brain Anatomy with 4D Longitudinal Diffusion Model
Department of Electrical and Computer Engineering(电气与计算机工程系);Department of Radiology(放射学系);Department of Electrical and Computer Engineering, Department of Computer Science(电气与计算机工程系、计算机科学系)
University of Maryland(马里兰大学);PAII Inc.(PAII公司);Alibaba Group DAMO Academy(阿里巴巴集团达摩院);Xpeng Motors(小鹏汽车);Ping An Technology(平安科技);Chang Gung Memorial Hospital(长庚纪念医院)
Osteoporosis is a common chronic metabolic bone disease often under-diagnosed and under-treated due to the limited access to bone mineral density (BMD) examinations, e.g. via Dual-energy X-ray Absorptiometry (DXA). This paper proposes a method to predict BMD from Chest X-ray (CXR), one of the most commonly accessible and low-cost medical imaging examinations. Our method first automatically detects Regions of Interest (ROIs) of local CXR bone structures. Then a multi-ROI deep model with transformer encoder is developed to exploit both local and global information in the chest X-ray image for ac…
F2PASeg: Feature Fusion for Pituitary Anatomy Segmentation in Endoscopic Surgery
1Centre for Artificial Intelligence;Robotics, Hong Kong Institute of Science \& Innovation, Chinese Academy of Sciences 2The University of Hong Kong 3Peking Union Medical College Hospital, Chinese Academy of Medical Science
Radboud University Medical Center(拉德堡德大学医学中心);Radboud Institute for Health Sciences(拉德堡德健康科学研究所)
Early detection improves prognosis in pancreatic ductal adenocarcinoma (PDAC) but is challenging as lesions are often small and poorly defined on contrast-enhanced computed tomography scans (CE-CT). Deep learning can facilitate PDAC diagnosis, however current models still fail to identify small (<2cm) lesions. In this study, state-of-the-art deep learning models were used to develop an automatic framework for PDAC detection, focusing on small lesions. Additionally, the impact of integrating surrounding anatomy was investigated. CE-CT scans from a cohort of 119 pathology-proven PDAC patients an…
SurgPointTransformer: Vertebrae Shape Completion with RGB-D Data
Research in Orthopedic Computer Science, University Hospital Balgrist, University of Zürich(苏黎世大学、巴尔格里斯特大学医院骨科计算机科学研究所);Balgrist University Hospital, University of Zurich(苏黎世大学巴尔格里斯特大学医院)
Computer-aided diagnosis (CAD) has long become an integral part of radiological management of breast disease, facilitating a number of important clinical applications, including quantitative assessment of breast density and early detection of malignancies based on X-ray mammography. Common to such applications is the need to automatically discriminate between breast tissue and adjacent anatomy, with the latter being predominantly represented by pectoralis major (or pectoral muscle). Especially in the case of mammograms acquired in the mediolateral oblique (MLO) view, the muscle is easily confu…
Vanderbilt University(范德堡大学);Vanderbilt University Medical Center(范德堡大学医学中心)
Cochlear implants (CIs) are a standard treatment for patients who experience severe to profound hearing loss. Recent studies have shown that hearing outcome is correlated with intra-cochlear anatomy and electrode placement. Our group has developed image-guided CI programming (IGCIP) techniques that use image analysis methods to both segment the inner ear structures in pre- or post-implantation CT images and localize the CI electrodes in post-implantation CT images. This permits to assist audiologists with CI programming by suggesting which among the contacts should be deactivated to reduce ele…
Christian Medical College Ludhiana(卢迪亚纳基督教医学院);Pacific Neuroscience Institute(太平洋神经科学研究所)
A stroke occurs when an artery in the brain ruptures and bleeds or when the blood supply to the brain is cut off. Blood and oxygen cannot reach the brain's tissues due to the rupture or obstruction resulting in tissue death. The Middle cerebral artery (MCA) is the largest cerebral artery and the most commonly damaged vessel in stroke. The quick onset of a focused neurological deficit caused by interruption of blood flow in the territory supplied by the MCA is known as an MCA stroke. Alberta stroke programme early CT score (ASPECTS) is used to estimate the extent of early ischemic changes in pa…
The onset of rheumatic diseases such as rheumatoid arthritis is typically subclinical, which results in challenging early detection of the disease. However, characteristic changes in the anatomy can be detected using imaging techniques such as MRI or CT. Modern imaging techniques such as chemical exchange saturation transfer (CEST) MRI drive the hope to improve early detection even further through the imaging of metabolites in the body. To image small structures in the joints of patients, typically one of the first regions where changes due to the disease occur, a high resolution for the CEST …
AtlasSeg: Atlas Prior Guided Dual-U-Net for Cortical Segmentation in Fetal Brain MRI
College of Biomedical Engineering & Instrument Science, Zhejiang University(浙江大学生物医学工程与仪器科学学院);Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences(中国医学科学院北京医院国家老年医学中心老年医学研究所);Shandong Provincial Hospital Affiliated to Shandong First Medical University(山东第一医科大学附属山东省立医院);State Key Lab of CAD&CG, Zhejiang University(浙江大学CAD&CG国家重点实验室)
Background: Regarding the importance of right diagnosis in medical applications, various methods have been exploited for processing medical images solar. The method of segmentation is used to analyze anal to miscall structures in medical imaging. Objective: This study describes a new method for brain Magnetic Resonance Image (MRI) segmentation via a novel algorithm based on genetic and regional growth. Methods: Among medical imaging methods, brains MRI segmentation is important due to the high contrast of non-intrusive soft tissue and high spatial resolution. Size variations of brain tissues a…
Instituto de Aplicaciones de las Tecnologías de la Información y de las Comunicaciones Avanzadas (ITACA), Universitat Politècnica de València(瓦伦西亚理工大学先进信息技术与通信应用研究所 (ITACA));CNRS(法国国家科学研究中心);Univ. Bordeaux(波尔多大学);Bordeaux INP(波尔多国立高等工程技术学校);Universitat de Valencia(瓦伦西亚大学);University Valencia(瓦伦西亚大学);EPHE(巴黎高等研究实践学院);CHU de Bordeaux(波尔多大学医院中心);Institut des Maladies Neurodégénératives(神经退行性疾病研究所);CEA Saclay(法国原子能和替代能源委员会萨克雷);Instituto de Automática e Informática Industrial, Universitat Politècnica de València(瓦伦西亚大学工业自动化与计算机研究所);Hospital Universitario y Politécnico La Fe(拉菲大学综合医院);Fundación para el Fomento de la Investigación Sanitario y Biomédica de la Comunidad Valenciana(瓦伦西亚社区健康与生物医学研究促进基金会)