Sensitivity analysis for measurement error can be applied in the absence of validation data by means of regression calibration and simulation-extrapolation. These have not been compared for this purpose. A simulation study was conducted comparing the performance of regression calibration and simulation-extrapolation in a multivariable model. The performance of the two methods was evaluated in terms of bias, mean squared error (MSE) and confidence interval coverage, for ranging reliability of the error-prone measurement (0.2-0.9), sample size (125-1,000), number of replicates (2-10), and R-squared (0.03-0.75). It was assumed that no validation data were available about the error-free measures, while measurement error variance was correctly estimated. In various scenarios, regression calibration was unbiased while simulation-extrapolation was biased: median bias was 1.4% (interquartile range (IQR): 0.8;2%), and -12.8% (IQR: -13.2;-11.0%), respectively. A small gain in efficiency was observed for simulation-extrapolation (median MSE: 0.005, IQR: 0.004;0.006) versus regression calibration (median MSE: 0.006, IQR: 0.004;0.007). Confidence interval coverage was at the nominal level of 95% for regression calibration, and smaller than 95% for simulation-extrapolation (median coverage: 92%, IQR: 85;94%). In the absence of validation data, the use of regression calibration is recommended for sensitivity analysis for measurement error.
Extrapolation of extreme covariates in generalized additive regression using extreme-value theory
INRAE(法国国家农业食品环境研究院);University of Geneva(日内瓦大学);Univ Brest, CNRS UMR 6205, Laboratoire de Mathématiques de Bretagne Atlantique(布雷斯特大学、法国国家科学研究中心第6205联合研究单位、布列塔尼大西洋数学实验室)
Conformalized Quantile Regression and Minimax Limits of Fixed-Score Calibration under Known Covariate Shift
HSE University(高等经济大学);Lomonosov Moscow State University(罗蒙诺索夫莫斯科国立大学);Laboratoire de Recherche d’EPITA(EPITA研究实验室);University of Duisburg-Essen(杜伊斯堡-埃森大学);Mohamed bin Zayed University of Artificial Intelligence (MBZUAI)(穆罕默德·本·扎耶德人工智能大学(MBZUAI))
Scalable regression calibration approaches to correcting measurement error in multi-level generalized functional linear regression models with heteroscedastic measurement errors
Reliable Real-Time Value at Risk Estimation via Quantile Regression Forest with Conformal Calibration
Institute of Statistics and Big Data, Renmin University of China(统计与大数据研究院,中国人民大学);Department of Decision Analytics and Operations, City University of Hong Kong(决策分析与运营部门,香港城市大学);School of Information, Renmin University of China(信息学院,中国人民大学)
Calibration of prediction rules for life-time outcomes using prognostic Cox regression survival models and multiple imputations to account for missing predictor data with cross-validatory assessment