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arXiv 2106.00637q-bio.NC
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大脑时空模式研究的蓝图

A Blueprint for the Study of the Brain's Spatiotemporal Patterns

Emmanuelle Tognoli, Daniela Benites, J. A. Scott Kelso

摘要:

像大脑这样的器官的功能来自于其组成部分之间的相互作用。此外,这种相互作用在时间上不是一成不变的,而是以一系列模式展开的,从而使大脑能够适应不断变化的外部和内部环境。这就需要一个能够研究大脑组成部分之间模式化时空相互作用的框架。一个理论和方法的框架来研究大脑的协调动力学。在这里,我们提出了一个工具集,旨在破译连续动态的电生理数据及其关系(dys-)功能。了解大脑模式的时空组织及其与行为,认知和临床相关变量的关联是神经科学和生物启发工程领域的一个重要挑战。希望这样一个全面的框架不仅能揭示人类行为和人类思维,还能帮助理解越来越多的与大脑连接障碍有关的病理学。

英文摘要:

The functioning of an organ such as the brain emerges from interactions between its constituent parts. Further, this interaction is not immutable in time but rather unfolds in a succession of patterns, thereby allowing the brain to adapt to constantly changing exterior and interior milieus. This calls for a framework able to study patterned spatiotemporal interactions between components of the brain. A theoretical and methodological framework is developed to study the brain's coordination dynamics. Here we present a toolset designed to decipher the continuous dynamics of electrophysiological data and its relation to (dys-) function. Understanding the spatiotemporal organization of brain patterns and their association with behavioral, cognitive and clinically-relevant variables is an important challenge for the fields of neuroscience and biologically-inspired engineering. It is hoped that such a comprehensive framework will shed light not only on human behavior and the human mind but also help in understanding the growing number of pathologies that are linked to disorders of brain connectivity.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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