以纳米金为模板的DNA折纸链状结构
DNA Origami Catenanes Templated by Gold Nanoparticles
摘要：
机械联锁分子是拓扑化学领域的重大突破，推动了分子机械的蓬勃发展。作为互锁分子的典型实例，索烃包括像链中的连接件一样彼此穿过的大环。受过渡金属模板链烷合成方法的启发，本工作展示了以金纳米颗粒为模板的DNA折纸链烷的分级组装。成功地产生了含有两个、三个或四个互锁环的DNA折纸链烷。特别地，通过释放互连的金纳米颗粒，可以使各个索烃内的折纸环相对于彼此自由。这项工作将为基于DNA的分子结构的丰富进展奠定基础，这些分子结构具有独特的结构可编程性和明确的拓扑结构。
英文摘要：
Mechanically interlocked molecules have marked a breakthrough in the field of topological chemistry and boosted the vigorous development of molecular machinery. As an archetypal example of the interlocked molecules, catenanes comprise macrocycles that are threaded through one another like links in a chain. Inspired by the transition metal-templated approach of catenanes synthesis, the hierarchical assembly of DNA origami catenanes templated by gold nanoparticles is demonstrated in this work. DNA origami catenanes, which contain two, three or four interlocked rings are successfully created. In particular, the origami rings within the individual catenanes can be set free with respect to one another by releasing the interconnecting gold nanoparticles. This work will set the basis for rich progress toward DNA-based molecular architectures with unique structural programmability and well-defined topology.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
