arXivDaily arXiv每日学术速递 周一至周五更新
arXiv 2104.11567q-bio.BMcond-mat.softphysics.bio-ph
收藏

DNA的oxDNA模型入门:何时使用、如何模拟以及如何解释结果

A primer on the oxDNA model of DNA: When to use it, how to simulate it and how to interpret the results

Aditya Sengar, Thomas E. Ouldridge, Oliver Henrich, Lorenzo Rovigatti, Petr Sulc

摘要:

DNA的oxDNA模型在生物学、生物物理学和纳米技术中有着广泛的应用。它目前通过两个独立的开源软件包提供。在这里,我们提出了一套清晰的记录范例模拟,同时提供了一个介绍模拟模型,并审查模型的基本属性。我们概述了如何模拟结果可以解释方面-和饲料到我们的理解-不太详细的模型,在更大的长度尺度上运行,并提供指导是否与oxDNA模拟系统是值得的。

英文摘要:

The oxDNA model of DNA has been applied widely to systems in biology, biophysics and nanotechnology. It is currently available via two independent open source packages. Here we present a set of clearly-documented exemplar simulations that simultaneously provide both an introduction to simulating the model, and a review of the model's fundamental properties. We outline how simulation results can be interpreted in terms of -- and feed into our understanding of -- less detailed models that operate at larger length scales, and provide guidance on whether simulating a system with oxDNA is worthwhile.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

↑