用于同时控制低和高Refractive Index微粒的散斑镊
Speckle Tweezers for Simultaneous Controlling of Low and High Refractive Index Micro-particles
摘要:
操纵悬浮在流体介质中的微米和纳米级颗粒是现代纳米技术的定义目标之一。散斑镊(ST)通过引入随机分布的光场,已被用于对折射率高于其介质的微粒的布朗运动施加可检测的限制。事实上,与周期性电位相比,ST代表了更广泛的可能性,可用于此类任务。在这里,我们将ST的有用性扩展到低折射率微粒。高强度区域将这种颗粒排斥到较低强度区域中使得它们被局部限制,并且可以通过改变散斑图案的平均晶粒强度和尺寸来调节限制。聚苯乙烯和脂质体的实验验证的程序。此外,我们表明ST可以用于纳米粒子(NP)负载的脂质体。有趣的是,装载NP的脂质体和空脂质体与ST的不同相互作用使得能够使用相同的斑点图案集体操纵它们的混合物,这可以通过在装载NP的脂质体中包括NP上的电泳力来解释。我们的结果之间的不同行为的空和非空囊泡可能打开一个新的窗口,控制集体运输的药物微容器及其广泛的应用在软物质。
英文摘要:
Manipulation of micro and nanoscale particles suspended in a fluidic medium is one among the defining goals of modern nanotechnology. Speckle tweezers (ST) by incorporating randomly distributed light fields have been used to apply detectable limits on the Brownian motion of micro-particles with refractive indices higher than their medium. Indeed, compared to periodic potentials, ST represents a wider possibility to be operated for such tasks. Here, we extend the usefulness of ST into low index micro-particles. Repelling of such particles by high intensity regions into lower intensity regions makes them to be locally confined, and the confinement can be tuned by changing the average grain intensity and size of the speckle patterns. Experiments on polystyrenes and liposomes validate the procedure. Moreover, we show that ST can be used to nano-particle (NP)-loaded liposomes. Interestingly, the different interactions of NP-loaded and empty liposomes with ST enables collective manipulation of their mixture using the same speckle pattern, which may be explained by inclusion of the photophoretic forces on NPs in NP-loaded liposomes. Our results on the different behavior between empty and non-empty vesicles may open a new window on controlling collective transportation of drug micro-containers along with its wide applications in soft matter.
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