不确定性传播和灵敏度分析：来自眼科数学虚拟模拟器的结果
Uncertainty propagation and sensitivity analysis: results from the Ocular Mathematical Virtual Simulator
摘要：
我们提出了一个不确定性传播研究和灵敏度分析与眼部数学虚拟模拟器，计算和数学模型，预测血液动力学和生物力学在人眼。在这篇文章中，我们专注于眼内压，椎板后组织压力和全身血压对眼后组织血管的影响。基于物理的模型与基于实验的随机输入相结合，使我们能够更好地了解生理系统，同时考虑驱动机制和数据可变性。
英文摘要：
We propose an uncertainty propagation study and a sensitivity analysis with the Ocular Mathematical Virtual Simulator, a computational and mathematical model that predicts the hemodynamics and biomechanics within the human eye. In this contribution, we focus on the effect of intraocular pressure, retrolaminar tissue pressure and systemic blood pressure on the ocular posterior tissue vasculature. The combination of a physically-based model with experiments-based stochastic input allows us to gain a better understanding of the physiological system, accounting both for the driving mechanisms and the data variability.
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