We propose a method to facilitate exploration and analysis of new large data sets. In particular, we give an unsupervised deep learning approach to learning a latent representation that captures semantic similarity in the data set. The core idea is to use data augmentations that preserve semantic meaning to generate synthetic examples of elements whose feature representations should be close to one another.
We demonstrate the utility of our method applied to nano-scale electron microscopy data, where even relatively small portions of animal brains can require terabytes of image data. Although supervised methods can be used to predict and identify known patterns of interest, the scale of the data makes it difficult to mine and analyze patterns that are not known a priori. We show the ability of our learned representation to enable query by example, so that if a scientist notices an interesting pattern in the data, they can be presented with other locations with matching patterns. We also demonstrate that clustering of data in the learned space correlates with biologically-meaningful distinctions. Finally, we introduce a visualization tool and software ecosystem to facilitate user-friendly interactive analysis and uncover interesting biological patterns. In short, our work opens possible new avenues in understanding of and discovery in large data sets, arising in domains such as EM analysis.
University of Sydney（悉尼大学）；University of New South Wales（新南威尔士大学）；Brigham and Women’s Hospital（布莱根妇女医院）；Harvard Medical School（哈佛医学院）；University of Pittsburgh（匹兹堡大学）；Microsoft Corporation（微软公司）
Unsupervised domain adaptation (UDA) for nuclei instance segmentation is important for digital pathology, as it alleviates the burden of labor-intensive annotation and domain shift across datasets. In this work, we propose a Cycle Consistency Panoptic Domain Adaptive Mask R-CNN (CyC-PDAM) architecture for unsupervised nuclei segmentation in histopathology images, by learning from fluorescence microscopy images. More specifically, we first propose a nuclei inpainting mechanism to remove the auxiliary generated objects in the synthesized images. Secondly, a semantic branch with a domain discrimi…
University of Copenhagen（哥本哈根大学）；Rigshospitalet（哥本哈根大学国立医院）
Generative models such as Generative Adversarial Networks (GANs) and Variational Autoencoders (VAEs) play an increasingly important role in medical image analysis. The latent spaces of these models often show semantically meaningful directions corresponding to human-interpretable image transformations. However, until now, their exploration for medical images has been limited due to the requirement of supervised data. Several methods for unsupervised discovery of interpretable directions in GAN latent spaces have shown interesting results on natural images. This work explores the potential of a…
BenevolentAI（BenevolentAI公司）；Big Data Institute, University of Oxford（牛津大学大数据研究所）
Biological imaging data are often partially confounded or contain unwanted variability. Examples of such phenomena include variable lighting across microscopy image captures, stain intensity variation in histological slides, and batch effects for high throughput drug screening assays. Therefore, to develop "fair" models which generalise well to unseen examples, it is crucial to learn data representations that are insensitive to nuisance factors of variation. In this paper, we present a strategy based on adversarial training, capable of learning unsupervised representations invariant to confoun…
Unsupervised cell segmentation by fast Gaussian Processes
Department of Statistics and Applied Probability, University of California, Santa Barbara, CA（统计与应用概率系，加州大学圣芭芭拉分校）；Department of Electrical and Computer Engineering, University of California, Santa Barbara, CA（电气与计算机工程系，加州大学圣芭芭拉分校）
Indian Institute of Technology（印度理工学院）；University of Alberta（阿尔伯塔大学）；Hospital Universitario Puerta de Hierro（普埃塔德耶罗大学医院）；Government Medical College（政府医学院）；Sree Chitra Tirunal Institute of Medical Sciences and Technology（斯里奇特拉图鲁纳尔医学科学与技术研究所）；Bhagwan Mahaveer Jain Hospital（巴格万马哈维尔耆那医院）
The COVID-19 pandemic has highlighted the need for a tool to speed up triage in ultrasound scans and provide clinicians with fast access to relevant information. The proposed video-summarization technique is a step in this direction that provides clinicians access to relevant key-frames from a given ultrasound scan (such as lung ultrasound) while reducing resource, storage and bandwidth requirements. We propose a new unsupervised reinforcement learning (RL) framework with novel rewards that facilitates unsupervised learning avoiding tedious and impractical manual labelling for summarizing ultr…
Imperial College London（帝国理工学院）；University College London（伦敦大学学院）
We present the first unsupervised deep learning method for pollen analysis using bright-field microscopy. Using a modest dataset of 650 images of pollen grains collected from honey, we achieve family level identification of pollen. We embed images of pollen grains into a low-dimensional latent space and compare Euclidean and Riemannian metrics on these spaces for clustering. We propose this system for automated analysis of pollen and other microscopic biological structures which have only small or unlabelled datasets available.
Google Research（谷歌研究院）；Fondazione Human Technopole（人类技术城基金会）
Image denoising and artefact removal are complex inverse problems admitting multiple valid solutions. Unsupervised diversity restoration, that is, obtaining a diverse set of possible restorations given a corrupted image, is important for ambiguity removal in many applications such as microscopy where paired data for supervised training are often unobtainable. In real world applications, imaging noise and artefacts are typically hard to model, leading to unsatisfactory performance of existing unsupervised approaches. This work presents an interpretable approach for unsupervised and diverse imag…
EPFL（洛桑联邦理工学院）；Technical University of Munich（慕尼黑工业大学）；Boğaziçi University（博阿齐奇大学）
Recent research has shown that it is possible to find interpretable directions in the latent spaces of pre-trained Generative Adversarial Networks (GANs). These directions enable controllable image generation and support a wide range of semantic editing operations, such as zoom or rotation. The discovery of such directions is often done in a supervised or semi-supervised manner and requires manual annotations which limits their use in practice. In comparison, unsupervised discovery allows finding subtle directions that are difficult to detect a priori. In this work, we propose a contrastive le…
Australian National University（澳大利亚国立大学）；Data61, CSIRO（联邦科学与工业研究组织数据61研究所）
Unsupervised point cloud completion aims to infer the whole geometry of a partial object observation without requiring partial-complete correspondence. Differing from existing deterministic approaches, we advocate generative modeling based unsupervised point cloud completion to explore the missing correspondence. Specifically, we propose a novel framework that performs completion by transforming a partial shape encoding into a complete one using a latent transport module, and it is designed as a latent-space energy-based model (EBM) in an encoder-decoder architecture, aiming to learn a probabi…
One task that is often discussed in a computer vision is the mapping of an image from one domain to a corresponding image in another domain known as image-to-image translation. Currently there are several approaches solving this task. In this paper, we present an enhancement of the UNIT framework that aids in removing its main drawbacks. More specifically, we introduce an additional adversarial discriminator on the latent representation used instead of VAE, which enforces the latent space distributions of both domains to be similar. On MNIST and USPS domain adaptation tasks, this approach grea…
École Centrale de Nantes（南特中央理工学院）；Laboratoire des Sciences du Numérique de Nantes（南特数字科学实验室）；CNRS（法国国家科学研究中心）
This paper addresses the domain shift problem for segmentation. As a solution, we propose OLVA, a novel and lightweight unsupervised domain adaptation method based on a Variational Auto-Encoder (VAE) and Optimal Transport (OT) theory. Thanks to the VAE, our model learns a shared cross-domain latent space that follows a normal distribution, which reduces the domain shift. To guarantee valid segmentations, our shared latent space is designed to model the shape rather than the intensity variations. We further rely on an OT loss to match and align the remaining discrepancy between the two domains …
Action recognition and detection in the context of long untrimmed video sequences has seen an increased attention from the research community. However, annotation of complex activities is usually time consuming and challenging in practice. Therefore, recent works started to tackle the problem of unsupervised learning of sub-actions in complex activities. This paper proposes a novel approach for unsupervised sub-action learning in complex activities. The proposed method maps both visual and temporal representations to a latent space where the sub-actions are learnt discriminatively in an end-to…
Yandex（扬德克斯）；National Research University Higher School of Economics（国立研究型大学高等经济学院）
The latent spaces of GAN models often have semantically meaningful directions. Moving in these directions corresponds to human-interpretable image transformations, such as zooming or recoloring, enabling a more controllable generation process. However, the discovery of such directions is currently performed in a supervised manner, requiring human labels, pretrained models, or some form of self-supervision. These requirements severely restrict a range of directions existing approaches can discover. In this paper, we introduce an unsupervised method to identify interpretable directions in the la…
We propose a framework for the completely unsupervised learning of latent object properties from their interactions: the perception-prediction network (PPN). Consisting of a perception module that extracts representations of latent object properties and a prediction module that uses those extracted properties to simulate system dynamics, the PPN can be trained in an end-to-end fashion purely from samples of object dynamics. The representations of latent object properties learned by PPNs not only are sufficient to accurately simulate the dynamics of systems comprised of previously unseen object…
Technion - Israel Institute of Technology（以色列理工学院）
We propose a new representation of visual data that disentangles object position from appearance. Our method, termed Deep Latent Particles (DLP), decomposes the visual input into low-dimensional latent ``particles'', where each particle is described by its spatial location and features of its surrounding region. To drive learning of such representations, we follow a VAE-based approach and introduce a prior for particle positions based on a spatial-softmax architecture, and a modification of the evidence lower bound loss inspired by the Chamfer distance between particles. We demonstrate that ou…
The Chinese University of Hong Kong（香港中文大学）；Samsung Research Institute China - Beijing (SRC-B)（三星中国研究院-北京（SRC-B））
Unsupervised point cloud completion aims at estimating the corresponding complete point cloud of a partial point cloud in an unpaired manner. It is a crucial but challenging problem since there is no paired partial-complete supervision that can be exploited directly. In this work, we propose a novel framework, which learns a unified and structured latent space that encoding both partial and complete point clouds. Specifically, we map a series of related partial point clouds into multiple complete shape and occlusion code pairs and fuse the codes to obtain their representations in the unified l…
Dedan Kimathi University of Technology（德丹·基马蒂理工大学）；Strasbourg University（斯特拉斯堡大学）；CNRS（法国国家科学研究中心）
Archiving large sets of medical or cell images in digital libraries may require ordering randomly scattered sets of image data according to specific criteria, such as the spatial extent of a specific local color or contrast content that reveals different meaningful states of a physiological structure, tissue, or cell in a certain order, indicating progression or recession of a pathology, or the progressive response of a cell structure to treatment. Here we used a Self Organized Map (SOM)-based, fully automatic and unsupervised, classification procedure described in our earlier work and applied…
State Key Laboratory of Virtual Reality Technology and Systems（虚拟现实技术与系统全国重点实验室）；School of Computer Science and Engineering, Beihang University（北京航空航天大学计算机学院）
Many real world vision tasks, such as reflection removal from a transparent surface and intrinsic image decomposition, can be modeled as single image layer separation. However, this problem is highly ill-posed, requiring accurately aligned and hard to collect triplet data to train the CNN models. To address this problem, this paper proposes an unsupervised method that requires no ground truth data triplet in training. At the core of the method are two assumptions about data distributions in the latent spaces of different layers, based on which a novel unsupervised layer separation pipeline can…
What defines a visual style? Fashion styles emerge organically from how people assemble outfits of clothing, making them difficult to pin down with a computational model. Low-level visual similarity can be too specific to detect stylistically similar images, while manually crafted style categories can be too abstract to capture subtle style differences. We propose an unsupervised approach to learn a style-coherent representation. Our method leverages probabilistic polylingual topic models based on visual attributes to discover a set of latent style factors. Given a collection of unlabeled fash…
University of Trento（特伦托大学）；Tencent AI Lab（腾讯人工智能实验室）；Fondazione Bruno Kessler（布鲁诺·凯塞勒基金会）
Image-to-Image (I2I) multi-domain translation models are usually evaluated also using the quality of their semantic interpolation results. However, state-of-the-art models frequently show abrupt changes in the image appearance during interpolation, and usually perform poorly in interpolations across domains. In this paper, we propose a new training protocol based on three specific losses which help a translation network to learn a smooth and disentangled latent style space in which: 1) Both intra- and inter-domain interpolations correspond to gradual changes in the generated images and 2) The …
Deep learning has shown state-of-art classification performance on datasets such as ImageNet, which contain a single object in each image. However, multi-object classification is far more challenging. We present a unified framework which leverages the strengths of multiple machine learning methods, viz deep learning, probabilistic models and kernel methods to obtain state-of-art performance on Microsoft COCO, consisting of non-iconic images. We incorporate contextual information in natural images through a conditional latent tree probabilistic model (CLTM), where the object co-occurrences are …
Pengcheng Laboratory（鹏城实验室）；Shenzhen University（深圳大学）；University of Nottingham（诺丁汉大学）
Facial attributes in StyleGAN generated images are entangled in the latent space which makes it very difficult to independently control a specific attribute without affecting the others. Supervised attribute editing requires annotated training data which is difficult to obtain and limits the editable attributes to those with labels. Therefore, unsupervised attribute editing in an disentangled latent space is key to performing neat and versatile semantic face editing. In this paper, we present a new technique termed Structure-Texture Independent Architecture with Weight Decomposition and Orthog…
Seoul National University（首尔国立大学）；Yonsei University（延世大学）
Despite the success of diffusion models (DMs), we still lack a thorough understanding of their latent space. While image editing with GANs builds upon latent space, DMs rely on editing the conditions such as text prompts. We present an unsupervised method to discover interpretable editing directions for the latent variables $\mathbf{x}_t \in \mathcal{X}$ of DMs. Our method adopts Riemannian geometry between $\mathcal{X}$ and the intermediate feature maps $\mathcal{H}$ of the U-Nets to provide a deep understanding over the geometrical structure of $\mathcal{X}$. The discovered semantic latent d…
In this study, we focus on the unsupervised domain adaptation problem where an approximate inference model is to be learned from a labeled data domain and expected to generalize well to an unlabeled data domain. The success of unsupervised domain adaptation largely relies on the cross-domain feature alignment. Previous work has attempted to directly align latent features by the classifier-induced discrepancies. Nevertheless, a common feature space cannot always be learned via this direct feature alignment especially when a large domain gap exists. To solve this problem, we introduce a Gaussian…
Prediction and interpolation for long-range video data involves the complex task of modeling motion trajectories for each visible object, occlusions and dis-occlusions, as well as appearance changes due to viewpoint and lighting. Optical flow based techniques generalize but are suitable only for short temporal ranges. Many methods opt to project the video frames to a low dimensional latent space, achieving long-range predictions. However, these latent representations are often non-interpretable, and therefore difficult to manipulate. This work poses video prediction and interpolation as unsupe…
Unsupervised learning of feature representations is a challenging yet important problem for analyzing a large collection of multimedia data that do not have semantic labels. Recently proposed neural network-based unsupervised learning approaches have succeeded in obtaining features appropriate for classification of multimedia data. However, unsupervised learning of feature representations adapted to content-based matching, comparison, or retrieval of multimedia data has not been explored well. To obtain such retrieval-adapted features, we introduce the idea of combining diffusion distance on a…
We propose a novel unsupervised generative model that learns to disentangle object identity from other low-level aspects in class-imbalanced data. We first investigate the issues surrounding the assumptions about uniformity made by InfoGAN, and demonstrate its ineffectiveness to properly disentangle object identity in imbalanced data. Our key idea is to make the discovery of the discrete latent factor of variation invariant to identity-preserving transformations in real images, and use that as a signal to learn the appropriate latent distribution representing object identity. Experiments on bo…
King Abdullah University for Science and Technology (KAUST)（阿卜杜拉国王科技大学）
In multimodal unsupervised image-to-image translation tasks, the goal is to translate an image from the source domain to many images in the target domain. We present a simple method that produces higher quality images than current state-of-the-art while maintaining the same amount of multimodal diversity. Previous methods follow the unconditional approach of trying to map the latent code directly to a full-size image. This leads to complicated network architectures with several introduced hyperparameters to tune. By treating the latent code as a modifier of the convolutional filters, we produc…
University of Maryland, College Park（马里兰大学帕克分校）；Google Research（谷歌研究院）
Unsupervised representation learning holds the promise of exploiting large amounts of unlabeled data to learn general representations. A promising technique for unsupervised learning is the framework of Variational Auto-encoders (VAEs). However, unsupervised representations learned by VAEs are significantly outperformed by those learned by supervised learning for recognition. Our hypothesis is that to learn useful representations for recognition the model needs to be encouraged to learn about repeating and consistent patterns in data. Drawing inspiration from the mid-level representation disco…
Assigning consistent temporal identifiers to multiple moving objects in a video sequence is a challenging problem. A solution to that problem would have immediate ramifications in multiple object tracking and segmentation problems. We propose a strategy that treats the temporal identification task as a spatio-temporal clustering problem. We propose an unsupervised learning approach using a convolutional and fully connected autoencoder, which we call deep heterogeneous autoencoder, to learn discriminative features from segmentation masks and detection bounding boxes. We extract masks and their …
In this work we present Discrete Attend Infer Repeat (Discrete-AIR), a Recurrent Auto-Encoder with structured latent distributions containing discrete categorical distributions, continuous attribute distributions, and factorised spatial attention. While inspired by the original AIR model andretaining AIR model's capability in identifying objects in an image, Discrete-AIR provides direct interpretability of the latent codes. We show that for Multi-MNIST and a multiple-objects version of dSprites dataset, the Discrete-AIR model needs just one categorical latent variable, one attribute variable (…
Recent generative adversarial networks (GANs) are able to generate impressive photo-realistic images. However, controllable generation with GANs remains a challenging research problem. Achieving controllable generation requires semantically interpretable and disentangled factors of variation. It is challenging to achieve this goal using simple fixed distributions such as Gaussian distribution. Instead, we propose an unsupervised framework to learn a distribution of latent codes that control the generator through self-training. Self-training provides an iterative feedback in the GAN training, f…
To help agents reason about scenes in terms of their building blocks, we wish to extract the compositional structure of any given scene (in particular, the configuration and characteristics of objects comprising the scene). This problem is especially difficult when scene structure needs to be inferred while also estimating the agent's location/viewpoint, as the two variables jointly give rise to the agent's observations. We present an unsupervised variational approach to this problem. Leveraging the shared structure that exists across different scenes, our model learns to infer two sets of lat…
Unsupervised Domain Adaptation (UDA) refers to the problem of learning a model in a target domain where labeled data are not available by leveraging information from annotated data in a source domain. Most deep UDA approaches operate in a single-source, single-target scenario, i.e. they assume that the source and the target samples arise from a single distribution. However, in practice most datasets can be regarded as mixtures of multiple domains. In these cases, exploiting traditional single-source, single-target methods for learning classification models may lead to poor results. Furthermore…
Imperial College London（帝国理工学院）；Siemens Healthineers（西门子医疗）
We propose a fully unsupervised multi-modal deformable image registration method (UMDIR), which does not require any ground truth deformation fields or any aligned multi-modal image pairs during training. Multi-modal registration is a key problem in many medical image analysis applications. It is very challenging due to complicated and unknown relationships between different modalities. In this paper, we propose an unsupervised learning approach to reduce the multi-modal registration problem to a mono-modal one through image disentangling. In particular, we decompose images of both modalities …
TCS Research（塔塔咨询服务研究部）；Flytxt Mobile Solutions（Flytxt 移动解决方案公司）；Indian Institute of Space Science and Technology（印度空间科学技术研究所）
Several methods for discovering interpretable directions in the latent space of pre-trained GANs have been proposed. Latent semantics discovered by unsupervised methods are relatively less disentangled than supervised methods since they do not use pre-trained attribute classifiers. We propose Scale Ranking Estimator (SRE), which is trained using self-supervision. SRE enhances the disentanglement in directions obtained by existing unsupervised disentanglement techniques. These directions are updated to preserve the ordering of variation within each direction in latent space. Qualitative and qua…
Indian Institute of Technology Madras（印度理工学院马德拉斯分校）；Robert Bosch Center for Data Science and AI（罗伯特·博世数据科学与人工智能中心）
Deep convolutional neural networks (CNNs) for video denoising are typically trained with supervision, assuming the availability of clean videos. However, in many applications, such as microscopy, noiseless videos are not available. To address this, we propose an Unsupervised Deep Video Denoiser (UDVD), a CNN architecture designed to be trained exclusively with noisy data. The performance of UDVD is comparable to the supervised state-of-the-art, even when trained only on a single short noisy video. We demonstrate the promise of our approach in real-world imaging applications by denoising raw vi…
Existing Neural Architecture Search (NAS) methods either encode neural architectures using discrete encodings that do not scale well, or adopt supervised learning-based methods to jointly learn architecture representations and optimize architecture search on such representations which incurs search bias. Despite the widespread use, architecture representations learned in NAS are still poorly understood. We observe that the structural properties of neural architectures are hard to preserve in the latent space if architecture representation learning and search are coupled, resulting in less effe…
We show that unsupervised training of latent capsule layers using only the reconstruction loss, without masking to select the correct output class, causes a loss of equivariances and other desirable capsule qualities. This implies that supervised capsules networks can't be very deep. Unsupervised sparsening of latent capsule layer activity both restores these qualities and appears to generalize better than supervised masking, while potentially enabling deeper capsules networks. We train a sparse, unsupervised capsules network of similar geometry to Sabour et al (2017) on MNIST, and then test c…
Tsinghua University（清华大学）；Institute for AI（人工智能研究院）；BNRist Center（北京信息科学与技术国家研究中心）；Tsinghua-Bosch Joint ML Center（清华-博世机器学习联合研究中心）；THBI Lab（清华脑与智能实验室）
We present Mixture of Contrastive Experts (MiCE), a unified probabilistic clustering framework that simultaneously exploits the discriminative representations learned by contrastive learning and the semantic structures captured by a latent mixture model. Motivated by the mixture of experts, MiCE employs a gating function to partition an unlabeled dataset into subsets according to the latent semantics and multiple experts to discriminate distinct subsets of instances assigned to them in a contrastive learning manner. To solve the nontrivial inference and learning problems caused by the latent v…
LightenDiffusion: Unsupervised Low-Light Image Enhancement with Latent-Retinex Diffusion Models
Shanghai Jiao Tong University（上海交通大学）；Megvii Technology（旷视科技）；Sichuan University（四川大学）；Southwest Jiaotong University（西南交通大学）；University of Electronic Science and Technology of China（电子科技大学）
