Collecting labeled data for the task of semantic segmentation is expensive and time-consuming, as it requires dense pixel-level annotations. While recent Convolutional Neural Network (CNN) based semantic segmentation approaches have achieved impressive results by using large amounts of labeled training data, their performance drops significantly as the amount of labeled data decreases. This happens because deep CNNs trained with the de facto cross-entropy loss can easily overfit to small amounts of labeled data. To address this issue, we propose a simple and effective contrastive learning-based training strategy in which we first pretrain the network using a pixel-wise, label-based contrastive loss, and then fine-tune it using the cross-entropy loss. This approach increases intra-class compactness and inter-class separability, thereby resulting in a better pixel classifier. We demonstrate the effectiveness of the proposed training strategy using the Cityscapes and PASCAL VOC 2012 segmentation datasets. Our results show that pretraining with the proposed contrastive loss results in large performance gains (more than 20% absolute improvement in some settings) when the amount of labeled data is limited. In many settings, the proposed contrastive pretraining strategy, which does not use any additional data, is able to match or outperform the widely-used ImageNet pretraining strategy that uses more than a million additional labeled images.
Many recent approaches in contrastive learning have worked to close the gap between pretraining on iconic images like ImageNet and pretraining on complex scenes like COCO. This gap exists largely because commonly used random crop augmentations obtain semantically inconsistent content in crowded scene images of diverse objects. Previous works use preprocessing pipelines to localize salient objects for improved cropping, but an end-to-end solution is still elusive. In this work, we propose a framework which accomplishes this goal via joint learning of representations and segmentation. We leverag…
Carleton University（卡尔顿大学）；Canada CIFAR AI Chair（加拿大CIFAR人工智能讲席）
Medical image segmentation methods typically rely on numerous dense annotated images for model training, which are notoriously expensive and time-consuming to collect. To alleviate this burden, weakly supervised techniques have been exploited to train segmentation models with less expensive annotations. In this paper, we propose a novel point-supervised contrastive variance method (PSCV) for medical image semantic segmentation, which only requires one pixel-point from each organ category to be annotated. The proposed method trains the base segmentation network by using a novel contrastive vari…
Medical image segmentation, or computing voxelwise semantic masks, is a fundamental yet challenging task to compute a voxel-level semantic mask. To increase the ability of encoder-decoder neural networks to perform this task across large clinical cohorts, contrastive learning provides an opportunity to stabilize model initialization and enhance encoders without labels. However, multiple target objects (with different semantic meanings) may exist in a single image, which poses a problem for adapting traditional contrastive learning methods from prevalent 'image-level classification' to 'pixel-l…
Queen Mary University of London（伦敦玛丽女王大学）；Communication University of Zhejiang（浙江传媒学院）；University of Leicester（莱斯特大学）；Hangzhou Dianzi University（杭州电子科技大学）
In this paper, we introduce an unsupervised cancer segmentation framework for histology images. The framework involves an effective contrastive learning scheme for extracting distinctive visual representations for segmentation. The encoder is a Deep U-Net (DU-Net) structure that contains an extra fully convolution layer compared to the normal U-Net. A contrastive learning scheme is developed to solve the problem of lacking training sets with high-quality annotations on tumour boundaries. A specific set of data augmentation techniques are employed to improve the discriminability of the learned …
Parotid gland tumor is a common type of head and neck tumor. Segmentation of the parotid glands and tumors by MR images is important for the treatment of parotid gland tumors. However, segmentation of the parotid glands is particularly challenging due to their variable shape and low contrast with surrounding structures. Recently deep learning has developed rapidly, which can handle complex problems. However, most of the current deep learning methods for processing medical images are still based on supervised learning. Compared with natural images, medical images are difficult to acquire and co…
Recent advances in self-supervised contrastive learning yield good image-level representation, which favors classification tasks but usually neglects pixel-level detailed information, leading to unsatisfactory transfer performance to dense prediction tasks such as semantic segmentation. In this work, we propose a pixel-wise contrastive learning method called CP2 (Copy-Paste Contrastive Pretraining), which facilitates both image- and pixel-level representation learning and therefore is more suitable for downstream dense prediction tasks. In detail, we copy-paste a random crop from an image (the…
Current contrastive learning frameworks focus on leveraging a single supervisory signal to learn representations, which limits the efficacy on unseen data and downstream tasks. In this paper, we present a hierarchical multi-label representation learning framework that can leverage all available labels and preserve the hierarchical relationship between classes. We introduce novel hierarchy preserving losses, which jointly apply a hierarchical penalty to the contrastive loss, and enforce the hierarchy constraint. The loss function is data driven and automatically adapts to arbitrary multi-label …
We present a self-supervised learning (SSL) method suitable for semi-global tasks such as object detection and semantic segmentation. We enforce local consistency between self-learned features, representing corresponding image locations of transformed versions of the same image, by minimizing a pixel-level local contrastive (LC) loss during training. LC-loss can be added to existing self-supervised learning methods with minimal overhead. We evaluate our SSL approach on two downstream tasks -- object detection and semantic segmentation, using COCO, PASCAL VOC, and CityScapes datasets. Our metho…
Improving Multi-Label Contrastive Learning by Leveraging Label Distribution
College of Computer Science and Software Engineering, Hohai University（河海大学计算机与软件学院）；State Key Laboratory for Novel Software Technology, Nanjing University（南京大学计算机软件新技术国家重点实验室）
A large amount of manual segmentation is typically required to train a robust segmentation network so that it can segment objects of interest in a new imaging modality. The manual efforts can be alleviated if the manual segmentation in one imaging modality (e.g., CT) can be utilized to train a segmentation network in another imaging modality (e.g., CBCT/MRI/PET). In this work, we developed an anatomy-constrained contrastive synthetic segmentation network (AccSeg-Net) to train a segmentation network for a target imaging modality without using its ground truth. Specifically, we proposed to use a…
Samsung SDS Research America（三星SDS美国研究院）；UC Berkeley（加州大学伯克利分校）
3D deep learning is a growing field of interest due to the vast amount of information stored in 3D formats. Triangular meshes are an efficient representation for irregular, non-uniform 3D objects. However, meshes are often challenging to annotate due to their high geometrical complexity. Specifically, creating segmentation masks for meshes is tedious and time-consuming. Therefore, it is desirable to train segmentation networks with limited-labeled data. Self-supervised learning (SSL), a form of unsupervised representation learning, is a growing alternative to fully-supervised learning which ca…
Tsinghua University（清华大学）；Tencent Youtu Lab（腾讯优图实验室）；University College London（伦敦大学学院）
Few-shot semantic segmentation aims to segment novel-class objects in a query image with only a few annotated examples in support images. Most of advanced solutions exploit a metric learning framework that performs segmentation through matching each pixel to a learned foreground prototype. However, this framework suffers from biased classification due to incomplete construction of sample pairs with the foreground prototype only. To address this issue, in this paper, we introduce a complementary self-contrastive task into few-shot semantic segmentation. Our new model is able to associate the pi…
Nanyang Technological University（南洋理工大学）；National University of Singapore（新加坡国立大学）
With large-scale well-labeled datasets, deep learning has shown significant success in medical image segmentation. However, it is challenging to acquire abundant annotations in clinical practice due to extensive expertise requirements and costly labeling efforts. Recently, contrastive learning has shown a strong capacity for visual representation learning on unlabeled data, achieving impressive performance rivaling supervised learning in many domains. In this work, we propose a novel multi-scale multi-view global-local contrastive learning (MMGL) framework to thoroughly explore global and loca…
Jilin University（吉林大学）；Baidu Research（百度研究院）；National Engineering Laboratory for Deep Learning Technology and Application（深度学习技术及应用国家工程实验室）
Current semi-supervised semantic segmentation methods mainly focus on designing pixel-level consistency and contrastive regularization. However, pixel-level regularization is sensitive to noise from pixels with incorrect predictions, and pixel-level contrastive regularization has memory and computational cost with O(pixel_num^2). To address the issues, we propose a novel region-level contrastive and consistency learning framework (RC^2L) for semi-supervised semantic segmentation. Specifically, we first propose a Region Mask Contrastive (RMC) loss and a Region Feature Contrastive (RFC) loss to …
We study Online Continual Learning with missing labels and propose SemiCon, a new contrastive loss designed for partly labeled data. We demonstrate its efficiency by devising a memory-based method trained on an unlabeled data stream, where every data added to memory is labeled using an oracle. Our approach outperforms existing semi-supervised methods when few labels are available, and obtain similar results to state-of-the-art supervised methods while using only 2.6% of labels on Split-CIFAR10 and 10% of labels on Split-CIFAR100.
Computer Vision Laboratory, ETH Zurich（苏黎世联邦理工学院计算机视觉实验室）
Supervised deep learning-based methods yield accurate results for medical image segmentation. However, they require large labeled datasets for this, and obtaining them is a laborious task that requires clinical expertise. Semi/self-supervised learning-based approaches address this limitation by exploiting unlabeled data along with limited annotated data. Recent self-supervised learning methods use contrastive loss to learn good global level representations from unlabeled images and achieve high performance in classification tasks on popular natural image datasets like ImageNet. In pixel-level …
Mohamed bin Zayed University of Artificial Intelligence（穆罕默德·本·扎耶德人工智能大学）
Contrastive learning has proven useful in many applications where access to labelled data is limited. The lack of annotated data is particularly problematic in medical image segmentation as it is difficult to have clinical experts manually annotate large volumes of data such as cardiac structures in ultrasound images of the heart. In this paper, We propose a self supervised contrastive learning method to segment the left ventricle from echocardiography when limited annotated images exist. Furthermore, we study the effect of contrastive pretraining on two well-known segmentation networks, UNet …
Contrastive learning has shown great promise over annotation scarcity problems in the context of medical image segmentation. Existing approaches typically assume a balanced class distribution for both labeled and unlabeled medical images. However, medical image data in reality is commonly imbalanced (i.e., multi-class label imbalance), which naturally yields blurry contours and usually incorrectly labels rare objects. Moreover, it remains unclear whether all negative samples are equally negative. In this work, we present ACTION, an Anatomical-aware ConTrastive dIstillatiON framework, for semi-…
TreeGaussian: Tree-Guided Cascaded Contrastive Learning for Hierarchical Consistent 3D Gaussian Scene Segmentation and Understanding
Institute of Computing Technology, Chinese Academy of Sciences（中国科学院计算技术研究所）；University of Chinese Academy of Sciences（中国科学院大学）；Beihang University（北京航空航天大学）
To overcome the data-hungry challenge, we have proposed a semi-supervised contrastive learning framework for the task of class-imbalanced semantic segmentation. First and foremost, to make the model operate in a semi-supervised manner, we proposed the confidence-level-based contrastive learning to achieve instance discrimination in an explicit manner, and make the low-confidence low-quality features align with the high-confidence counterparts. Moreover, to tackle the problem of class imbalance in crack segmentation and road components extraction, we proposed the data imbalance loss to replace …
University of Illinois at Urbana-Champaign（伊利诺伊大学厄巴纳-香槟分校）；X The Moonshot Factory（X 登月工厂）
We present a novel semi-supervised semantic segmentation method which jointly achieves two desiderata of segmentation model regularities: the label-space consistency property between image augmentations and the feature-space contrastive property among different pixels. We leverage the pixel-level L2 loss and the pixel contrastive loss for the two purposes respectively. To address the computational efficiency issue and the false negative noise issue involved in the pixel contrastive loss, we further introduce and investigate several negative sampling techniques. Extensive experiments demonstrat…
GS-EMA: Integrating Gradient Surgery Exponential Moving Average with Boundary-Aware Contrastive Learning for Enhanced Domain Generalization in Aneurysm Segmentation
University of Leeds（利兹大学）；University of Manchester（曼彻斯特大学）
Deep networks trained on the source domain show degraded performance when tested on unseen target domain data. To enhance the model's generalization ability, most existing domain generalization methods learn domain invariant features by suppressing domain sensitive features. Different from them, we propose a Domain Projection and Contrastive Learning (DPCL) approach for generalized semantic segmentation, which includes two modules: Self-supervised Source Domain Projection (SSDP) and Multi-level Contrastive Learning (MLCL). SSDP aims to reduce domain gap by projecting data to the source domain,…
We propose a framework using contrastive learning as a pre-training task to perform image classification in the presence of noisy labels. Recent strategies such as pseudo-labeling, sample selection with Gaussian Mixture models, weighted supervised contrastive learning have been combined into a fine-tuning phase following the pre-training. This paper provides an extensive empirical study showing that a preliminary contrastive learning step brings a significant gain in performance when using different loss functions: non-robust, robust, and early-learning regularized. Our experiments performed o…
Stony Brook University（石溪大学）；University of Washington（华盛顿大学）；Tencent AI Lab（腾讯人工智能实验室）
Labels are costly and sometimes unreliable. Noisy label learning, semi-supervised learning, and contrastive learning are three different strategies for designing learning processes requiring less annotation cost. Semi-supervised learning and contrastive learning have been recently demonstrated to improve learning strategies that address datasets with noisy labels. Still, the inner connections between these fields as well as the potential to combine their strengths together have only started to emerge. In this paper, we explore further ways and advantages to fuse them. Specifically, we propose …
We introduce Patch Aligned Contrastive Learning (PACL), a modified compatibility function for CLIP's contrastive loss, intending to train an alignment between the patch tokens of the vision encoder and the CLS token of the text encoder. With such an alignment, a model can identify regions of an image corresponding to a given text input, and therefore transfer seamlessly to the task of open vocabulary semantic segmentation without requiring any segmentation annotations during training. Using pre-trained CLIP encoders with PACL, we are able to set the state-of-the-art on the task of open vocabul…
Prototype Contrastive Consistency Learning for Semi-Supervised Medical Image Segmentation
Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences（中国科学院深圳先进技术研究院）；Computer Vision Institute, College of Computer Science and Software Engineering, Shenzhen University（深圳大学计算机与软件学院计算机视觉研究所）；Baoan Central Hospital of Shenzhen（深圳市宝安中心医院）
Universidad de Zaragoza（萨拉戈萨大学）；Magic Leap（Magic Leap公司）；Bitbrain（Bitbrain公司）
This work presents a novel approach for semi-supervised semantic segmentation. The key element of this approach is our contrastive learning module that enforces the segmentation network to yield similar pixel-level feature representations for same-class samples across the whole dataset. To achieve this, we maintain a memory bank continuously updated with relevant and high-quality feature vectors from labeled data. In an end-to-end training, the features from both labeled and unlabeled data are optimized to be similar to same-class samples from the memory bank. Our approach outperforms the curr…
F Hoffmann-La Roche AG（罗氏公司）；Genentech Inc（基因泰克公司）；ETH Zurich（苏黎世联邦理工学院）；Uppsala University（乌普萨拉大学）
Accurate segmentation of retinal fluids in 3D Optical Coherence Tomography images is key for diagnosis and personalized treatment of eye diseases. While deep learning has been successful at this task, trained supervised models often fail for images that do not resemble labeled examples, e.g. for images acquired using different devices. We hereby propose a novel semi-supervised learning framework for segmentation of volumetric images from new unlabeled domains. We jointly use supervised and contrastive learning, also introducing a contrastive pairing scheme that leverages similarity between nea…
Automatic segmentation of brain MR images into white matter (WM), gray matter (GM), and cerebrospinal fluid (CSF) is critical for tissue volumetric analysis and cortical surface reconstruction. Due to dramatic structural and appearance changes associated with developmental and aging processes, existing brain tissue segmentation methods are only viable for specific age groups. Consequently, methods developed for one age group may fail for another. In this paper, we make the first attempt to segment brain tissues across the entire human lifespan (0-100 years of age) using a unified deep learning…
SuperCL: Superpixel Guided Contrastive Learning for Medical Image Segmentation Pre-training
Institute of Medical Technology, Peking University Health Science Center, Peking University（北京大学医学部医学技术研究所）；Department of Biomedical Engineering, Peking University（北京大学生物医学工程系）；National Biomedical Imaging Center, Peking University（北京大学国家生物医学成像中心）；Institute of Biomedical Engineering, Shenzhen Bay Laboratory（深圳湾实验室生物医学工程研究所）；Institute of Biomedical Engineering, Peking University Shenzhen Graduate School（北京大学深圳研究生院生物医学工程研究所）
For an image query, unsupervised contrastive learning labels crops of the same image as positives, and other image crops as negatives. Although intuitive, such a native label assignment strategy cannot reveal the underlying semantic similarity between a query and its positives and negatives, and impairs performance, since some negatives are semantically similar to the query or even share the same semantic class as the query. In this work, we first prove that for contrastive learning, inaccurate label assignment heavily impairs its generalization for semantic instance discrimination, while accu…
Multi-level Asymmetric Contrastive Learning for Volumetric Medical Image Segmentation Pre-training
Peking University（北京大学）；Peking University Health Science Center（北京大学医学部）；National Biomedical Imaging Center（国家生物医学成像中心）；Peking University Shenzhen Graduate School（北京大学深圳研究生院）；Georgia Institute of Technology（佐治亚理工学院）；UT Southwestern Medical Center（西南大学达拉斯医学中心）
PRCL: Probabilistic Representation Contrastive Learning for Semi-Supervised Semantic Segmentation
School of Computer Science and Engineering, Northeastern University（东北大学计算机科学与工程学院）；Intelligent Game and Decision Laboratory（智能游戏与决策实验室）；Alibaba DAMO Academy, Alibaba Group（阿里巴巴集团达摩院）；Zhejiang University（浙江大学）
We introduce a novel approach to unsupervised and semi-supervised domain adaptation for semantic segmentation. Unlike many earlier methods that rely on adversarial learning for feature alignment, we leverage contrastive learning to bridge the domain gap by aligning the features of structurally similar label patches across domains. As a result, the networks are easier to train and deliver better performance. Our approach consistently outperforms state-of-the-art unsupervised and semi-supervised methods on two challenging domain adaptive segmentation tasks, particularly with a small number of ta…
Loughborough University（拉夫堡大学）；Cardiff University（卡迪夫大学）；Central South University（中南大学）
Weakly supervised semantic segmentation (WSSS) has gained significant popularity since it relies only on weak labels such as image level annotations rather than pixel level annotations required by supervised semantic segmentation (SSS) methods. Despite drastically reduced annotation costs, typical feature representations learned from WSSS are only representative of some salient parts of objects and less reliable compared to SSS due to the weak guidance during training. In this paper, we propose a novel Multi-Strategy Contrastive Learning (MuSCLe) framework to obtain enhanced feature representa…
Medical image segmentation has been widely recognized as a pivot procedure for clinical diagnosis, analysis, and treatment planning. However, the laborious and expensive annotation process lags down the speed of further advances. Contrastive learning-based weight pre-training provides an alternative by leveraging unlabeled data to learn a good representation. In this paper, we investigate how contrastive learning benefits the general supervised medical segmentation tasks. To this end, patch-dragsaw contrastive regularization (PDCR) is proposed to perform patch-level tugging and repulsing with …
Nanyang Technological University（南洋理工大学）；National University of Singapore（新加坡国立大学）
Domain shift has been a long-standing issue for medical image segmentation. Recently, unsupervised domain adaptation (UDA) methods have achieved promising cross-modality segmentation performance by distilling knowledge from a label-rich source domain to a target domain without labels. In this work, we propose a multi-scale self-ensembling based UDA framework for automatic segmentation of two key brain structures i.e., Vestibular Schwannoma (VS) and Cochlea on high-resolution T2 images. First, a segmentation-enhanced contrastive unpaired image translation module is designed for image-level doma…
Fully supervised semantic segmentation learns from dense masks, which requires heavy annotation cost for closed set. In this paper, we use natural language as supervision without any pixel-level annotation for open world segmentation. We call the proposed framework as FreeSeg, where the mask is freely available from raw feature map of pretraining model. Compared with zero-shot or openset segmentation, FreeSeg doesn't require any annotated masks, and it widely predicts categories beyond class-agnostic unsupervised segmentation. Specifically, FreeSeg obtains free mask from Image-Text Similarity …
Medical image segmentation is a relevant task as it serves as the first step for several diagnosis processes, thus it is indispensable in clinical usage. Whilst major success has been reported using supervised techniques, they assume a large and well-representative labelled set. This is a strong assumption in the medical domain where annotations are expensive, time-consuming, and inherent to human bias. To address this problem, unsupervised techniques have been proposed in the literature yet it is still an open problem due to the difficulty of learning any transformation pattern. In this work,…
University College London（伦敦大学学院）；King’s College London（伦敦国王学院）；Moorfields Eye Hospital（摩尔菲尔兹眼科医院）
This work considers supervised contrastive learning for semantic segmentation. We apply contrastive learning to enhance the discriminative power of the multi-scale features extracted by semantic segmentation networks. Our key methodological insight is to leverage samples from the feature spaces emanating from multiple stages of a model's encoder itself requiring neither data augmentation nor online memory banks to obtain a diverse set of samples. To allow for such an extension we introduce an efficient and effective sampling process, that enables applying contrastive losses over the encoder's …
Existed pre-trained models have achieved state-of-the-art performance on various text classification tasks. These models have proven to be useful in learning universal language representations. However, the semantic discrepancy between similar texts cannot be effectively distinguished by advanced pre-trained models, which have a great influence on the performance of hard-to-distinguish classes. To address this problem, we propose a novel Contrastive Learning with Label Distance (CLLD) in this work. Inspired by recent advances in contrastive learning, we specifically design a classification met…
Institute of Information Science, Beijing Jiaotong University（北京交通大学信息科学研究所）；Beijing Key Laboratory of Advanced Information Science and Network Technology, Beijing Jiaotong University（北京交通大学先进信息科学与网络技术北京市重点实验室）；Department of Computer Science and Engineering, Michigan State University（密歇根州立大学计算机科学与工程系）
To bridge the gap between the source and target domains in unsupervised domain adaptation (UDA), the most common strategy puts focus on matching the marginal distributions in the feature space through adversarial learning. However, such category-agnostic global alignment lacks of exploiting the class-level joint distributions, causing the aligned distribution less discriminative. To address this issue, we propose in this paper a novel margin preserving self-paced contrastive Learning (MPSCL) model for cross-modal medical image segmentation. Unlike the conventional construction of contrastive p…
