基于光敏偶氮苯薄膜生物基质的光可调谐光学细胞操纵
Light-tunable optical cell manipulation via photoactive azobenzene-containing thin film bio-substrate
摘要：
在体内，实时研究的局部和集体的细胞生物力学响应需要精细和选择性的细胞环境的操纵。一种创新的途径是使用光活性生物基质，如含偶氮苯的材料，其表现出壮观的光机械性能，以光学触发细胞的局部机械刺激。兴奋的细胞表现出壮观的形态变化和面积缩小，这是依赖于照明。这证明了光机械活性基底研究细胞与其环境的机械相互作用所产生的现象的能力。
英文摘要：
In-vivo, real-time study of the local and collective cellular biomechanical responses requires the fine and selective manipulation of the cellular environment. One innovative pathway is the use of photoactive bio-substrates such as azobenzene-containing materials, which exhibit spectacular photomechanical properties, to optically trigger the local, mechanical stimulation of cells. Excited cells exhibit spectacular morphological modifications and area shrinkage, which are dependent on the illumination. This demonstrates the capabilities of photomechanically active substrates to study the phenomena resulting from the mechanical interaction of cells with their environment.
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