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arXiv 2011.10505cs.LGcond-mat.mtrl-scics.CVeess.IVphysics.app-ph
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合成图像渲染解决了深度学习纳米颗粒分割中的注释问题

Synthetic Image Rendering Solves Annotation Problem in Deep Learning Nanoparticle Segmentation

Friedrich-Alexander-University Erlangen-Nuremberg(弗里德里希-亚历山大大学埃尔朗根-纽伦堡分校);Institut für Nanotechnologie und korrelative Mikroskopie(纳米技术与相关显微学研究所);Flemish Institute for Technological Research(佛兰德技术研究所);Luxembourg Institute of Science and Technology(卢森堡科学技术研究所);Fraunhofer Institute for Ceramic Technologies and Systems(弗劳恩霍夫陶瓷技术与系统研究所)
Leonid Mill, David Wolff, Nele Gerrits, Patrick Philipp, Lasse Kling, Florian Vollnhals, Andrew Ignatenko, Christian Jaremenko, Yixing Huang, Olivier De Castro,… 展开作者

Leonid Mill, David Wolff, Nele Gerrits, Patrick Philipp, Lasse Kling, Florian Vollnhals, Andrew Ignatenko, Christian Jaremenko, Yixing Huang, Olivier De Castro, Jean-Nicolas Audinot, Inge Nelissen, Tom Wirtz, Andreas Maier, Silke Christiansen

摘要:

纳米颗粒作为人为过程的结果出现在各种环境中,这引起了人们对它们对环境和人类健康影响的担忧。为了进行适当的风险评估,需要对颗粒特性(例如尺寸、形状和成分)进行精确和统计相关的分析,这将极大地受益于自动图像分析程序。虽然深度学习在目标检测任务中显示出令人印象深刻的结果,但其适用性受到代表性的、实验收集的和手动注释的训练数据的数量的限制。在这里,我们提出了一个优雅,灵活和通用的方法,绕过这个昂贵和繁琐的数据采集过程。我们表明,使用渲染软件可以生成逼真的合成训练数据,以训练最先进的深度神经网络。使用这种方法,我们得到一个分割的准确性,是可比的毒理学相关的金属氧化物纳米粒子合奏,我们选择作为例子的人为注释。我们的研究为使用深度学习在各种成像技术(如显微镜和光谱)中进行自动化,高通量颗粒检测铺平了道路,用于各种研究和应用,包括塑料微米和纳米颗粒的检测。

英文摘要:

Nanoparticles occur in various environments as a consequence of man-made processes, which raises concerns about their impact on the environment and human health. To allow for proper risk assessment, a precise and statistically relevant analysis of particle characteristics (such as e.g. size, shape and composition) is required that would greatly benefit from automated image analysis procedures. While deep learning shows impressive results in object detection tasks, its applicability is limited by the amount of representative, experimentally collected and manually annotated training data. Here, we present an elegant, flexible and versatile method to bypass this costly and tedious data acquisition process. We show that using a rendering software allows to generate realistic, synthetic training data to train a state-of-the art deep neural network. Using this approach, we derive a segmentation accuracy that is comparable to man-made annotations for toxicologically relevant metal-oxide nanoparticle ensembles which we chose as examples. Our study paves the way towards the use of deep learning for automated, high-throughput particle detection in a variety of imaging techniques such as microscopies and spectroscopies, for a wide variety of studies and applications, including the detection of plastic micro- and nanoparticles.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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