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arXiv 2011.06879stat.COstat.ME
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NLMEModeling:用于动力系统非线性混合效应建模的Wolfram Mathematica软件包

NLMEModeling: A Wolfram Mathematica Package for Nonlinear Mixed Effects Modeling of Dynamical Systems

Jacob Leander, Joachim Almquist, Anna Johnning, Julia Larsson, Mats Jirstrand

摘要:

非线性混合效应建模是分析实验中多个实体的数据时的强大工具。在本文中,我们介绍了NLMEModeling,一个Wolfram Mathematica中的混合效果建模软件包。NLMEModeling支持动态系统的混合效应建模,其中底层动态由普通或随机微分方程与灵活的观测误差模型相结合来描述。此外,NLMEModeling是一个用户友好的软件包,具有模型验证,可视化预测检查和模拟功能。该软件包免费提供,并为Wolfram Mathematica提供了一个灵活的附加组件。

英文摘要:

Nonlinear mixed effects modeling is a powerful tool when analyzing data from several entities in an experiment. In this paper, we present NLMEModeling, a package for mixed effects modeling in Wolfram Mathematica. NLMEModeling supports mixed effects modeling of dynamical systems where the underlying dynamics are described by either ordinary or stochastic differential equations combined with a flexible observation error model. Moreover, NLMEModeling is a user-friendly package with functionality for model validation, visual predictive checks and simulation capabilities. The package is freely available and provides a flexible add-on to Wolfram Mathematica.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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