无模板法制备生物相容性温敏磁纤毛
Template-Free Preparation of Thermoresponsive Mag-netic Cilia Compatible with Biological Conditions
摘要：
仿生材料通常用于功能性设备的开发。模拟生物功能的人工纤毛的制造已经成为一个有前途的策略，在小型化系统中的流体操纵。在这项研究中，我们提出了一个不同的物理化学见解的基础上的温度触发可逆组装的涂层氧化铁纳米粒子的生物相容性无模板的方法制备磁性纤毛。所制备的纤毛的长度可以在10和100微米之间调节，在具有约8微米的持久长度的非常密集的柔性结构阵列中达到高达100的纵横比。纤毛的磁致动显示了强大的结构（超过几个小时的驱动），具有广泛的弯曲幅度，从高敏感性的细丝。结果表明，所提出的策略是一种有效的和通用的替代模板的制造方法和生产纤毛具有显着的特点和尺寸内的无模板的方法。
英文摘要：
Bio-inspired materials are commonly used in the development of functional devices. The fabrication of artificial cilia mimicking the biological functions has emerged as a promising strategy for fluid manipulation in miniaturized systems. In this study, we propose a different physicochemical insight for the preparation of magnetic cilia based on the temperature-triggered reversible assembly of coated iron oxide nanoparticles in a bio-compatible template-free approach. The length of the prepared cilia could be tuned between 10 and 100 microns reaching aspect ratios up to 100 in a very dense array of flexible structures with persistence lengths around 8 microns. Magnetic actuation of the cilia revealed robust structures (over several hours of actuation) with a wide range of bending amplitudes resulting from high susceptibility of the filaments. The results demonstrate that the proposed strategy is an efficient and versatile alternative for templated fabrication methods and producing cilia with remarkable characteristics and dimensions within the template-free approaches.
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