多点应用的HYPERSCINT闪烁剂量学研究平台的比较光学和剂量学特性
Comparative optic and dosimetric characterization of the HYPERSCINT scintillation dosimetry research platform for multipoint applications
摘要：
这项研究介绍了HYPERSCINT研究平台，第一个商业化的闪烁剂量测量平台，能够通过高光谱方法进行多点剂量测量。通过与另一种市售解决方案海洋光学QE65Pro光谱仪的比较，研究了该系统的光学和剂量学性能。通过测量信号的线性度作为两个系统的积分时间、光子检测效率和光谱分辨率的函数来完成光学表征。然后使用3点塑料闪烁体检测器（mPSD）根据与每个闪烁体相关的信噪比（SNR）和信号背景比（SBR）评价剂量测定性能。随后将后者与文献中发现的Exradin W1（一种单点塑料闪烁体探测器）进行了比较。最后，使用HYPERSCINT平台实现了各种射束测量，以评估其执行临床光子束剂量测定的能力。发现两种系统在作为强度的函数的信号的线性方面是相当的。虽然QE65Pro拥有更高的光谱分辨率，但HYPERSCINT的检测效率高达1000倍。剂量测量表明，后者还提供了更好的SNR和SBR，甚至超过了Exradin W1单点PSD的SNR。虽然使用与mPSD耦合的HYPERSCINT平台准确测量了1 cGy至600 cGy的剂量，但在预测剂量的2.1%范围内，海洋光学光谱仪在50 cGy下显示出高达86%的差异。同样，使用HYPERSCINT平台，深度剂量、射束轮廓半峰全宽和输出因子均在预测剂量的2.3%范围内准确测量，平均差异分别为0.5%、1.6%和0.6%。
英文摘要：
This study introduces the HYPERSCINT research platform, the first commercially available scintillation dosimetry platform capable of multi-point dosimetry through the hyperspectral approach. Optic and dosimetric performances of the system were investigated through comparison with another commercially available solution, the Ocean Optics QE65Pro spectrometer. The optical characterization was accomplished by measuring the linearity of the signal as a function of integration time, photon detection efficiency and spectral resolution for both systems. Dosimetric performances were then evaluated with a 3-point plastic scintillator detector (mPSD) in terms of signal to noise ratio (SNR) and signal to background ratio (SBR) associated with each scintillator. The latter were subsequently compared with those found in the literature for the Exradin W1, a single-point plastic scintillator detector. Finally, various beam measurements were realized with the HYPERSCINT platform to evaluate its ability to perform clinical photon beam dosimetry. Both systems were found to be comparable in terms of linearity of the signal as a function of the intensity. Although the QE65Pro possesses a higher spectral resolution, the detection efficency of the HYPERSCINT is up to 1000 time greater. Dosimetric measurements shows that the latter also offers a better SNR and SBR, surpassing even the SNR of the Exradin W1 single-point PSD. While the doses ranging from 1 cGy to 600 cGy were accurately measured within 2.1% of the predicted dose using the HYPERSCINT platform coupled to the mPSD, the Ocean optics spectrometer shows discrepencies up to 86% under 50cGy. Similarly, depth dose, full width at half maximum region of the beam profile and output factors were all accurately measured within 2.3% of the predicted dose using the HYPERSCINT platform and exhibit an average difference of 0.5%, 1.6% and 0.6%, respectively.
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