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arXiv 2009.02797cs.CV
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用于缺失婴儿皮质表面纵向预测的生长轨迹的深度建模

Deep Modeling of Growth Trajectories for Longitudinal Prediction of Missing Infant Cortical Surfaces

University of North Carolina at Chapel Hill(北卡罗来纳大学教堂山分校)

Peirong Liu, Zhengwang Wu, Gang Li, Pew-Thian Yap, Dinggang Shen

摘要:

绘制皮层生长轨迹对于理解大脑发育至关重要。然而,这种分析需要收集纵向数据,由于受试者脱落和扫描失败,这可能具有挑战性。在本文中,我们将介绍一种使用空间图卷积神经网络(GCNN)进行皮质表面纵向预测的方法,该方法将传统的CNN从欧几里得扩展到弯曲流形。所提出的方法被设计用于对皮质生长轨迹进行建模,并在多个时间点联合预测皮质内表面和外表面。在损失计算中采用二进制标记来处理缺失数据,我们充分利用所有可用的皮层表面来训练我们的深度学习模型,而不需要完整的纵向数据收集。预测表面直接允许皮质属性,如皮质厚度,曲率和凸度计算用于后续分析。我们将证明与实验结果表明,我们的方法是能够捕捉时空皮层生长模式的非线性,并可以预测皮质表面的精度提高。

英文摘要:

Charting cortical growth trajectories is of paramount importance for understanding brain development. However, such analysis necessitates the collection of longitudinal data, which can be challenging due to subject dropouts and failed scans. In this paper, we will introduce a method for longitudinal prediction of cortical surfaces using a spatial graph convolutional neural network (GCNN), which extends conventional CNNs from Euclidean to curved manifolds. The proposed method is designed to model the cortical growth trajectories and jointly predict inner and outer cortical surfaces at multiple time points. Adopting a binary flag in loss calculation to deal with missing data, we fully utilize all available cortical surfaces for training our deep learning model, without requiring a complete collection of longitudinal data. Predicting the surfaces directly allows cortical attributes such as cortical thickness, curvature, and convexity to be computed for subsequent analysis. We will demonstrate with experimental results that our method is capable of capturing the nonlinearity of spatiotemporal cortical growth patterns and can predict cortical surfaces with improved accuracy.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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