全脑模型探索自下而上的意识状态改变
Whole-brain models to explore altered states of consciousness from the bottom up
摘要：
人类意识的范围包括脱离我们大多数人所经历的普通觉醒的状态。这些意识状态的改变为研究大脑活动的整体变化如何与不同的主观体验联系起来提供了一个绝佳的机会。我们考虑的问题，解释如何全球签名的改变意识产生的大规模连接和本地的动力学规则，可以追溯到已知的神经组织的属性之间的相互作用。为此，我们提倡一项研究计划，旨在弥合自下而上的全脑活动生成模型与意识理论提出的自上而下的签名之间的差距。在本文中，我们定义了意识的改变状态，讨论了在大脑活动中观察到的意识的相关特征，并引入了全脑模型来探索自下而上的意识改变机制。我们讨论了我们的建议的潜力，鉴于目前的艺术状态，给出了具体的例子，这个研究议程可能会发挥作用，并强调如何通过自下而上的建模改变意识状态的系统调查可以帮助我们更好地了解生物物理，信息和动力学的基础意识。
英文摘要：
The scope of human consciousness includes states departing from what most of us experience as ordinary wakefulness. These altered states of consciousness constitute a prime opportunity to study how global changes in brain activity relate to different varieties of subjective experience. We consider the problem of explaining how global signatures of altered consciousness arise from the interplay between large-scale connectivity and local dynamical rules that can be traced to known properties of neural tissue. For this purpose, we advocate a research program aimed at bridging the gap between bottom-up generative models of whole-brain activity and the top-down signatures proposed by theories of consciousness. Throughout this paper, we define altered states of consciousness, discuss relevant signatures of consciousness observed in brain activity, and introduce whole-brain models to explore the mechanisms of altered consciousness from the bottom-up. We discuss the potential of our proposal in view of the current state of the art, give specific examples of how this research agenda might play out, and emphasise how a systematic investigation of altered states of consciousness via bottom-up modelling may help us better understand the biophysical, informational, and dynamical underpinnings of consciousness.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
