冠状病毒时期更安全的工作空间：抗体检测的新用途
Safer working spaces at coronavirus time: A novel use of antibody tests
摘要：
SARS-CoV-2大流行改变了世界的运作方式。健康问题和人口安全已将各国的经济推向危急状态;因此，在保持工人安全的同时维持经济活动已成为全球目标。在本文中，我们提出了一种新的安全协议的基础上快速抗体检测（ABT）。使用离散事件模拟，我们评估了其性能的累计感染人数的工人，有效的再生数（$R_e$），和活跃的劳动力在一个公司。使用合成实验，我们表明，ABT每周两次（ABT 3）表现最好，检测5.7%的感染工人，相比之下，16.9%，当没有ABT应用。$R_e$从1.75降至0.84，公司内在职员工略有减少。对脱落期的持续时间和ABT的敏感性进行了敏感性分析，得出了相同的定性结论。我们在智利的一家葡萄酒厂应用了该方案：当实施ABT 3方案时，最初的$R_e$估计值为1.3，降低到0.7，感染工人的数量减少了27%。尽管ABT尚未被批准用于COVID-19诊断，但我们的研究表明，升级后的安全标准已经可以在美国实施。
英文摘要：
The SARS-CoV-2 pandemic has transformed the way that the world functions. Health issues and population safety have driven countries' economies to a critical state; therefore, sustaining economic activity while keeping workers safe has become a worldwide goal. In this paper, we present a novel safety protocol based on rapid antibody testing (ABT). Using discrete event simulation, we evaluated its performance on the cumulative number of infected workers, effective reproductive number ($R_e$), and active work force within a company. Using a synthetic experiment, we showed that ABT twice a week (ABT 3) performed the best, detecting 5.7% of infected workers, compared to 16.9% when no ABT was applied. $R_e$ was reduced from 1.75 to 0.84, with a slight decrease in the active workers within the firm. A sensitivity analysis on the duration of the shedding period and sensitivity of ABT was performed and led to the same qualitative conclusions. We applied this protocol in a Chilean winery: the estimation of the initial $R_e$ of 1.3 was reduced to 0.7 when the ABT 3 protocol was implemented, with a 27% decrease in the number of infected workers. Although ABT is not approved for COVID-19 diagnosis, our study shows that upgraded safety standards can already be implemented in workspaces.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
