arXivDaily arXiv每日学术速递 周一至周五更新
arXiv 2005.03868eess.IVcs.LGstat.ML
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基于分层深度卷积神经网络的胃肠道疾病多分类诊断

Hierarchical Deep Convolutional Neural Networks for Multi-category Diagnosis of Gastrointestinal Disorders on Histopathological Images

University of Virginia(弗吉尼亚大学);Queen Mary University of London(伦敦玛丽女王大学);University of Zambia(赞比亚大学);Washington University(华盛顿大学);Aga Khan University(阿迦汗大学)

Rasoul Sali, Sodiq Adewole, Lubaina Ehsan, Lee A. Denson, Paul Kelly, Beatrice C. Amadi, Lori Holtz, Syed Asad Ali, Sean R. Moore, Sana Syed, Donald E. Brown

摘要:

深度卷积神经网络(CNN)在包括图像分类在内的各种计算机视觉任务中取得了成功。该应用的一个特定领域是数字病理学,用于胃肠道(GI)疾病的组织诊断中的模式识别。该领域可以利用CNN将组织病理学图像转化为精确的诊断。这是具有挑战性的,因为这些复杂的活检是异质的,需要多个层次的评估。这主要是由于胃肠道不同部分的结构相似性以及不同肠道疾病之间的共同特征。用一个假设所有类别(肠道的部分及其疾病)都同样难以区分的扁平模型来解决这个问题,会导致对每个类别的评估不足。由于分层模型将分类错误限制在每个子类中,因此它导致比平面模型更具信息量的模型。在本文中,我们提出了应用层次分类的活检图像从不同部分的胃肠道和接受性疾病在每个。我们将类层次结构嵌入到普通的VGGNet中,以利用其层的层次结构。该模型进行了评估,使用一组独立的图像补丁从373个完整的幻灯片图像。结果表明,层次模型可以实现更好的结果比平坦模型的多类别诊断胃肠道疾病的组织病理学图像。

英文摘要:

Deep convolutional neural networks(CNNs) have been successful for a wide range of computer vision tasks, including image classification. A specific area of the application lies in digital pathology for pattern recognition in the tissue-based diagnosis of gastrointestinal(GI) diseases. This domain can utilize CNNs to translate histopathological images into precise diagnostics. This is challenging since these complex biopsies are heterogeneous and require multiple levels of assessment. This is mainly due to structural similarities in different parts of the GI tract and shared features among different gut diseases. Addressing this problem with a flat model that assumes all classes (parts of the gut and their diseases) are equally difficult to distinguish leads to an inadequate assessment of each class. Since the hierarchical model restricts classification error to each sub-class, it leads to a more informative model than a flat model. In this paper, we propose to apply the hierarchical classification of biopsy images from different parts of the GI tract and the receptive diseases within each. We embedded a class hierarchy into the plain VGGNet to take advantage of its layers' hierarchical structure. The proposed model was evaluated using an independent set of image patches from 373 whole slide images. The results indicate that the hierarchical model can achieve better results than the flat model for multi-category diagnosis of GI disorders using histopathological images.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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