面向资源匮乏环境和即时护理的可便携脑部MRI扫描仪
A Portable Brain MRI Scanner for Underserved Settings and Point-Of-Care Imaging
AI总结：
提出一种基于紧凑轻量永磁体的低场便携脑部MRI扫描仪，通过Halbach磁体设计和内置读出梯度场降低成本和基础设施需求，实现资源受限环境下的神经影像诊断。
摘要：
MRI扫描仪的可及性和可用性通常受其成本、场地和基础设施要求的限制。这使得无法被运送到专用扫描套间的患者无法进行MRI诊断（神经系统评估的参考标准），包括危重不稳定患者以及资源匮乏地区的患者。本文提出的扫描仪设计旨在通过大幅减少这些限制来扩展MRI的应用范围。我们的目标是改变MRI的成本效益计算，使其更频繁和多样化地使用，包括提高全球可及性和即时护理操作。在此，我们描述了一种便携式脑部MRI扫描仪，采用紧凑轻量永磁体，并内置读出场梯度。我们的低场（80 mT）Halbach圆柱体设计使用稀土永磁体，产生122 kg的磁体，杂散场极小，既不需要低温也不需要外部电源。内置磁场梯度减少了对高功率梯度驱动器的依赖，这不仅降低了系统总功率和冷却要求，还降低了声学噪声。编码场的不完美通过一种广义迭代图像重建技术来缓解，该技术利用场模式的先验表征。我们的系统通过T1、T2和质子密度加权体内脑图像进行验证，空间分辨率为2.2 x 1.3 x 6.8 mm$^3$。
英文摘要：
Access to and availability of MRI scanners is typically limited by their cost, siting and infrastructure requirements. This precludes MRI diagnostics, the reference standard for neurological assessment, in patients who cannot be transported to specialized scanner suites. This includes patients who are critically ill and unstable, and patients located in low-resource settings. The scanner design presented here aims to extend the reach of MRI by substantially reducing these limitations. Our goal is to shift the cost-benefit calculation for MRI toward more frequent and varied use, including improved accessibility worldwide and point of care operation. Here, we describe a portable brain MRI scanner using a compact, lightweight permanent magnet, with a built-in readout field gradient. Our low-field (80 mT) Halbach cylinder design of rare-earth permanent magnets results in a 122 kg magnet with minimal stray-field, requiring neither cryogenics nor external power. The built-in magnetic field gradient reduces reliance on high-power gradient drivers, which not only lowers overall system power and cooling requirements, but also reduces acoustic noise. Imperfections in the encoding fields are mitigated with a generalized iterative image reconstruction technique, that uses prior characterization of the field patterns. Our system was validated using T1, T2 and proton density weighted in vivo brain images with a spatial resolution of 2.2 x 1.3 x 6.8 mm$^3$.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
