Mammograms are commonly employed in the large scale screening of breast cancer which is primarily characterized by the presence of malignant masses. However, automated image-level detection of malignancy is a challenging task given the small size of the mass regions and difficulty in discriminating between malignant, benign mass and healthy dense fibro-glandular tissue. To address these issues, we explore a two-stage Multiple Instance Learning (MIL) framework. A Convolutional Neural Network (CNN) is trained in the first stage to extract local candidate patches in the mammograms that may contain either a benign or malignant mass. The second stage employs a MIL strategy for an image level benign vs. malignant classification. A global image-level feature is computed as a weighted average of patch-level features learned using a CNN. Our method performed well on the task of localization of masses with an average Precision/Recall of 0.76/0.80 and acheived an average AUC of 0.91 on the imagelevel classification task using a five-fold cross-validation on the INbreast dataset. Restricting the MIL only to the candidate patches extracted in Stage 1 led to a significant improvement in classification performance in comparison to a dense extraction of patches from the entire mammogram.
Breast Tumor Segmentation and Shape Classification in Mammograms using Generative Adversarial and Convolutional Neural Network
Universitat Rovira i Virgili(罗维拉-威尔吉利大学);Bioinformatics Institute, A*STAR(新加坡科技研究局生物信息学研究所);Hospital Universitari Sant Joan de Reus(雷乌斯圣琼大学医院)
寻找乳房肿瘤的乳房X光检查是放射科医生必须经常进行的一项艰巨任务。因此,需要图像分析方法来检测和描绘乳腺肿块,其描绘将支持可靠诊断的关键形态信息。在本文中,我们提出了一个条件生成对抗网络(cGAN)的目的是分割乳腺肿块内的一个区域的兴趣(ROI)在乳房X光片。生成网络学习识别乳房肿块区域并创建勾勒乳房肿块的二进制掩模。反过来,对抗网络学会区分真实(地面真实)和合成分割,从而强制生成网络创建尽可能真实的二进制掩码。即使在训练样本数量有限的情况下,cGAN也能很好地工作。因此,所提出的方法优于几个国家的最先进的方法。这一假设得到了在两个数据集上进行的各种实验的证实,这两个数据集是公共的INbreast和私人的内部数据集。所提出的分割模型分别提供了94%和87%的高Dice系数和Intersection over Union(IoU)。此外,提出了一种基于卷积神经网络(CNN)的形状描述符,将生成的掩模分为四种形状:不规则,小叶,椭圆形和圆形。建议的形状描述符进行训练的数字数据库筛选乳腺摄影(DDSM)产生的总体准确率为80%,这优于目前的最先进的。
AUNet: Attention-guided dense-upsampling networks for breast mass segmentation in whole mammograms
Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences(中国科学院深圳先进技术研究院);Shandong University(山东大学);Guangdong General Hospital(广东省人民医院);Guangdong Academy of Medical Sciences(广东省医学科学院);Shanghai Jiao Tong University(上海交通大学);The University of Sydney(悉尼大学)
Enhancing breast cancer detection on screening mammogram using self-supervised learning and a hybrid deep model of Swin Transformer and Convolutional Neural Network
Physical Sciences, Sunnybrook Research Institute(物理科学,阳光桥研究所在);Medical Biophysics, University of Toronto(医学生物物理,多伦多大学)
The LongiMam model for improved breast cancer risk prediction using longitudinal mammograms
BIOSTAT team, Bordeaux Population Health U1219, Bordeaux University, ISPED, Bordeaux, France(波尔多大学波尔多人口健康中心U1219,ISPED,波尔多,法国);Therapixel, Nice, France(尼斯,法国);Department of Radiology, Institut Bergonié, Comprehensive Cancer Centre, Bordeaux, France(波尔多综合癌症中心,波尔多医院放射科,法国);EPICENE team, Bordeaux Population Health U1219, Bordeaux University, ISPED, Bordeaux, France(波尔多大学波尔多人口健康中心U1219,ISPED,波尔多,法国)
Segmenting Microcalcifications in Mammograms and its Applications
Weizmann Institute of Science(魏茨曼科学研究院);Weizmann Artificial Intelligence Center (WAIC)(魏茨曼人工智能中心);Chaim Sheba Medical Center(查伊姆谢巴医疗中心);Sackler School of Medicine, Tel-Aviv University(特拉维夫大学萨克勒医学院)
MammoMix: Leveraging Mixture of Experts for Robust Mammogram Breast Detection
School of Biomedical Engineering, University of Technology Sydney(悉尼科技大学生物医学工程学院);School of Computer Science, University of Technology Sydney(悉尼科技大学计算机科学学院);School of Electrical and Data Engineering, University of Technology Sydney(悉尼科技大学电气与数据工程学院)
Act Like a Radiologist: Towards Reliable Multi-view Correspondence Reasoning for Mammogram Mass Detection
Deepwise Healthcare(深睿医疗);Peking University(北京大学);Advanced Institute of Information Technology, Peking University(北京大学先进信息技术研究院);The University of Hong Kong(香港大学)
Ordinal Learning: Longitudinal Attention Alignment Model for Predicting Time to Future Breast Cancer Events from Mammograms
Netherlands Cancer Institute (NKI)(荷兰癌症研究所);GROW School for Oncology and Development Biology, Maastricht University(马斯特里赫特大学GROW肿瘤学与发育生物学学院);Macao Polytechnic University(澳门理工大学);Radboud University Medical Centre(拉德堡德大学医学中心)
The Impact of Longitudinal Mammogram Alignment on Breast Cancer Risk Assessment
Department of Physics and Technology, UiT The Arctic University of Norway(乌伊特极地大学物理与技术系);SPKI The Norwegian Centre for Clinical Artificial Intelligence, University Hospital of North Norway(挪威临床人工智能中心,北挪威大学医院);Department of Computer Science and Engineering, University of Bologna(博洛尼亚大学计算机科学与工程系);Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering IMTE(弗劳恩霍夫个性化与细胞基医学工程研究所);Department of Radiology, Netherlands Cancer Institute (NKI)(荷兰癌症研究所放射科);Norwegian Computing Center(挪威计算中心);Pioneer Centre for AI, University of Copenhagen(人工智能先锋中心,哥本哈根大学)
MammoDG: Generalisable Deep Learning Breaks the Limits of Cross-Domain Multi-Center Breast Cancer Screening
University of Cambridge(剑桥大学);The Hong Kong University of Science and Technology (Guangzhou)(香港科技大学(广州));The Hong Kong Polytechnic University(香港理工大学);Barts Health NHS Trust(巴茨健康国民保健服务信托);The Royal London Hospital(皇家伦敦医院)
A Versatile Foundation Model for AI-enabled Mammogram Interpretation
Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Department of Medical Oncology, Breast Tumor Centre, Phase I Clinical Trial Centre(广东省恶性肿瘤表观遗传与基因调控重点实验室,粤港澳RNA医学联合实验室,医学肿瘤科,乳腺肿瘤中心,I期临床试验中心);Guangdong Provincial Key Laboratory of Cancer Pathogenesis and Precision Diagnosis and Treatment, AI Big Data Laboratory, Department of Medical Oncology(广东省肿瘤发生与精准诊断与治疗重点实验室,人工智能大数据实验室,医学肿瘤科);Chongqing Key Laboratory of Bio-perception(重庆生物感知重点实验室)
A New Computer-Aided Diagnosis System with Modified Genetic Feature Selection for BI-RADS Classification of Breast Masses in Mammograms
Beijing Institute of Technology(北京理工大学);Université 8 Mai 1945 Guelma(盖勒马8 Mai 1945大学);National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College(中国医学科学院北京协和医学院肿瘤医院国家癌症中心国家肿瘤临床研究中心)