Ptychography has rapidly grown in the fields of X-ray and electron imaging for its unprecedented ability to achieve nano or atomic scale resolution while simultaneously retrieving chemical or magnetic information from a sample. A ptychographic reconstruction is achieved by means of solving a complex inverse problem that imposes constraints both on the acquisition and on the analysis of the data, which typically precludes real-time imaging due to computational cost involved in solving this inverse problem. In this work we propose PtychoNN, a novel approach to solve the ptychography reconstruction problem based on deep convolutional neural networks. We demonstrate how the proposed method can be used to predict real-space structure and phase at each scan point solely from the corresponding far-field diffraction data. The presented results demonstrate how PtychoNN can effectively be used on experimental data, being able to generate high quality reconstructions of a sample up to hundreds of times faster than state-of-the-art ptychography reconstruction solutions once trained. By surpassing the typical constraints of iterative model-based methods, we can significantly relax the data acquisition sampling conditions and produce equally satisfactory reconstructions. Besides drastically accelerating acquisition and analysis, this capability can enable new imaging scenarios that were not possible before, in cases of dose sensitive, dynamic and extremely voluminous samples.
We report a compact, cost-effective and field-portable lensless imaging platform for quantitative microscopy. In this platform, the object is placed on top of an image sensor chip without using any lens. We use a low-cost galvo scanner to rapidly scan an unknown laser speckle pattern on the object. To address the positioning repeatability and accuracy issues, we directly recover the positional shifts of the speckle pattern based on the phase correlation of the captured images. To bypass the resolution limit set by the imager pixel size, we employ a sub-sampled ptychographic phase retrieval pro…
Fourier ptychographic microscopy (FPM) is a computational imaging technique with both high resolution and large field-of-view. However, the effective numerical aperture (NA) achievable with a typical LED panel is ambiguous and usually relies on the repeated tests of different illumination NAs. The imaging quality of each raw image usually depends on the visual assessments, which is subjective and inaccurate especially for those dark field images. Moreover, the acquisition process is really time-consuming.In this paper, we propose a SNR-based adaptive acquisition method for quantitative evaluat…
Image reconstruction is an inverse problem that solves for a computational image based on sampled sensor measurement. Sparsely sampled image reconstruction poses addition challenges due to limited measurements. In this work, we propose an implicit Neural Representation learning methodology with Prior embedding (NeRP) to reconstruct a computational image from sparsely sampled measurements. The method differs fundamentally from previous deep learning-based image reconstruction approaches in that NeRP exploits the internal information in an image prior, and the physics of the sparsely sampled mea…
Sparse-view computed tomography (CT) can be used to reduce radiation dose greatly but is suffers from severe image artifacts. Recently, the deep learning based method for sparse-view CT reconstruction has attracted a major attention. However, neural networks often have a limited ability to remove the artifacts when they only work in the image domain. Deep learning-based sinogram processing can achieve a better anti-artifact performance, but it inevitably requires feature maps of the whole image in a video memory, which makes handling large-scale or three-dimensional (3D) images rather challeng…
Wellcome / EPSRC Centre for Interventional and Surgical Sciences, University College London（伦敦大学学院威康/EPSRC介入与外科学中心）；University College London（伦敦大学学院）
Purpose: Probe-based Confocal Laser Endomicroscopy (pCLE) enables performing an optical biopsy, providing real-time microscopic images, via a probe. pCLE probes consist of multiple optical fibres arranged in a bundle, which taken together generate signals in an irregularly sampled pattern. Current pCLE reconstruction is based on interpolating irregular signals onto an over-sampled Cartesian grid, using a naive linear interpolation. It was shown that Convolutional Neural Networks (CNNs) could improve pCLE image quality. Although classical CNNs were applied to pCLE, input data were limited to re…
The Image-Based Rendering (IBR) approach using Shearlet Transform (ST) is one of the most effective methods for Densely-Sampled Light Field (DSLF) reconstruction. The ST-based DSLF reconstruction typically relies on an iterative thresholding algorithm for Epipolar-Plane Image (EPI) sparse regularization in shearlet domain, involving dozens of transformations between image domain and shearlet domain, which are in general time-consuming. To overcome this limitation, a novel learning-based ST approach, referred to as Deep Residual Shearlet Transform (DRST), is proposed in this paper. Specifically…
Accelerated deep self-supervised ptycho-laminography for three-dimensional nanoscale imaging of integrated circuits
Massachusetts Institute of Technology（麻省理工学院）；Argonne National Laboratory（阿贡国家实验室）；Paul Scherrer Institut（保罗·谢勒研究所）；Ecole Polytechnique Fédérale de Lausanne（洛桑联邦理工学院）；University of Southern California（南加州大学）；Singapore-MIT Alliance for Research and Technology（新加坡-麻省理工研究与技术联盟）；University of California, Berkeley（加州大学伯克利分校）
City University of Hong Kong（香港城市大学）；Hong Kong Baptist University（香港浸会大学）；Huaqiao University（华侨大学）；ShanghaiTech University（上海科技大学）
A densely-sampled light field (LF) is highly desirable in various applications, such as 3-D reconstruction, post-capture refocusing and virtual reality. However, it is costly to acquire such data. Although many computational methods have been proposed to reconstruct a densely-sampled LF from a sparsely-sampled one, they still suffer from either low reconstruction quality, low computational efficiency, or the restriction on the regularity of the sampling pattern. To this end, we propose a novel learning-based method, which accepts sparsely-sampled LFs with irregular structures, and produces den…
Current deep learning approaches for diffusion MRI modeling circumvent the need for densely-sampled diffusion-weighted images (DWIs) by directly predicting microstructural indices from sparsely-sampled DWIs. However, they implicitly make unrealistic assumptions of static $q$-space sampling during training and reconstruction. Further, such approaches can restrict downstream usage of variably sampled DWIs for usages including the estimation of microstructural indices or tractography. We propose a generative adversarial translation framework for high-quality DWI synthesis with arbitrary $q$-space…
HierGF: Hierarchical Gaussian Fields via Geometry-perception Message Passing for Sparse-view 3D Reconstruction
Wangxuan Institute of Computer Technology, Peking University（北京大学王选计算机研究所）；Institute for Math & AI, Wuhan University（武汉大学数学与人工智能研究院）；School of Intelligence Science and Technology, Peking University（北京大学智能科学与技术学院）
There exist many scenarios where pixel information is available only on a non-regular subset of pixel positions. For further processing, however, it is required to reconstruct such images on a regular grid. Besides many other algorithms, frequency selective reconstruction can be applied for this task. It performs a block-wise generation of a sparse signal model as an iterative superposition of Fourier basis functions and uses this model to replace missing or corrupted pixels in an image. In this paper, it is shown that it is not required to spend the same amount of iterations on both homogeneo…
Compressed sensing (CS) is a powerful method routinely employed to accelerate image acquisition. It is particularly suited to situations when the image under consideration is sparse but can be sampled in a basis where it is non-sparse. Here we propose an alternate CS regime in situations where the image can be sampled in two incoherent spaces simultaneously, with a special focus on image sampling in Fourier reciprocal spaces (e.g. real-space and k-space). Information is fed-forward from one space to the other, allowing new opportunities to efficiently solve the optimization problem at the hear…
Recently, a number of approaches to low-dose computed tomography (CT) have been developed and deployed in commercialized CT scanners. Tube current reduction is perhaps the most actively explored technology with advanced image reconstruction algorithms. Sparse data sampling is another viable option to the low-dose CT, and sparse-view CT has been particularly of interest among the researchers in CT community. Since analytic image reconstruction algorithms would lead to severe image artifacts, various iterative algorithms have been developed for reconstructing images from sparsely view-sampled pr…
Towards Large-scale Single-shot Millimeter-wave Imaging for Low-cost Security Inspection
Beijing Institute of Technology（北京理工大学）；Yanotze Delta Region Academy of Beijing Institute of Technology (Jiaxing)（北京理工大学长三角研究院（嘉兴））；Tangshan Research Institute of Beijing Institute of Technology（北京理工大学唐山研究院）
Northwestern University（西北大学）；University of Erlangen-Nuremberg（埃尔朗根-纽伦堡大学）
Computed tomography is widely used to examine internal structures in a non-destructive manner. To obtain high-quality reconstructions, one typically has to acquire a densely sampled trajectory to avoid angular undersampling. However, many scenarios require a sparse-view measurement leading to streak-artifacts if unaccounted for. Current methods do not make full use of the domain-specific information, and hence fail to provide reliable reconstructions for highly undersampled data. We present a novel framework for sparse-view tomography by decoupling the reconstruction into two steps: First, we …
