The Regression Discontinuity Design (RDD) is a quasi-experimental design that estimates the causal effect of a treatment when its assignment is defined by a threshold value for a continuous assignment variable. The RDD assumes that subjects with measurements within a bandwidth around the threshold belong to a common population, so that the threshold can be seen as a randomising device assigning treatment to those falling just above the threshold and withholding it from those who fall just below.
Bandwidth selection represents a compelling decision for the RDD analysis as the results may be highly sensitive to its choice. A number of methods to select the optimal bandwidth, mainly originating from the econometric literature, have been proposed. However, their use in practice is limited.
We propose a methodology that, tackling the problem from an applied point of view, consider units' exchangeability, i.e., their similarity with respect to measured covariates, as the main criteria to select subjects for the analysis, irrespectively of their distance from the threshold. We carry out clustering on the sample using a Dirichlet process mixture model to identify balanced and homogeneous clusters. Our proposal exploits the posterior similarity matrix, which contains the pairwise probabilities that two observations are allocated to the same cluster in the MCMC sample. Thus we include in the RDD analysis only those clusters for which we have stronger evidence of exchangeability.
We illustrate the validity of our methodology with both a simulated experiment and a motivating example on the effect of statins to lower cholesterol level, using UK primary care data.
The modelling of action potentials from extracellular recordings, or spike sorting, is a rich area of neuroscience research in which latent variable models are often used. Two such models, Overfitted Finite Mixture models (OFMs) and Dirichlet Process Mixture models (DPMs) are considered to provide insights for unsupervised clustering of complex, multivariate medical data when the number of clusters is unknown. OFM and DPM are structured in a similar hierarchical fashion but they are based on different philosophies with different underlying assumptions. This study investigates how these differe…
We propose Dirichlet Process Mixture (DPM) models for prediction and cluster-wise variable selection, based on two choices of shrinkage baseline prior distributions for the linear regression coefficients, namely the Horseshoe prior and Normal-Gamma prior. We show in a simulation study that each of the two proposed DPM models tend to outperform the standard DPM model based on the non-shrinkage normal prior, in terms of predictive, variable selection, and clustering accuracy. This is especially true for the Horseshoe model, and when the number of covariates exceeds the within-cluster sample size…
In this paper we propose a model with a Dirichlet process mixture of gamma densities in the bulk part below threshold and a generalized Pareto density in the tail for extreme value estimation. The proposed model is simple and flexible allowing us posterior density estimation and posterior inference for high quantiles. The model works well even for small sample sizes and in the absence of prior information. We evaluate the performance of the proposed model through a simulation study. Finally, the proposed model is applied to a real environmental data.
Spatially referenced data are increasingly available thanks to the development of modern GPS technology. They also provide rich opportunities for spatial analytics in the field of marketing science. Our main interest is to propose a new efficient statistical framework to conduct spatial segmentation analysis for restaurants located in a metropolitan area in the U.S. The spatial segmentation problem poses important statistical challenges: selecting the optimal number of underlying structures of market segments, capturing complex and flexible spatial structures, and resolving any possible small …
In this paper, we provide an explicit probability distribution for classification purposes. It is derived from the Bayesian nonparametric mixture of Dirichlet process model, but with suitable modifications which remove unsuitable aspects of the classification based on this model. The resulting approach then more closely resembles a classical hierarchical grouping rule in that it depends on sums of squares of neighboring values. The proposed probability model for classification relies on a simulation algorithm which will be based on a reversible MCMC algorithm for determining the probabilities,…
Understanding the spatio-temporal patterns of the coronavirus disease 2019 (COVID-19) is essential to construct public health interventions. Spatially referenced data can provide richer opportunities to understand the mechanism of the disease spread compared to the more often encountered aggregated count data. We propose a spatio-temporal Dirichlet process mixture model to analyze confirmed cases of COVID-19 in an urban environment. Our method can detect unobserved cluster centers of the epidemics, and estimate the space-time range of the clusters that are useful to construct a warning system.…
Dust particles recovered from the soles of shoes may be indicative of the sites recently visited by an individual, and, in particular, of the presence of an individual at a particular site of interest, e.g., the scene of a crime. By describing the dust profile of a given site by a multinomial distribution over a fixed number of dust particle types, we can define the probability distribution of the mixture of dust recovered from the sole of a shoe via Latent Dirichlet Allocation. We use Variational Bayesian Inference to study the parameters of the model, and use their resulting posterior distri…
Studying the human microbiome has gained substantial interest in recent years, and a common task in the analysis of these data is to cluster microbiome compositions into subtypes. This subdivision of samples into subgroups serves as an intermediary step in achieving personalized diagnosis and treatment. In applying existing clustering methods to modern microbiome studies including the American Gut Project (AGP) data, we found that this seemingly standard task, however, is very challenging in the microbiome composition context due to several key features of such data. Standard distance-based cl…
We present a mixed multinomial logit (MNL) model, which leverages the truncated stick-breaking process representation of the Dirichlet process as a flexible nonparametric mixing distribution. The proposed model is a Dirichlet process mixture model and accommodates discrete representations of heterogeneity, like a latent class MNL model. Yet, unlike a latent class MNL model, the proposed discrete choice model does not require the analyst to fix the number of mixture components prior to estimation, as the complexity of the discrete mixing distribution is inferred from the evidence. For posterior…
Dirichlet Process Mixture (DPM) models have been increasingly employed to specify random partition models that take into account possible patterns within the covariates. Furthermore, to deal with large numbers of covariates, methods for selecting the most important covariates have been proposed. Commonly, the covariates are chosen either for their importance in determining the clustering of the observations or for their effect on the level of a response variable (when a regression model is specified). Typically both strategies involve the specification of latent indicators that regulate the in…
The Dirichlet Process (DP) mixture model has become a popular choice for model-based clustering, largely because it allows the number of clusters to be inferred. The sequential updating and greedy search (SUGS) algorithm (Wang and Dunson, 2011) was proposed as a fast method for performing approximate Bayesian inference in DP mixture models, by posing clustering as a Bayesian model selection (BMS) problem and avoiding the use of computationally costly Markov chain Monte Carlo methods. Here we consider how this approach may be extended to permit variable selection for clustering, and also demons…
Wind energy production is very sensitive to instantaneous wind speed fluctuations. Thus rapid variation of wind speed due to changes in the local meteorological conditions can lead to electrical power variations of the order of the nominal power output. In small grids, as they exist for example on some islands in the French West Indies, such fluctuations can cause instabilities in case of intermediate power shortages. To palliate these difficulties, it is essential to identify and characterize the wind speed distributions. This allows to anticipate the eventuality of power shortage or power su…
We present a margin-free finite mixture model which allows us to simultaneously classify objects into known classes and to identify possible new object types using a set of continuous attributes. This application is motivated by the needs of identifying and possibly detecting new types of a particular kind of stars known as variable stars. We first suitably transform the physical attributes of the stars onto the simplex to achieve scale invariance while maintaining their dependence structure. This allows us to compare data collected by different sky surveys which can have different scales. The…
The rise of "big data" has led to the frequent need to process and store datasets containing large numbers of high dimensional observations. Due to storage restrictions, these observations might be recorded in a lossy-but-sparse manner, with information collapsed onto a few entries which are considered important. This results in informative missingness in the observed data. Our motivating application comes from retail analytics, where the behaviour of product sales is summarised by the price elasticity of each product with respect to a small number of its top competitors. The resulting data ar…
We address the problem of retrieving relevant experiments given a query experiment, motivated by the public databases of datasets in molecular biology and other experimental sciences, and the need of scientists to relate to earlier work on the level of actual measurement data. Since experiments are inherently noisy and databases ever accumulating, we argue that a retrieval engine should possess two particular characteristics. First, it should compare models learnt from the experiments rather than the raw measurements themselves: this allows incorporating experiment-specific prior knowledge to …
By providing new insights into the distribution of a protein's torsion angles, recent statistical models for this data have pointed the way to more efficient methods for protein structure prediction. Most current approaches have concentrated on bivariate models at a single sequence position. There is, however, considerable value in simultaneously modeling angle pairs at multiple sequence positions in a protein. One area of application for such models is in structure prediction for the highly variable loop and turn regions. Such modeling is difficult due to the fact that the number of known pro…
Choose A Table: Tensor Dirichlet Process Multinomial Mixture Model with Graphs for Passenger Trajectory Clustering
University of Cologne（科隆大学）；Arizona State University（亚利桑那州立大学）；Tsinghua University（清华大学）；McGill University（麦吉尔大学）；The Hong Kong University of Science and Technology（香港科技大学）；HKUST-GZ（香港科技大学（广州））
The perennial problem of "how many clusters?" remains an issue of substantial interest in data mining and machine learning communities, and becomes particularly salient in large data sets such as populational genomic data where the number of clusters needs to be relatively large and open-ended. This problem gets further complicated in a co-clustering scenario in which one needs to solve multiple clustering problems simultaneously because of the presence of common centroids (e.g., ancestors) shared by clusters (e.g., possible descents from a certain ancestor) from different multiple-cluster sam…
