arXiv 2003.104052020-03physics.med-ph

米兰机械呼吸机（MVM）：一种为应对COVID-19大流行而设计的大规模生产的新型机械呼吸机

Mechanical Ventilator Milano (MVM): A Novel Mechanical Ventilator Designed for Mass Scale Production in Response to the COVID-19 Pandemic

C. Galbiati, A. Abba, P. Agnes, P. Amaudruz, M. Arba, F. Ardellier-Desages, C. Badia, G. Batignani, G. Bellani, G. Bianchi, D. Bishop, V. Bocci, W. Bonivento, B… 展开作者

C. Galbiati, A. Abba, P. Agnes, P. Amaudruz, M. Arba, F. Ardellier-Desages, C. Badia, G. Batignani, G. Bellani, G. Bianchi, D. Bishop, V. Bocci, W. Bonivento, B. Bottino, M. Bouchard, S. Brice, G. Buccino, S. Bussino, A. Caminata, A. Capra, M. Caravati, M. Carlini, L. Carrozzi, J. M. Cela, B. Celano, C. Charette, S. Coelli, M. Constable, V. Cocco, G. Croci, S. Cudmore, A. Dal Molin, S. D'Auria, G. D'Avenio, J. DeRuiter, S. De Cecco, L. De Lauretis, M. Del Tutto, A. Devoto, T. Dinon, E. Druszkiewicz, A. Fabbri, F. Ferroni, G. Fiorillo, R. Ford, G. Foti, D. Franco, F. Gabriele, P. Garcia Abia, L. S. Giarratana, J. Givoletti, Mi. Givoletti, G. Gorini, E. Gramellini, G. Grosso, F. Guescini, E. Guetre, T. Hadden, J. Hall, A. Heavey, G. Hersak, N. Hessey, An. Ianni, C. Ienzi, V. Ippolito, C. L. Kendziora, M. King, A. Kittmer, I. Kochanek, R. Kruecken, M. La Commara, G. Leblond, X. Li, C. Lim, T. Lindner, T. Lombardi, T. Long, P. Lu, G. Lukhanin, G. Magni, R. Maharaj, M. Malosio, C. Mapelli, P. Maqueo, P. Margetak, S. M. Mari, L. Martin, N. Massacret, A. McDonald, D. Minuzzo, T. A. Mohayai, L. Molinari Tosatti, C. Moretti, A. Muraro, F. Nati, A. J. Noble, A. Norrick, K. Olchanski, I. Palumbo, R. Paoletti, N. Paoli, C. Pearson, C. Pellegrino, V. Pesudo, A. Pocar, M. Pontesilli, R. Pordes, S. Pordes, A. Prini, O. Putignano, J. L. Raaf, M. Razeti, A. Razeto, D. Reed, A. Renshaw, M. Rescigno, F. Retiere, L. P. Rignanese, J. Rode, L. J. Romualdez, R. Santorelli, D. Sablone, E. Scapparone, T. Schaubel, B. Shaw, A. S. Slutsky, B. Smith, N. J. T. Smith, P. Spagnolo, F. Spinella, A. Stenzler, A. Steri, L. Stiaccini, C. Stoughton, P. Stringari, M. Tardocchi, R. Tartaglia, G. Testera, C. Tintori, A. Tonazzo, J. Tseng, E. Viscione, F. Vivaldi, M. Wada, H. Wang, S. Westerdale, S. Yue, A. Zardoni

发表信息：: Phys.Fluids 33 (2021) 3, 037122
DOI：: 10.1063/5.0044445

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摘要：

这里介绍的是米兰机械呼吸机（MVM）的设计，这是一种新型机械呼吸机，旨在应对COVID-19大流行，以解决许多国家重症治疗呼吸机的紧急短缺，以及通过正常供应链跨境采购这些设备越来越困难的问题。该呼吸机是一个机电等效的旧的和可靠的曼利呼吸机，并能够在压力控制和压力支持通气模式。由于与前线医生的合作，MVM针对COVID-19紧急情况进行了优化。MVM是为在短时间内以有限的成本进行大规模生产而设计的，因为它依赖于现成的组件，在世界各地都可以买到。MVM的操作仅需要压缩氧气（或压缩医用空气）源和电源。初步测试的原型设备与呼吸模拟器。进一步的测试和开发正在进行中。在此阶段，MVM尚未成为认证医疗器械，但认证正在进行中。

英文摘要：

Presented here is the design of the Mechanical Ventilator Milano (MVM), a novel mechanical ventilator designed for rapid mass production in response to the COVID-19 pandemic to address the urgent shortage of intensive therapy ventilators in many countries, and the growing difficulty in procuring these devices through normal supply chains across borders. This ventilator is an electro-mechanical equivalent of the old and reliable Manley Ventilator, and is able to operate in both pressure-controlled and pressure-supported ventilation modes. MVM is optimized for the COVID-19 emergency, thanks to the collaboration with medical doctors in the front line. MVM is designed for large-scale production in a short amount of time and at a limited cost, as it relays on off-the-shelf components, readily available worldwide. Operation of the MVM requires only a source of compressed oxygen (or compressed medical air) and electrical power. Initial tests of a prototype device with a breathing simulator are also presented. Further tests and developments are underway. At this stage the MVM is not yet a certified medical device but certification is in progress.

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