Kidney volume is greatly affected in several renal diseases. Precise and automatic segmentation of the kidney can help determine kidney size and evaluate renal function. Fully convolutional neural networks have been used to segment organs from large biomedical 3D images. While these networks demonstrate state-of-the-art segmentation performances, they do not immediately translate to small foreground objects, small sample sizes, and anisotropic resolution in MRI datasets. In this paper we propose a new framework to address some of the challenges for segmenting 3D MRI. These methods were implemented on preclinical MRI for segmenting kidneys in an animal model of lupus nephritis. Our implementation strategy is twofold: 1) to utilize additional MRI diffusion images to detect the general kidney area, and 2) to reduce the 3D U-Net kernels to handle small sample sizes. Using this approach, a Dice similarity coefficient of 0.88 was achieved with a limited dataset of n=196. This segmentation strategy with careful optimization can be applied to various renal injuries or other organ systems.
NVIDIA（英伟达）；University of California, Los Angeles（加州大学洛杉矶分校）
Automated segmentation of kidneys and kidney tumors is an important step in quantifying the tumor's morphometrical details to monitor the progression of the disease and accurately compare decisions regarding the kidney tumor treatment. Manual delineation techniques are often tedious, error-prone and require expert knowledge for creating unambiguous representation of kidneys and kidney tumors segmentation. In this work, we propose an end-to-end boundary aware fully Convolutional Neural Networks (CNNs) for reliable kidney and kidney tumor semantic segmentation from arterial phase abdominal 3D CT…
Couger Inc（库格公司）；Sethu Institute of Technology（塞图理工学院）；Thiagarajar college of Engineering（蒂亚加拉贾工程学院）
KiTs19 challenge paves the way to haste the improvement of solid kidney tumor semantic segmentation methodologies. Accurate segmentation of kidney tumor in computer tomography (CT) images is a challenging task due to the non-uniform motion, similar appearance and various shape. Inspired by this fact, in this manuscript, we present a novel kidney tumor segmentation method using deep learning network termed as Hyper vision Net model. All the existing U-net models are using a modified version of U-net to segment the kidney tumor region. In the proposed architecture, we introduced supervision laye…
Kidney structures segmentation is a crucial yet challenging task in the computer-aided diagnosis of surgery-based renal cancer. Although numerous deep learning models have achieved remarkable success in many medical image segmentation tasks, accurate segmentation of kidney structures on computed tomography angiography (CTA) images remains challenging, due to the variable sizes of kidney tumors and the ambiguous boundaries between kidney structures and their surroundings. In this paper, we propose a boundary-aware network (BA-Net) to segment kidneys, kidney tumors, arteries, and veins on CTA sc…
U-Net has achieved huge success in various medical image segmentation challenges. Kinds of new architectures with bells and whistles might succeed in certain dataset when employed with optimal hyper-parameter, but their generalization always can't be guaranteed. Here, we focused on the basic U-Net architecture and proposed a multi scale supervised 3D U-Net for the segmentation task in KiTS19 challenge. To enhance the performance, our work can be summarized as three folds: first, we used multi scale supervision in the decoder pathway, which could encourage the network to predict right results f…
Image Sciences Institute, UMC Utrecht, Utrecht University（乌得勒支大学医学中心影像科学研究所）
This paper assesses whether using clinical characteristics in addition to imaging can improve automated segmentation of kidney cancer on contrast-enhanced computed tomography (CT). A total of 300 kidney cancer patients with contrast-enhanced CT scans and clinical characteristics were included. A baseline segmentation of the kidney cancer was performed using a 3D U-Net. Input to the U-Net were the contrast-enhanced CT images, output were segmentations of kidney, kidney tumors, and kidney cysts. A cognizant sampling strategy was used to leverage clinical characteristics for improved segmentation…
Nigerian Defence Academy（尼日利亚国防学院）；University of Maiduguri（迈杜古里大学）；Federal University Dutsinma（杜钦马联邦大学）
Deep neural Network (DNN) is becoming a focal point in Machine Learning research. Its application is penetrating into different fields and solving intricate and complex problems. DNN is now been applied in health image processing to detect various ailment such as cancer and diabetes. Another disease that is causing threat to our health is the kidney disease. This disease is becoming prevalent due to substances and elements we intake. Death is imminent and inevitable within few days without at least one functioning kidney. Ignoring the kidney malfunction can cause chronic kidney disease leading…
Umeå University（于默奥大学）；Eindhoven University of Technology（埃因霍温理工大学）
Kidney tumor segmentation emerges as a new frontier of computer vision in medical imaging. This is partly due to its challenging manual annotation and great medical impact. Within the scope of the Kidney Tumor Segmentation Challenge 2019, that is aiming at combined kidney and tumor segmentation, this work proposes a novel combination of 3D U-Nets---collectively denoted TuNet---utilizing the resulting kidney masks for the consecutive tumor segmentation. The proposed method achieves a Sørensen-Dice coefficient score of 0.902 for the kidney, and 0.408 for the tumor segmentation, computed from a f…
College of Biomedical Engineering, Rangsit University（兰实大学生物医学工程学院）
Automated medical image segmentation is a priority research area for computational methods. In particular, detection of cancerous tumors represents a current challenge in this area with potential for real-world impact. This paper describes a method developed in response to the 2019 Kidney Tumor Segmentation Challenge (KiTS19). Axial computed tomography (CT) scans from 210 kidney cancer patients were used to develop and evaluate this automatic segmentation method based on a logical ensemble of fully-convolutional network (FCN) architectures, followed by volumetric validation. Data was pre-proce…
Institute of Computing Technology, Chinese Academy of Sciences（中国科学院计算技术研究所）；University of Chinese Academy of Sciences（中国科学院大学）；Southeast University（东南大学）；Lenovo Research（联想研究院）
Automated segmentation of kidney and tumor from 3D CT scans is necessary for the diagnosis, monitoring, and treatment planning of the disease. In this paper, we describe a two-stage framework for kidney and tumor segmentation based on 3D fully convolutional network (FCN). The first stage preliminarily locate the kidney and cut off the irrelevant background to reduce class imbalance and computation cost. Then the second stage precisely segment the kidney and tumor on the cropped patch. The proposed method ranks the 4th place out of 105 competitive teams in MICCAI 2019 KiTS Challenge with a Comp…
Accurate segmentation of kidneys and kidney tumors is an essential step for radiomic analysis as well as developing advanced surgical planning techniques. In clinical analysis, the segmentation is currently performed by clinicians from the visual inspection images gathered through a computed tomography (CT) scan. This process is laborious and its success significantly depends on previous experience. Moreover, the uncertainty in the tumor location and heterogeneity of scans across patients increases the error rate. To tackle this issue, computer-aided segmentation based on deep learning techniq…
ARTORG Center for Biomedical Engineering Research, University of Bern（伯尔尼大学生物医学工程研究中心）
Each year, there are about 400'000 new cases of kidney cancer worldwide causing around 175'000 deaths. For clinical decision making it is important to understand the morphometry of the tumor, which involves the time-consuming task of delineating tumor and kidney in 3D CT images. Automatic segmentation could be an important tool for clinicians and researchers to also study the correlations between tumor morphometry and clinical outcomes. We present a segmentation method which combines the popular U-Net convolutional neural network architecture with post-processing based on statistical constrain…
Technical University of Kosice（科希策工业大学）；Pavol Jozef Safarik University（帕沃尔·约瑟夫·沙法里克大学）；Louis Pasteur University Hospital（路易斯·巴斯德大学医院）
The kidney cancer is one of the most common cancer types. The treatment frequently include surgical intervention. However, surgery is in this case particularly challenging due to regional anatomical relations. Organ delineation can significantly improve surgical planning and execution. In this contribution, we propose ensemble of two fully convolutional networks for segmentation of kidney, tumor, veins and arteries. While SegResNet architecture achieved better performance on tumor, the nnU-Net provided more precise segmentation for kidneys, arteries and veins. So in our proposed approach we co…
Automatic segmentation of kidney and kidney tumour in Computed Tomography (CT) images is essential, as it uses less time as compared to the current gold standard of manual segmentation. However, many hospitals are still reliant on manual study and segmentation of CT images by medical practitioners because of its higher accuracy. Thus, this study focuses on the development of an approach for automatic kidney and kidney tumour segmentation in contrast-enhanced CT images. A method based on Convolutional Neural Network (CNN) was proposed, where a 3D U-Net segmentation model was developed and train…
A Two-Step Deep Learning Method for 3DCT-2DUS Kidney Registration During Breathing
Institute for Infocomm Research (I2R), Agency for Science, Technology and Research (A*STAR)（信息通信研究院（I2R），新加坡科学、技术与研究局（A*STAR））；The Fifth Affiliated Hospital of Guangzhou Medical University（广州医科大学附属第五医院）；Creative Medtech Solutions Pte Ltd（创意医疗科技解决方案私人有限公司）
Precise characterization of the kidney and kidney tumor characteristics is of outmost importance in the context of kidney cancer treatment, especially for nephron sparing surgery which requires a precise localization of the tissues to be removed. The need for accurate and automatic delineation tools is at the origin of the KiTS19 challenge. It aims at accelerating the research and development in this field to aid prognosis and treatment planning by providing a characterized dataset of 300 CT scans to be segmented. To address the challenge, we proposed an automatic, multi-stage, 2.5D deep learn…
German Cancer Research Center (DKFZ)（德国癌症研究中心（DKFZ））；University of Heidelberg（海德堡大学）
The U-Net is arguably the most successful segmentation architecture in the medical domain. Here we apply a 3D U-Net to the 2019 Kidney and Kidney Tumor Segmentation Challenge and attempt to improve upon it by augmenting it with residual and pre-activation residual blocks. Cross-validation results on the training cases suggest only very minor, barely measurable improvements. Due to marginally higher dice scores, the residual 3D U-Net is chosen for test set prediction. With a Composite Dice score of 91.23 on the test set, our method outperformed all 105 competing teams and won the KiTS2019 chall…
Uppsala University（乌普萨拉大学）；Antaros Medical AB（安塔罗斯医疗公司）
The UK Biobank is collecting extensive data on health-related characteristics of over half a million volunteers. The biological samples of blood and urine can provide valuable insight on kidney function, with important links to cardiovascular and metabolic health. Further information on kidney anatomy could be obtained by medical imaging. In contrast to the brain, heart, liver, and pancreas, no dedicated Magnetic Resonance Imaging (MRI) is planned for the kidneys. An image-based assessment is nonetheless feasible in the neck-to-knee body MRI intended for abdominal body composition analysis, wh…
Three-dimensional (3D) kidney parsing on computed tomography angiography (CTA) images is of great clinical significance. Automatic segmentation of kidney, renal tumor, renal vein and renal artery benefits a lot on surgery-based renal cancer treatment. In this paper, we propose a new nnhra-unet network, and use a multi-stage framework which is based on it to segment the multi-structure of kidney and participate in the KiPA2022 challenge.
Vanderbilt University（范德堡大学）；Vanderbilt University Medical Center（范德堡大学医学中心）
Image segmentation has been increasingly applied in medical settings as recent developments have skyrocketed the potential applications of deep learning. Urology, specifically, is one field of medicine that is primed for the adoption of a real-time image segmentation system with the long-term aim of automating endoscopic stone treatment. In this project, we explored supervised deep learning models to annotate kidney stones in surgical endoscopic video feeds. In this paper, we describe how we built a dataset from the raw videos and how we developed a pipeline to automate as much of the process …
James Cook University（詹姆斯·库克大学）；Mahidol University（玛希隆大学）；University of Bremen（不来梅大学）
Automatic segmentation of hepatic lesions in computed tomography (CT) images is a challenging task to perform due to heterogeneous, diffusive shape of tumors and complex background. To address the problem more and more researchers rely on assistance of deep convolutional neural networks (CNN) with 2D or 3D type architecture that have proven to be effective in a wide range of computer vision tasks, including medical image processing. In this technical report, we carry out research focused on more careful approach to the process of learning rather than on complex architecture of the CNN. We have…
Graduate School of Information Science, Nagoya University（名古屋大学信息科学研究生院）；Graduate School of Informatics, Nagoya University（名古屋大学信息学院研究生院）；School of Information Science, Aichi Institute of Technology（爱知工业大学信息学院）；Nagoya University Graduate School of Medicine（名古屋大学医学研究生院）
This paper presents a new approach for precisely estimating the renal vascular dominant region using a Voronoi diagram. To provide computer-assisted diagnostics for the pre-surgical simulation of partial nephrectomy surgery, we must obtain information on the renal arteries and the renal vascular dominant regions. We propose a fully automatic segmentation method that combines a neural network and tensor-based graph-cut methods to precisely extract the kidney and renal arteries. First, we use a convolutional neural network to localize the kidney regions and extract tiny renal arteries with a ten…
University of Oxford（牛津大学）；Oxford University Hospitals NHS Trust（牛津大学医院NHS信托基金会）
Kidney stones represent a considerable burden for public health-care systems. Ureteroscopy with laser lithotripsy has evolved as the most commonly used technique for the treatment of kidney stones. Automated segmentation of kidney stones and laser fiber is an important initial step to performing any automated quantitative analysis of the stones, particularly stone-size estimation, that helps the surgeon decide if the stone requires more fragmentation. Factors such as turbid fluid inside the cavity, specularities, motion blur due to kidney movements and camera motion, bleeding, and stone debris…
In this paper, we formulated the kidney segmentation task in a coarse-to-fine fashion, predicting a coarse label based on the entire CT image and a fine label based on the coarse segmentation and separated image patches. A key difference between the two stages lies in how input images were preprocessed; for the coarse segmentation, each 2D CT slice was normalized to be of the same image size (but possible different pixel size), and for the fine segmentation, each 2D CT slice was first resampled to be of the same pixel size and then cropped to be of the same image size. In other words, the imag…
Deep Learning-Based Semantic Segmentation for Real-Time Kidney Imaging and Measurements with Augmented Reality-Assisted Ultrasound
Institute for Artificial Intelligence in Medicine (IKIM), Essen University Hospital (AöR), University of Duisburg-Essen（人工智能医学研究所（IKIM）、埃森大学医院（AöR）、杜伊斯堡-埃森大学）；Center for Virtual and Extended Reality in Medicine (ZvRM), University Hospital Essen (AöR)（医学虚拟与扩展现实中心（ZvRM）、埃森大学医院（AöR））；Institute of Computer Graphics and Vision (ICG), Graz University of Technology（计算机图形与视觉研究所（ICG）、格拉茨技术大学）；Department of Electrical and Information Engineering (DEI), Polytechnic University of Bari（电气与信息工程系（DEI）、巴里理工学院）；Pediatric Clinic II, University Children’s Hospital Essen, University Duisburg-Essen（儿童医院第二儿科诊所、埃森儿童医院、杜伊斯堡-埃森大学）；Medical Faculty, University of Duisburg-Essen（医学系、杜伊斯堡-埃森大学）；Cancer Research Center Cologne Essen (CCCE), West German Cancer Center, University Hospital Essen (AöR)（科隆-埃森癌症研究中心（CCCE）、西德癌症中心、埃森大学医院（AöR））；German Cancer Consortium (DKTK), Partner site University Hospital Essen (AöR)（德国癌症联盟（DKTK）、合作伙伴站点埃森大学医院（AöR））；Technical University Dortmund, Faculty of Physics（多特蒙德技术大学、物理系）；Faculty of Computer Science, University of Duisburg-Essen（计算机科学系、杜伊斯堡-埃森大学）
